Protein Alignment Syx8 and TLG1

DIOPT Version :10

• Sequence 1: NP_524113.1
• Gene: Syx8 / 39847
• FlyBaseID: FBgn0036643
• Length: 232
• Species: Drosophila melanogaster
• Sequence 2: NP_010756.3
• Gene: TLG1 / 852079
• SGDID: S000002876
• Length: 224
• Species: Saccharomyces cerevisiae
• Alignment Length: 234
• Identity: 52/234 - (22%)
• Similarity: 100/234 - (42%)
• Gaps: 47/234 - (20%)

  Fly    25 VYLNQRQQLNPRTSQFVQLTSSI-----QTGIEQLAKDMKHLKVVLDNA-ITWETSPEEELQQRR 83
            |..:.::||| |.:.::...::.     :..|:.:.||::...|.||.: |..:....|::..|.
Yeast    11 VVKDTKEQLN-RINNYITRHNTAGDDDQEEEIQDILKDVEETIVDLDRSIIVMKRDENEDVSGRE 74

  Fly    84 IDWDRLTSQLREIREKF----ANSSRSNVPAASGSAWQDQDLGPGHSNSSRNTAL----DVEALK 140
            .....:..||..::.:|    ..|:::.:|           |.....||:.||::    |.....
Yeast    75 AQVKNIKQQLDALKLRFDRRIQESTQTTIP-----------LEETVENSTLNTSMAENNDGGMSN 128

  Fly   141 QKKTEMLAQQNEGLEVLSATLSRQRQLATQLGNEVEDQNNILDNLANAMDRVETGVQRETQSIGQ 205
            ..:.:||.:|:..|:.:..|:......|..:|:|:|:|..:|||:...||.|...:.|
Yeast   129 PFQEQMLREQDVHLDGIHKTMQNLHIQAQTMGDELENQGQLLDNMDEGMDGVVNKLAR------- 186

  Fly   206 VNRRDSTWGY------------WLVIIALFVAIIVVVFV 232
             .||...|.|            .|:|:.|.| ::|:.|:
Yeast   187 -GRRQLEWVYEKNKEKYDDCCIGLLIVVLIV-LLVLAFI 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syx8	NP_524113.1	SNARE_Syntaxin8	147..205	CDD:277205	16/57 (28%)
TLG1	NP_010756.3	SNARE_NTD_Tlg1p-like	6..92	CDD:410570	16/81 (20%)
		SNARE_Syntaxin6	135..200	CDD:277204	20/72 (28%)