Protein Alignment Syx8 and Stx6

DIOPT Version :10

• Sequence 1: NP_524113.1
• Gene: Syx8 / 39847
• FlyBaseID: FBgn0036643
• Length: 232
• Species: Drosophila melanogaster
• Sequence 2: NP_067408.1
• Gene: Stx6 / 58244
• MGIID: 1926235
• Length: 255
• Species: Mus musculus
• Alignment Length: 243
• Identity: 48/243 - (19%)
• Similarity: 103/243 - (42%)
• Gaps: 46/243 - (18%)

  Fly    27 LNQRQQLNPRTSQFVQ------------LTSSIQTGIEQLAKDMKHLKVVLDNAITWETSPEEEL 79
            :|..|.|..|.::.:|            .|:.::..:..:..|::.|.         ||....|.
Mouse    18 VNTAQGLFQRWTELLQGPSAATREEIDWTTNELRNNLRSIEWDLEDLD---------ETISIVEA 73

  Fly    80 QQRRIDWDR---------LTSQLREIREKFANSSRSNVPAASGSAWQDQDLGPGHSNS------S 129
            ..|:.:.|.         :||..:.:|:.....|.|:|.|.:....:...||...|.|      .
Mouse    74 NPRKFNLDATELSIRKAFITSTRQIVRDMKDQMSASSVQALAERKNRQALLGDSSSQSWNAGVAD 138

  Fly   130 RNTALD----------VEALKQKKTEMLAQQNEGLEVLSATLSRQRQLATQLGNEVEDQNNILDN 184
            |...||          :|..:.::..::.||:|.||::|.::...:.::.::|.|:|:|..:||:
Mouse   139 RYGRLDRELQLANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLDD 203

  Fly   185 LANAMDRVETGVQRETQSIGQVNRRDSTWGYWLVIIALFVAIIVVVFV 232
            .::.::..::.:....:.:.:|:...|....|..|..||..::||:.:
Mouse   204 FSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAIAILFAVLVVVLIL 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syx8	NP_524113.1	SNARE_Syntaxin8	147..205	CDD:277205	12/57 (21%)
Stx6	NP_067408.1	Required for interaction with VPS51. /evidence=ECO:0000250|UniProtKB:Q63635	2..168		28/158 (18%)
		SNARE_NTD_STX6	5..107	CDD:410573	16/97 (16%)
		SNARE_Syntaxin6	166..231	CDD:277204	13/64 (20%)