DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syx8 and Stx8

DIOPT Version :9

Sequence 1:	NP_524113.1	Gene:	Syx8 / 39847	FlyBaseID:	FBgn0036643	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_061238.1	Gene:	Stx8 / 55943	MGIID:	1890156	Length:	236	Species:	Mus musculus

Alignment Length:	229	Identity:	59/229 - (25%)
Similarity:	121/229 - (52%)	Gaps:	8/229 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 DSWDIEYEGCERLRHQLLVYLNQRQQLNPRTSQFVQLTSSIQTGIEQLAKDMKHLKVVLDNAITW 71
            |.|...|:...::..::...:.:|.|...|..:..:||.:|:|.::.|...:..||.:|..|::.
Mouse     4 DPWFSTYDSTCQIAQEIAEKIQERNQCERRGEKTPKLTLTIRTLLKNLKVKIDLLKDLLLRAVST 68

  Fly    72 ETSPEEELQQRRIDWDRLTSQLREIREKFANSSRSNVPAASGSAWQDQDLGPGHSN------SSR 130
            ....:.|..:|:...|.|.::.|.:...|.|....  |....|:...::...|..|      ...
Mouse    69 RQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAE--PDLIRSSLMSEEAKRGTPNPWLCEEPEE 131

  Fly   131 NTALDVEALKQKKTEMLAQQNEGLEVLSATLSRQRQLATQLGNEVEDQNNILDNLANAMDRVETG 195
            ...|..:.::|::.:::.:|:.||:.||:.:|||:|:..::|||:::||.|:|:|||.::..:..
Mouse   132 TRGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEK 196

  Fly   196 VQRETQSIGQVNRRDSTWGYWLVIIALFVAIIVV 229
            ::.|.:.:..|:|:.::.|..:||:.|.|||:||
Mouse   197 LRTEARRVTLVDRKSTSCGMIMVILLLLVAIVVV 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syx8	NP_524113.1	SNARE_Syntaxin8	147..205	CDD:277205	20/57 (35%)
Stx8	NP_061238.1	SNARE_Syntaxin8	152..206	CDD:277205	19/53 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3202
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37973
Inparanoid	1	1.050	95	1.000	Inparanoid score	I5051
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54955
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003175
OrthoInspector	1	1.000	-	-		oto94066
orthoMCL	1	0.900	-	-		OOG6_103098
Panther	1	1.100	-	-	LDO	PTHR19957
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5676
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.860