DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syx8 and stx8

DIOPT Version :9

Sequence 1:	NP_524113.1	Gene:	Syx8 / 39847	FlyBaseID:	FBgn0036643	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_956669.1	Gene:	stx8 / 393346	ZFINID:	ZDB-GENE-040426-1360	Length:	235	Species:	Danio rerio

Alignment Length:	233	Identity:	61/233 - (26%)
Similarity:	122/233 - (52%)	Gaps:	15/233 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 DSWDIEYEGCERLRHQLLVYLNQRQQLNPRTSQFVQLTSSIQTGIEQLAKDMKHLKVVLDNAITW 71
            |.|...|:...||..::...:::|.:.........::..:::..:::|.:::..|:..|:.|...
Zfish     4 DLWLENYDAACRLAQEIAENIHERNRQQRTGGNPAKINMTLRASLQKLKQNIAQLRETLNRAAVQ 68

  Fly    72 ETSPEEELQQRRIDWDRLTSQLREIREKF------ANSSRSNVPA---ASGSAWQDQDLGPGHSN 127
            ....:.|..:|:...|.|.|:...:...|      |..|||.:.|   .||||     :.|...|
Zfish    69 RHIMQAEADRRQSLVDDLASRETRLNASFKGDITEAEPSRSTLMAGGNGSGSA-----VNPWLIN 128

  Fly   128 SSRNT-ALDVEALKQKKTEMLAQQNEGLEVLSATLSRQRQLATQLGNEVEDQNNILDNLANAMDR 191
            .|..| .|....:|.::.:::..|:.||:.|::.||||:|:..::|||:::||.|:|:||..:|:
Zfish   129 ESEETKGLSFGEIKNQQQQIIEAQDAGLDALASVLSRQKQMGQEIGNELDEQNEIIDDLAQLVDK 193

  Fly   192 VETGVQRETQSIGQVNRRDSTWGYWLVIIALFVAIIVV 229
            .:..::.||:.:..::.:.::.|..:||:.|.:|||||
Zfish   194 TDGRIKNETKRVKLLDSKSASCGMMVVIVLLLIAIIVV 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syx8	NP_524113.1	SNARE_Syntaxin8	147..205	CDD:277205	21/57 (37%)
stx8	NP_956669.1	SNARE_Syntaxin8	149..207	CDD:277205	21/57 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	62	1.000	Domainoid score	I10388
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37973
Inparanoid	1	1.050	95	1.000	Inparanoid score	I5054
OMA	1	1.010	-	-		QHG54955
OrthoDB	1	1.010	-	-		D1455798at2759
OrthoFinder	1	1.000	-	-		FOG0003175
OrthoInspector	1	1.000	-	-		oto39010
orthoMCL	1	0.900	-	-		OOG6_103098
Panther	1	1.100	-	-	LDO	PTHR19957
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5676
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	12.010