DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment UQCR-C2 and MAS1

DIOPT Version :9

Sequence 1:	NP_001261955.1	Gene:	UQCR-C2 / 39846	FlyBaseID:	FBgn0250814	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_013264.1	Gene:	MAS1 / 850860	SGDID:	S000004153	Length:	462	Species:	Saccharomyces cerevisiae

Alignment Length:	458	Identity:	104/458 - (22%)
Similarity:	200/458 - (43%)	Gaps:	68/458 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 LSAVNVKV-------LENKLVVA------TADATLPVSRVSLVLGAGSRNESYDIQGASHLLRLA 80
            ||.::.::       |.|.|.:|      |:.||     |.:.:.||||.|:....|.:|.|...
Yeast    16 LSTISSQIPGTRTSKLPNGLTIATEYIPNTSSAT-----VGIFVDAGSRAENVKNNGTAHFLEHL 75

  Fly    81 GGLSTQNSTAFAIARNIQQVGGTLTTWGDRELVGYTVTTTADNAETGLRYLQDLLQPAFKPWELV 145
            ....|||.:...|...|:.:|..|..:..||...|...:..::....:..|.|:|..:     ::
Yeast    76 AFKGTQNRSQQGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKS-----VL 135

  Fly   146 DNA------KTVVNQLNAVST--EERAIELVHKAAFRN-GLGNSIYSPRFQLGKLSSESLLHYVA 201
            ||:      ..::.:...|..  :|...:.:|:..::: .||.:|..|...:..::...|..|:.
Yeast   136 DNSAIERERDVIIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYIT 200

  Fly   202 QTFAAGRAAVVGVG-IDNNTLAGFAQTL---------QFPSGGSKAASANWYGGD--ARKDT--S 252
            :.:...|..:.|.| :|:..|..:||..         ..|.|..:.....:..|:  .:::|  :
Yeast   201 KNYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIKENTLPT 265

  Fly   253 GHRAVVAVAGQGAAASNHKEALAFAIL----EQALGAKAATKRGT-SAGLFGEAVNCAGGVGASV 312
            .|.| :|:.|...:|.::..|||...:    ::|:|.      || |......|.:..|.:..|.
Yeast   266 THIA-IALEGVSWSAPDYFVALATQAIVGNWDRAIGT------GTNSPSPLAVAASQNGSLANSY 323

  Fly   313 KAVNASYSDAGLFGFVVSADSKDIGKTVEFLV-------RGLKSASVSDKDVARGKALLKARIIS 370
            .:.:.||:|:||:|..:..||.:  ..|:.:|       :.:||..:||.:|.|.||.|||.::.
Yeast   324 MSFSTSYADSGLWGMYIVTDSNE--HNVQLIVNEILKEWKRIKSGKISDAEVNRAKAQLKAALLL 386

  Fly   371 RYSSDGGLIKEIGRQAALTRNVLEADALLGAIDGISQSQ-VQEAAKKVGSSKLAVGAIGHLANVP 434
            .......::::||||...|...|..:.:...:|.|::.. :..|..::.:..:::.|:|:.:.||
Yeast   387 SLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQNKPVSMVALGNTSTVP 451

  Fly   435 YAS 437
            ..|
Yeast   452 NVS 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
UQCR-C2	NP_001261955.1	PqqL	22..417	CDD:223685	99/436 (23%)
		Peptidase_M16	41..185	CDD:279066	35/158 (22%)
		Peptidase_M16_C	190..364	CDD:282978	47/199 (24%)
MAS1	NP_013264.1	PqqL	12..453	CDD:223685	103/455 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0612
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810