Protein Alignment UQCR-C2 and UQCRC1

DIOPT Version :9

• Sequence 1: NP_001261955.1
• Gene: UQCR-C2 / 39846
• FlyBaseID: FBgn0250814
• Length: 440
• Species: Drosophila melanogaster
• Sequence 2: NP_003356.2
• Gene: UQCRC1 / 7384
• HGNCID: 12585
• Length: 480
• Species: Homo sapiens
• Alignment Length: 460
• Identity: 107/460 - (23%)
• Similarity: 191/460 - (41%)
• Gaps: 52/460 - (11%)

  Fly     9 SLLRAIAKRGYATCPRPVGDLSAVNVKVLENKLVVATADATLPVSRVSLVLGAGSRNESYDIQGA 73
            :|||..|.|..||..:.:..:....|.:|:|.|.||:..::.|...|.:.:..|||.|:....||
Human    25 ALLRTPALRSTATFAQALQFVPETQVSLLDNGLRVASEQSSQPTCTVGVWIDVGSRFETEKNNGA 89

  Fly    74 SHLLRLAGGLSTQNSTAFAIARNIQQVGGTLTTWGDRELVGYTVTTTADNAETGLRYLQDLLQPA 138
            .:.|.......|:|....|:.:.::.:|..|..:..||...|.:...:.:....:..|.|::|..
Human    90 GYFLEHLAFKGTKNRPGSALEKEVESMGAHLNAYSTREHTAYYIKALSKDLPKAVELLGDIVQNC 154

  Fly   139 FKPWELVDNAKTVV---NQLNAVSTEERAIELVHKAAFR-NGLGNSIYSPRFQLGKLSSESLLHY 199
            ......::..:.|:   .|.|..|..:.....:|..||: ..|..::..|...:.|||...|..|
Human   155 SLEDSQIEKERDVILREMQENDASMRDVVFNYLHATAFQGTPLAQAVEGPSENVRKLSRADLTEY 219

  Fly   200 VAQTFAAGRAAVVGV-GIDNNTLAGFAQTLQFPSGG---SKAASA-------NWYGGDARKDTSG 253
            ::..:.|.|..:... |:::..|...||.   ..||   :.|..|       .:.|.:.|
Human   220 LSTHYKAPRMVLAAAGGVEHQQLLDLAQK---HLGGIPWTYAEDAVPTLTPCRFTGSEIR----- 276

  Fly   254 HR--------AVVAVAGQGAAASNHKEALAFAILEQALGAKAATKRG---TSAGLFGEAVNCAGG 307
            ||        ..:||.|.|.|:.::   :|..:....:|....|..|   .|:.|...||  |..
Human   277 HRDDALPFAHVAIAVEGPGWASPDN---VALQVANAIIGHYDCTYGGGVHLSSPLASGAV--ANK 336

  Fly   308 VGASVKAVNASYSDAGLFGFVVSADSKDIGKTVEFLVRG---LKSASVSDKDVARGKALLKARII 369
            :..|.:..:..|::.||.|.....|...|...: |:::|   ....|.::.:|||||.:|:..::
Human   337 LCQSFQTFSICYAETGLLGAHFVCDRMKIDDMM-FVLQGQWMRLCTSATESEVARGKNILRNALV 400

  Fly   370 SRYSSDGGLIKEIGRQAALTRN----VLEADALLGAIDGISQSQVQE-AAKKVGSSKLAVGAIGH 429
            |.......:.::||| :.||..    :.|.::.:..:|.   |.|:| .:|.:.....||...|.
Human   401 SHLDGTTPVCEDIGR-SLLTYGRRIPLAEWESRIAEVDA---SVVREICSKYIYDQCPAVAGYGP 461

  Fly   430 LANVP 434
            :..:|
Human   462 IEQLP 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UQCR-C2	NP_001261955.1	PqqL	22..417	CDD:223685	96/428 (22%)
		Peptidase_M16	41..185	CDD:279066	31/147 (21%)
		Peptidase_M16_C	190..364	CDD:282978	48/198 (24%)
UQCRC1	NP_003356.2	PqqL	41..469	CDD:223685	100/444 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0612
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810