DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment UQCR-C2 and Uqcrc2

DIOPT Version :9

Sequence 1:	NP_001261955.1	Gene:	UQCR-C2 / 39846	FlyBaseID:	FBgn0250814	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_001006971.1	Gene:	Uqcrc2 / 293448	RGDID:	1359150	Length:	452	Species:	Rattus norvegicus

Alignment Length:	418	Identity:	144/418 - (34%)
Similarity:	222/418 - (53%)	Gaps:	22/418 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 LENKLVVATADATLPVSRVSLVLGAGSRNESYDIQGASHLLRLAGGLSTQNSTAFAIARNIQQVG 101
            |.|.||:|:.:...|:||:.|.:.||||.|:|:..|.|||||||..|:|:.:::|.|.|.|:.||
  Rat    42 LPNGLVIASLENYAPLSRIGLFIKAGSRYENYNYLGTSHLLRLASTLTTKGASSFKITRGIEAVG 106

  Fly   102 GTLTTWGDRELVGYTVTTTADNAETGLRYLQDL-LQPAFKPWEL--------VDNAKTVVNQLNA 157
            |.|:....||.:.|||....|:.|..:.:|.:: ..|.|:.||:        :|.|....|
  Rat   107 GKLSVTATRENMAYTVEGIRDDIEILMEFLLNVTTAPEFRRWEVAALRSQLKIDKAVAFQN---- 167

  Fly   158 VSTEERAIELVHKAAFRNGLGNSIYSPRFQLGKLSSESLLHYVAQTFAAGRAAVVGVGIDNNTLA 222
              .:.|.||.:|..|::|.|.|.:|.|.:::||::||.|.::|...|.:.|.|:||:|:.::.|.
  Rat   168 --PQTRIIENLHDVAYKNALANPLYCPDYRMGKITSEELHYFVQNHFTSARMALVGLGVSHSILK 230

  Fly   223 GFA-QTLQFPSG-GSKAASANWYGGDARKDTSGHRAVVAVAGQGAAASNHKEALAFAILEQALGA 285
            ..| |.|....| |...|.|.:.||:.|:....:....|:..:.||..| .||.||::|:..|||
  Rat   231 EVAEQFLNIRGGLGLAGAKAKYRGGEIREQNGDNLVHAAIVAESAAIGN-AEANAFSVLQHLLGA 294

  Fly   286 KAATKRG-TSAGLFGEAVNCAGGVGASVKAVNASYSDAGLFG-FVVS--ADSKDIGKTVEFLVRG 346
            ....||| .:..|..::|.........|.|.||||||:|||| :.||  |.:.|:.......|:.
  Rat   295 GPHIKRGNNTTSLLSQSVAKGSQQPFDVSAFNASYSDSGLFGIYTVSQAAAAGDVINAAYNQVKA 359

  Fly   347 LKSASVSDKDVARGKALLKARIISRYSSDGGLIKEIGRQAALTRNVLEADALLGAIDGISQSQVQ 411
            :...::|..||...|..|||..:....:..|.:.|||.||..|.:.:....:|..||.::.:.|.
  Rat   360 VAQGNLSSADVQAAKNKLKAGYLMSVETSEGFLSEIGSQALATGSYMPPPTVLQQIDAVADADVV 424

  Fly   412 EAAKKVGSSKLAVGAIGHLANVPYASDL 439
            :||||..|.|.::.|.|:|.:.|:..:|
  Rat   425 KAAKKFVSGKKSMTASGNLGHTPFLDEL 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
UQCR-C2	NP_001261955.1	PqqL	22..417	CDD:223685	136/394 (35%)
		Peptidase_M16	41..185	CDD:279066	55/152 (36%)
		Peptidase_M16_C	190..364	CDD:282978	60/179 (34%)
Uqcrc2	NP_001006971.1	PqqL	30..435	CDD:223685	138/399 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	92	1.000	Domainoid score	I7493
eggNOG	1	0.900	-	-		E1_COG0612
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37764
Inparanoid	1	1.050	216	1.000	Inparanoid score	I3525
OMA	1	1.010	-	-		QHG51844
OrthoDB	1	1.010	-	-		D1000258at2759
OrthoFinder	1	1.000	-	-		FOG0003081
OrthoInspector	1	1.000	-	-		oto98919
orthoMCL	1	0.900	-	-		OOG6_103720
Panther	1	1.100	-	-	LDO	PTHR11851
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5219
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840