DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment UQCR-C2 and mas2

DIOPT Version :9

Sequence 1:	NP_001261955.1	Gene:	UQCR-C2 / 39846	FlyBaseID:	FBgn0250814	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_595859.2	Gene:	mas2 / 2540713	PomBaseID:	SPBC18E5.12c	Length:	502	Species:	Schizosaccharomyces pombe

Alignment Length:	483	Identity:	104/483 - (21%)
Similarity:	183/483 - (37%)	Gaps:	95/483 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ACNASKTSLLRAIAKRG--YATCPRPVGDLSAVNVKVLENKLVVATADATLPVSRVSLVLGAGSR 64
            |.|..:|..|    |.|  |...||| |..|.:.|.|                       .||||
pombe    50 ALNEVRTEKL----KNGVTYVCDPRP-GHFSGLGVYV-----------------------KAGSR 86

  Fly    65 NESYDIQGASHLLRLAGGLSTQNSTAFAIARNIQQVGGTLTTWGDRELVGYTVTTTADNAETGLR 129
            .|:....|.||.:......:|:.:....:...::.:||.......||.:.|......|:.::..:
pombe    87 YETKKFSGVSHFMDRLAFQATERTPVGEMKAKLENLGGNYMCSTSRESMIYQAAVFNDDVKSMSK 151

  Fly   130 YL-QDLLQPAFKPWELVDNAKTVVNQLNAVSTEERAI--ELVHKAAFRNG-LGNSIYSPRFQLGK 190
            .| :.:|.|..:..:||....:::.:.:.:.|:..|:  |..|..||:|. |||.:.....::..
pombe   152 LLAETVLAPKIQEDDLVHYRDSIIYENSELWTKPDALLGEFAHVTAFQNNTLGNCLLCTPDKVNG 216

  Fly   191 LSSESLLHYVAQTFAAGRAAVVGVGIDNNTLAGFAQTL--QFPSGG---SKAASANWYGGDARKD 250
            :::.|:..|:...:......:...||.........:.|  ..||..   .:|..:::.||.....
pombe   217 ITATSIREYLKYFYRPEHLTLAYAGIPQEIAKEITKELYGHLPSSSLPPLEAIPSHYTGGFMGIK 281

  Fly   251 TSGHRAV--------VAVAGQGAAASNHKEALAFAILEQALGAKAATKRGTSAGLFGEAVNCAGG 307
            .|....|        |.:|.:|...:: .:..|.|.|:..||         ..|.|.     |||
pombe   282 KSEAPPVPYQQEFTHVVIAMEGLPVTD-PDIYALACLQFLLG---------GGGSFS-----AGG 331

  Fly   308 VGASV------------------KAVNASYSDAGLFGFVVSADSKDIGKTVEFLVRGLKSA--SV 352
            .|..:                  .|.|.||:|:||||..|:............::|.|.:.  ||
pombe   332 PGKGMYSRLYLNVLNQYPWVETCMAFNHSYTDSGLFGMFVTILDDAAHLAAPLIIRELCNTVLSV 396

  Fly   353 SDKDVARGKALLKARIISRYSSDGGLIKEIGRQAALTRN--VLEADALLGAIDGISQSQVQEAAK 415
            :.::..|.|..||:.::....|....::::|||.. |:|  .:....::..||.::.|.:...|:
pombe   397 TSEETERAKNQLKSSLLMNLESRMISLEDLGRQIQ-TQNGLYITPKEMIEKIDALTPSDLSRVAR 460

  Fly   416 KV----------GSSKLAVGAIGHLANV 433
            :|          |:.|..|...|::..|
pombe   461 RVLTGNVSNPGNGTGKPTVLIHGNVDEV 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
UQCR-C2	NP_001261955.1	PqqL	22..417	CDD:223685	91/433 (21%)
		Peptidase_M16	41..185	CDD:279066	30/147 (20%)
		Peptidase_M16_C	190..364	CDD:282978	42/206 (20%)
mas2	NP_595859.2	PqqL	39..491	CDD:223685	104/483 (22%)
		Peptidase_M16	71..210	CDD:279066	35/162 (22%)
		Peptidase_M16_C	217..408	CDD:282978	42/205 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0612
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11851
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910