Protein Alignment UQCR-C2 and PMPCA

DIOPT Version :9

• Sequence 1: NP_001261955.1
• Gene: UQCR-C2 / 39846
• FlyBaseID: FBgn0250814
• Length: 440
• Species: Drosophila melanogaster
• Sequence 2: XP_005266116.1
• Gene: PMPCA / 23203
• HGNCID: 18667
• Length: 563
• Species: Homo sapiens
• Alignment Length: 476
• Identity: 104/476 - (21%)
• Similarity: 189/476 - (39%)
• Gaps: 83/476 - (17%)

  Fly    23 PRPV------GDLSAVNVKVLENKLVVATADATLPVSRVSLVLGAGSRNESYDIQGASHLL-RLA 80
            |:||      .:.....|..|:|.|.||:.:.......|.:::.:|||.|:..:.|.:|.| :||
Human    52 PKPVFATVDGQEKFETKVTTLDNGLRVASQNKFGQFCTVGILINSGSRYEAKYLSGIAHFLEKLA 116

  Fly    81 GGLSTQNSTAFAIARNIQQVGGTLTTWGDRELVGYTVTTTADNAETGLRYLQD-LLQPAFKPWEL 144
            ...:.:..:...|...:::.||.......|:...|.|:..:...:|.:..|.| :|||.....|:
Human   117 FSSTARFDSKDEILLTLEKHGGICDCQTSRDTTMYAVSADSKGLDTVVALLADVVLQPRLTDEEV 181

  Fly   145 VDNAKTVVNQLNAVS----TEERAIELVHKAAFR-NGLGNSIYSPRFQLGKLSSESLLHYVAQTF 204
            ......|..:|..::    .|....|::|:||:| |.:|...:.|...:.|::.|.|..|:...:
Human   182 EMTRMAVQFELEDLNLRPDPEPLLTEMIHEAAYRENTVGLHRFCPTENVAKINREVLHSYLRNYY 246

  Fly   205 AAGRAAVVGVGIDNNTLAGFAQTLQF---PSGGSKAA------SANWYGGDAR--KDTSG----- 253
            ...|..:.|||:::..|...|:....   |:.||..|      .|.:.||.|:  :|.|.
Human   247 TPDRMVLAGVGVEHEHLVDCARKYLLGVQPAWGSAEAVDIDRSVAQYTGGIAKLERDMSNVSLGP 311

  Fly   254 -------HRAVVAVAGQGAAASNHKEALAFAILEQALGAKAATKRGTSAGLFGEAVNCAGGVGA- 310
                   |    .:.|..:.:...::.:.||:|...:|         ..|.|.     |||.|.
Human   312 TPIPELTH----IMVGLESCSFLEEDFIPFAVLNMMMG---------GGGSFS-----AGGPGKG 358

  Fly   311 -----------------SVKAVNASYSDAGLFGFVVSADSKDIGKTVEFLVRG--LKSASVSDKD 356
                             :..:.:.||.|.||.....|||.:.:.:.||.:.:.  |...:|...:
Human   359 MFSRLYLNVLNRHHWMYNATSYHHSYEDTGLLCIHASADPRQVREMVEIITKEFILMGGTVDTVE 423

  Fly   357 VARGKALLKARIISRYSSDGGLIKEIGRQAALTRNVLEADALLGAI-------DGISQSQVQEAA 414
            :.|.|..|.:.::....|...:.:::|||...||:......|...|       :|:.|:..:...
Human   424 LERAKTQLTSMLMMNLESRPVIFEDVGRQVLATRSRKLPHELCTLIREYRRGSEGLPQASARLRG 488

  Fly   415 KKVGSSKLAVGA--IGHLANV 433
            .::...:..||.  :.|..|:
Human   489 GRLALPQAVVGLWYVHHTQNL 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UQCR-C2	NP_001261955.1	PqqL	22..417	CDD:223685	100/456 (22%)
		Peptidase_M16	41..185	CDD:279066	36/150 (24%)
		Peptidase_M16_C	190..364	CDD:282978	46/216 (21%)
PMPCA	XP_005266116.1	PqqL	65..465	CDD:223685	93/417 (22%)
		Peptidase_M16	77..227	CDD:279066	35/149 (23%)
		Peptidase_M16_C	232..431	CDD:282978	46/216 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0612
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810