DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rpn12 and Psmd8

DIOPT Version :9

Sequence 1:	NP_648904.1	Gene:	Rpn12 / 39845	FlyBaseID:	FBgn0028693	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_080821.3	Gene:	Psmd8 / 57296	MGIID:	1888669	Length:	353	Species:	Mus musculus

Alignment Length:	259	Identity:	130/259 - (50%)
Similarity:	186/259 - (71%)	Gaps:	3/259 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LYKELTAEWSKRPPNTVKCGQLLDQLKVALVKMAFLPTDGNDAQSSKKQLILARSVLEVAVEHSV 71
            :|::|..||:::.||..|||:.|.:||:.|:::.||||.|  .:.:|:||||||.:||:..:.|:
Mouse    97 MYEQLKDEWNRKNPNLSKCGEELGRLKLVLLELNFLPTTG--TKLTKQQLILARDILEIGAQWSI 159

  Fly    72 LSKDLLAFERYMAQLKCYYYDYAKIIGESESKYKLLGLNLLYLLSGNRVSDFHTELELLSVDVIQ 136
            |.||:.:||||||||||||:||.:.:.||...::|||||||:|||.|||::||||||.|....||
Mouse   160 LCKDIPSFERYMAQLKCYYFDYKEQLPESAYMHQLLGLNLLFLLSQNRVAEFHTELERLPAKDIQ 224

  Fly   137 HNQFIRPILALEQYIMEGRYNKIFQAKSTVPVEVYSYFMDLLLETVRDEIGACIEKSYDKISAKD 201
            .|.:|:..::||||:|||.|||:|.||..:|.|.|::|:|:||:|:||||..||||:|:||...:
Mouse   225 TNVYIKHPVSLEQYLMEGSYNKVFLAKGNIPAESYTFFIDILLDTIRDEIAGCIEKAYEKILFAE 289

  Fly   202 AAKRLNLRVPDEIKAFGAKRQWKLEASGDYSFTDRSVKPKE-LLPSEELAEQVLSYARDLEMIV 264
            |.:.|....|.::..:..||.|.|..:..|||..:..||:: .:||.|||:||:.|||.|||||
Mouse   290 ATRILFFSTPKKMTDYAKKRGWVLGPNNYYSFASQQQKPEDSTIPSTELAKQVIEYARQLEMIV 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpn12	NP_648904.1	CSN8_PSD8_EIF3K	119..230	CDD:287089	52/110 (47%)
Psmd8	NP_080821.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..25
Psmd8	NP_080821.3	CSN8_PSD8_EIF3K	204..318	CDD:287089	54/113 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835055
Domainoid	1	1.000	142	1.000	Domainoid score	I4687
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37686
Inparanoid	1	1.050	263	1.000	Inparanoid score	I3076
Isobase	1	0.950	-	0	Normalized mean entropy	S2152
OMA	1	1.010	-	-		QHG53806
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003512
OrthoInspector	1	1.000	-	-		otm42720
orthoMCL	1	0.900	-	-		OOG6_102164
Panther	1	1.100	-	-	LDO	PTHR12387
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1201
SonicParanoid	1	1.000	-	-		X2884
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.880