| Sequence 1: | NP_001261954.1 | Gene: | Smn / 39844 | FlyBaseID: | FBgn0036641 | Length: | 226 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_000335.1 | Gene: | SMN1 / 6606 | HGNCID: | 11117 | Length: | 294 | Species: | Homo sapiens |
| Alignment Length: | 280 | Identity: | 74/280 - (26%) |
|---|---|---|---|
| Similarity: | 117/280 - (41%) | Gaps: | 93/280 - (33%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 2 SDETNAAVWDDSLLVKTYDESVGLAREAL---------------ARRLADSTNKREEENAAAAEE 51
Fly 52 EAGEISATGGATSPEPVSFKVGDYARATY-VDGVDYEGAVVSINEEKGTCVLRYLGYENEQEVLL 115
Fly 116 VDLL-PSWGKRVRREQFLIAKKDEDE-QLSRPKA----SAGSHSKT--PKSSRRSRI-------- 164
Fly 165 ------------------------------------SGGLVMPPMPPVPPMIVGQGDGAEQDFVA 193
Fly 194 MLTAWYMSGYYTGLYQGKKE 213 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Smn | NP_001261954.1 | SMN | 2..215 | CDD:283622 | 74/280 (26%) |
| TUDOR | 68..122 | CDD:295375 | 23/55 (42%) | ||
| SMN1 | NP_000335.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..32 | 2/3 (67%) | |
| P1 (binding site for GEMIN2) | 13..44 | 7/17 (41%) | |||
| SMN | 27..291 | CDD:310529 | 74/280 (26%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 59..88 | 5/28 (18%) | |||
| Required for interaction with RPP20/POP7 | 97..209 | 32/113 (28%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 156..222 | 11/65 (17%) | |||
| P2 (binding site for SNRPB) | 240..267 | 8/30 (27%) | |||
| Required for interaction with SYNCRIP. /evidence=ECO:0000269|PubMed:11574476 | 279..294 | 1/4 (25%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165153166 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG4327 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 69 | 1.000 | Inparanoid score | I5336 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG47795 | |
| OrthoDB | 1 | 1.010 | - | - | D1316275at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0006496 | |
| OrthoInspector | 1 | 1.000 | - | - | oto90516 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_108123 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR13681 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R3285 |
| SonicParanoid | 1 | 1.000 | - | - | X4739 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 14 | 13.800 | |||||