Protein Alignment Smn and smn1

DIOPT Version :10

• Sequence 1: NP_524112.1
• Gene: Smn / 39844
• FlyBaseID: FBgn0036641
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: NP_593088.1
• Gene: smn1 / 2542002
• PomBaseID: SPAC2G11.08C
• Length: 152
• Species: Schizosaccharomyces pombe
• Alignment Length: 216
• Identity: 46/216 - (21%)
• Similarity: 74/216 - (34%)
• Gaps: 82/216 - (37%)

  Fly     3 DETNAAVWDDSLLVKTYDESVGLAREALARRLADSTNKREEENAAAAEEEAGEISATGGATSPEP 67
            |::...|||||.|...:                        |.|....::...|.|.||.:.|:
pombe     2 DQSQKEVWDDSELRNAF------------------------ETALHEFKKYHSIEAKGGVSDPD- 41

  Fly    68 VSFKVGDYARATYVDGVDYEGAVVSINEEKGTCVLRYLGYENEQEV-------LLVDLLPSWGKR 125
                       :.:||   |..:.:...|:....|.    |.||.:       |..|
pombe    42 -----------SRLDG---EKLISAARTEESISKLE----EGEQMINQQTETTLEGD-------- 80

  Fly   126 VRREQFLIAKKDEDEQLSRPKA-SAGSHSKTPKSSRRSRISGGLVMPPMPPVPPMIVGQGDGAEQ 189
            ...:||...|...||   :|:. :|.:|.:                  ...|||.|  :|...::
pombe    81 THIQQFADNKGLSDE---KPETRAAETHQE------------------FMEVPPPI--RGLTYDE 122

  Fly   190 DFVAMLTAWYMSGYYTGLYQG 210
            .:..::.:||.:||||||.:|
pombe   123 TYKKLIMSWYYAGYYTGLAEG 143

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smn	NP_524112.1	SMN	2..215	CDD:428716	46/216 (21%)
		Tudor_SMN	70..124	CDD:410469	10/60 (17%)
smn1	NP_593088.1	SMN_N	4..35	CDD:439367	10/54 (19%)
		SMN_C	120..147	CDD:439368	9/24 (38%)