Protein Alignment nxf2 and nxf1a

DIOPT Version :9

• Sequence 1: NP_524111.3
• Gene: nxf2 / 39843
• FlyBaseID: FBgn0036640
• Length: 841
• Species: Drosophila melanogaster
• Sequence 2: XP_009306018.1
• Gene: nxf1a / 751719
• ZFINID: ZDB-GENE-060825-299
• Length: 642
• Species: Danio rerio
• Alignment Length: 521
• Identity: 117/521 - (22%)
• Similarity: 222/521 - (42%)
• Gaps: 101/521 - (19%)

  Fly   380 IAHLVNNCNLEMT----IPTGDRIFRYYLR-----MNVSTVKQHHVDPE-ECIQKAVSQCYV--- 431
            :..|.|.|.:..|    ...||:: .:||.     ..:|.:.:..:|.: :.:...::.||.
Zfish   161 LTSLQNLCPIAFTPLHYTTEGDKV-HFYLEDTTTASALSKLSRRILDSDGQRVVVLMNSCYFPPF 224

  Fly   432 --AQNRMLNLE--------RFHSRECLKDVMVSLSSPKILTY-VLSVASRKFMTTCSE------- 478
              ::.|:.:||        ||...:...|:....:.|::::: |..:.:||   .|.:
Zfish   225 LKSELRLEDLELLKLCLSKRFDDSQKSLDLTSIRTDPELVSHNVDIILNRK---NCMQAVIKIIQ 286

  Fly   479 --------IRLCHNKVLVLDG-AHVLGMMGCLRAVDLSHNWVQDLSSIHSLGNLPLKSLVLHGNK 534
                    :.|..||:..||| ..::.....|::::||.|.::....:..:....|..|.|.||.
Zfish   287 ESIPELLSLNLSKNKLYKLDGLTELVNKAPNLQSLNLSCNELKSHCELDKVKGFRLVELCLDGNP 351

  Fly   535 LCRNYRLPSEYVRAVKEVFPQLTTLDG--------VDLQTNPGQSLQK-NFLCDTGAYELVGAFL 590
            ||..::..:.|:.||::.||:|..|||        .:::|:....|.| :.........|:..||
Zfish   352 LCDRFKDQTTYISAVQKCFPRLLRLDGHVLSLPICFEVETSSNIPLCKGSHFVSNEIQGLIQRFL 416

  Fly   591 ENYLREFENDEFRHNLYKYYSENSIFTLTCNYNVVQNHQTPKILQRLSKYNRHARNLRN-KD--- 651
            |.|...:::.: |..|.:.|.|::.|:| | ...:.|....|:     .|.:::||::| ||
Zfish   417 EQYYSIYDSGD-RQPLLEAYHESACFSL-C-LPSISNPSRYKL-----DYFKNSRNVKNIKDSPT 473

  Fly   652 ------YSKASDGVFFGCTYIVEILLQLPRVTHDFHSLQTDVMHYNGKGAVIYVAGLLRDEPPST 710
                  :::.:         :|..|.:||:..||.:|:..||..|........|:|:.::....:
Zfish   474 RFRLLKHTRLT---------VVACLNELPKTQHDINSINVDVNAYASTLLAFTVSGVFKEVDDQS 529

  Fly   711 RNGHGSKTDIGGVLLGFSRQFVVTFDEANLGLGKRARRLKIANERLHITNPSKTAIRNAFSVNFP 775
            .:          :...|||.| ||....|.|       |.|.|:.|.:.|.:...|:.||:.  |
Zfish   530 ED----------LFKAFSRVF-VTVPAQNSG-------LCIVNDELFVRNTTMEEIQCAFTT--P 574

  Fly   776 DPSERQAEEDSLDVKDHKLL-LFQEVTGLISTWVTSIVEEADWDFERALKLFIQKNADHEIPDLA 839
            ..|...:....|.....::| .|.:::.:...|....:|:..|||::|.::|.:..|...||:.|
Zfish   575 TQSPSSSPVPILSAYQQEMLSAFSQMSEMNLQWSQKCLEDNAWDFQQAAQIFAELQAHGMIPEAA 639

  Fly   840 F 840
            |
Zfish   640 F 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nxf2	NP_524111.3	leucine-rich repeat	434..474	CDD:275382	10/48 (21%)
		leucine-rich repeat	475..500	CDD:275382	7/40 (18%)
		leucine-rich repeat	501..524	CDD:275382	4/22 (18%)
		leucine-rich repeat	525..555	CDD:275382	11/29 (38%)
		TAP_C	779..841	CDD:197882	15/63 (24%)
nxf1a	XP_009306018.1	Tap-RNA_bind	142..223	CDD:286271	12/62 (19%)
		leucine-rich repeat	249..291	CDD:275382	6/44 (14%)
		LRR_4	290..336	CDD:289563	10/45 (22%)
		leucine-rich repeat	292..317	CDD:275382	6/24 (25%)
		leucine-rich repeat	318..341	CDD:275382	4/22 (18%)
		leucine-rich repeat	342..372	CDD:275382	11/29 (38%)
		NTF2	413..561	CDD:238403	43/182 (24%)
		TAP_C	579..641	CDD:197882	15/62 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581701
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3763
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D442228at33208
OrthoFinder	1	1.000	-	-		FOG0000862
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10662
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R710
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.840