Protein Alignment nxf2 and Nxf7

DIOPT Version :9

• Sequence 1: NP_524111.3
• Gene: nxf2 / 39843
• FlyBaseID: FBgn0036640
• Length: 841
• Species: Drosophila melanogaster
• Sequence 2: NP_001032293.1
• Gene: Nxf7 / 501621
• RGDID: 1566170
• Length: 614
• Species: Rattus norvegicus
• Alignment Length: 576
• Identity: 130/576 - (22%)
• Similarity: 228/576 - (39%)
• Gaps: 124/576 - (21%)

  Fly   286 NMLHKIFSPLDVEIDLEVDGARIDTNNMWKLPEFENSQHWHAFMIPDPSHEFNQEVFFDFFFIRL 350
            |.:|.:.|.....:|...|..||         :|.......|:.:.|.|::.:.| .|:...|.:
  Rat   130 NSVHSLCSVPFTPVDFHCDKYRI---------QFFVQDSSIAYALKDVSYKISSE-DFEKIPIFV 184

  Fly   351 DPTLSNFYPCYYKYINTEHVFLVRNCF--DQIAHLVNNCNLEMTIPTGDRIFRYYLRMNVSTVKQ 413
            :|:::              .:.|:|.|  :|:..|    .|.|.       .||.:..:...:|:
  Rat   185 NPSVA--------------PYSVQNRFTREQMEQL----KLAMK-------KRYDISQHALCLKK 224

  Fly   414 HHVDPEECIQKAVSQCYVAQNRMLNLERFHSRECLKDVM--VSLSSPKILTYVLSVASRKFMTTC 476
            ...||:          .:..|..:.|.|   |.|:...:  :....||:|:
  Rat   225 LRFDPD----------LMNHNIDMILNR---RSCMTATLQIIQEDFPKLLS-------------- 262

  Fly   477 SEIRLCHNKVLVLDGA-HVLGMMGCLRAVDLSHNWVQDLSSIHSLGNLPLKSLVLHGNKLCRNYR 540
              :.|..||:..||.. .|:.....|:.::||.|.::....:..:..|.|:.|.|.||.||..:.
  Rat   263 --LNLSSNKLFQLDSLFDVVKKAPKLKILNLSKNMLRTAWELEKIRGLKLEQLWLEGNPLCSTFP 325

  Fly   541 LPSEYVRAVKEVFPQLTTLDGVDLQTNPGQSLQKN---------FLCDTGAYELVGAFLENYLRE 596
            ..|.||.|:.|.||||:.|||..|..:.|..:::.         |.........|..||::|...
  Rat   326 DHSSYVSAILEYFPQLSCLDGRKLPLSTGMDIEEPQLMKPRKAIFKGSEAIKNQVQQFLQDYYLI 390

  Fly   597 FENDEFRHNLYKYYSENSIFTLTCNYNVVQNHQTPKILQRLSKYNRHARNLRN-KDYSKASDGVF 660
            ::::| |..|...|.|.:.|:||..:|     .:...|..:..|.:..|:::| |::......:.
  Rat   391 YDSEE-RQGLLSIYHEQACFSLTIPFN-----PSGPDLSSMCGYFKDERDVKNPKEFHIQRQLLK 449

  Fly   661 FGCTYIVEILLQLPRVTHDFHSLQTDVMHYNGKGAVIYVAGLLRDEPPSTRNGHGSKTDIGGVLL 725
            :....||..|..||:..|.|:|.|.|:.....|.....|:||.::...|::.          .:.
  Rat   450 YTKEDIVGYLRTLPKTLHVFNSFQVDICFQMEKTLCFSVSGLFKEVEGSSQE----------CIR 504

  Fly   726 GFSRQFVVTFDEANLGLGKRARRLKIANERLHITNPSKTAIRNAFSVNFPDPSERQAEEDSLDVK 790
            .|.|.|:..|:.::        .|.|.|::|.:.|||...|:.||:::.|           ....
  Rat   505 AFMRIFIAVFESSS--------NLCIVNDQLFVRNPSPDEIQGAFAISSP-----------TSCS 550

  Fly   791 DHKLLLFQE----------VTGLISTWVTSIVEEADWDFERALKLFIQKNADHEIP 836
            ..||:|.||          .:|:...|....:::..||:.||.::|.......:||
  Rat   551 SFKLVLSQEQQRMVQAFSTQSGMKLEWSQKCLDDNKWDYTRAAEVFTMLQTKSKIP 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nxf2	NP_524111.3	leucine-rich repeat	434..474	CDD:275382	8/41 (20%)
		leucine-rich repeat	475..500	CDD:275382	6/25 (24%)
		leucine-rich repeat	501..524	CDD:275382	4/22 (18%)
		leucine-rich repeat	525..555	CDD:275382	13/29 (45%)
		TAP_C	779..841	CDD:197882	14/68 (21%)
Nxf7	NP_001032293.1	Tap-RNA_bind	110..191	CDD:401194	15/84 (18%)
		leucine-rich repeat	217..259	CDD:275382	8/54 (15%)
		LRR_8	258..320	CDD:404697	19/77 (25%)
		leucine-rich repeat	260..285	CDD:275382	7/40 (18%)
		leucine-rich repeat	286..309	CDD:275382	4/22 (18%)
		leucine-rich repeat	310..340	CDD:275382	13/29 (45%)
		NTF2_like	380..531	CDD:415585	41/174 (24%)
		TAP_C	549..611	CDD:197882	14/58 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341686
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3763
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D442228at33208
OrthoFinder	1	1.000	-	-		FOG0000862
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10662
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	7.810