DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nxf2 and nxf4

DIOPT Version :9

Sequence 1:	NP_524111.3	Gene:	nxf2 / 39843	FlyBaseID:	FBgn0036640	Length:	841	Species:	Drosophila melanogaster
Sequence 2:	NP_731156.1	Gene:	nxf4 / 40884	FlyBaseID:	FBgn0051501	Length:	301	Species:	Drosophila melanogaster

Alignment Length:	206	Identity:	47/206 - (22%)
Similarity:	89/206 - (43%)	Gaps:	43/206 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   390 EMTIPTGDRIFRYY----LRMNVSTVKQHHVDPEECIQKAVSQCYVAQNRMLNLERFHSRECLKD 450
            ::.:...||:.:.:    ||::::.|.....||.|              |.|:|..|:..:.|..
  Fly   116 QIWLKVSDRMPKIWINSILRLHLTMVLLDRYDPVE--------------RSLDLTLFYKDKALCG 166

  Fly   451 VMVSLSSPKILTYVLSVASRKFMTTCSEIRLCHNKVLVLDGAHVLGM---------MGCLRAVDL 506
            ...:|:....::.||.:..|:.    .|:     :.|:|||.|:..:         ...|.::.|
  Fly   167 EFFALAESNCMSTVLGIVDREM----PEL-----ERLILDGNHLTNLWVFRKVERRFPRLHSISL 222

  Fly   507 SHNWVQDLSSIHSLGNLPLKSLVLHGNKLCRNYRLPSEYVRAVKEVFPQLTTLDGVDLQTNPG-Q 570
            .||.::::.|:.:|..|||..|.|..|.      ||:.|.:.|.:::|.|..|:.:.:..:|. .
  Fly   223 KHNDIENIYSLRNLQFLPLAELNLLDNP------LPAGYEKEVLDIWPSLQVLNKIQVTPDPAMM 281

  Fly   571 SLQKNFLCDTG 581
            .|.:..|..||
  Fly   282 QLVERVLQHTG 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nxf2	NP_524111.3	leucine-rich repeat	434..474	CDD:275382	9/39 (23%)
		leucine-rich repeat	475..500	CDD:275382	6/33 (18%)
		leucine-rich repeat	501..524	CDD:275382	6/22 (27%)
		leucine-rich repeat	525..555	CDD:275382	8/29 (28%)
		TAP_C	779..841	CDD:197882
nxf4	NP_731156.1	leucine-rich repeat	150..190	CDD:275382	10/57 (18%)
		LRR_4	189..235	CDD:289563	11/50 (22%)
		leucine-rich repeat	191..216	CDD:275382	5/29 (17%)
		leucine-rich repeat	217..240	CDD:275382	6/22 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450005
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3763
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740