Protein Alignment nxf2 and nxf-1

DIOPT Version :9

• Sequence 1: NP_524111.3
• Gene: nxf2 / 39843
• FlyBaseID: FBgn0036640
• Length: 841
• Species: Drosophila melanogaster
• Sequence 2: NP_001129880.1
• Gene: nxf-1 / 191736
• WormBaseID: WBGene00003834
• Length: 609
• Species: Caenorhabditis elegans
• Alignment Length: 558
• Identity: 115/558 - (20%)
• Similarity: 215/558 - (38%)
• Gaps: 114/558 - (20%)

  Fly   349 RLDPTLSNFYPCYYK---------YINTEHVFLVRNCFDQIAHLVNNCNLEMTIPTGDRIFRYYL 404
            :|:..:.||.|..:.         |:..|         |..:.:..|....:...:|.|:..|..
 Worm   100 QLNQIIENFKPLLWTDNARGDFEWYVRDE---------DTASTIRANNRRVVHKESGTRVEFYTS 155

  Fly   405 RMNVSTVKQHHVDPEECIQKAVSQCYVAQNRMLNLERFHSRE--CLKDVMVSLSSPKILTYVLSV 467
            ::....:|... :..|.|.:.|.:.:.|:||:|:|..||..|  ..||:|::|:...::..||..
 Worm   156 KVPAPWMKLKR-EEIEIIHRVVDKRHNAENRVLDLSNFHEDEEFKAKDMMMNLTKGNVMLTVLDH 219

  Fly   468 ASRKFMTTCSEIRLCHNKVLVLDGAHVL-GMMGCLRAVDLSHNWVQDLSSIHSLGNLPLKSLVLH 531
            ...|:....: :.|.:|::..||.|..| .:...:..:|||||.:.....:.....||::.....
 Worm   220 IDDKYGNIVA-LSLSNNRIRHLDYASALVSIAKFVMELDLSHNHISTEKELEKFAGLPVERFFFE 283

  Fly   532 GNKLCRNYRLPSEYVRAVKEVFPQLTTLDGVDLQ---TNPGQSLQKNFLCDTGAYE------LVG 587
            ||.:..::...:.|:..:.:.||:...||||::|   ..|...:........|.|.      ||.
 Worm   284 GNPVVESFTQRAAYISYIHQSFPRCNMLDGVEVQPLVVGPDLDIHDAMPFRAGYYPNPQIRVLVE 348

  Fly   588 AFLENYLREFENDE---FRHNLYKYY-SENSIFTLTCNYNVVQNH----------QTPKILQRLS 638
            .|:.:|...::..:   .|.||:..| ::.|.|:||..:....:|          |...:...:.
 Worm   349 QFVTSYFDFYDGPDGQRTRRNLHNAYDADASTFSLTIEHLRGSSHARHHNDECFAQYAGVSHNVL 413

  Fly   639 KYNRHARNLRNKDYSKASDGVFFGCTYIVEILLQLPRVTH-------DFHSLQTDVMHYNGKGAV 696
            |..|.||:..::....|.|        |...|.:||..:|       |......|::.:..:|
 Worm   414 KQERFARHRASRSARGAMD--------IAVALSKLPTSSHMRDTFIVDVFLQSNDLLGFTVQG-- 468

  Fly   697 IYVAGLLRDEP-PSTRNGHGSKTDIGGVLLGFSRQFVVTFDEANLGLGKRARRLKIANERLHITN 760
            ::..|.|...| ||.                |||.|:|:..|.:        .:.:.:::|.||.
 Worm   469 LFCDGDLTQTPSPSF----------------FSRSFLVSPREND--------SVAVISDQLFITV 509

  Fly   761 PS-----------KTAIRNAFSVNFPDPSERQAEE-----------DSLDVKDHKLLLFQEVTGL 803
            .|           ..:|.|..:|.  ..|..|..:           .:|.:::..:....:.:|:
 Worm   510 ASLDRLEKFKKLYDQSIANGAAVE--QVSAVQIAQIGVNGMGFDGAPALPIREEMIKAMCQFSGM 572

  Fly   804 ISTWVTSIVEEADWDFERALKLFIQKNADHEIPDLAFA 841
            |..:....:.:..|:|:.|.:.|  ......:|..|||
 Worm   573 IPPFSEKCLADCAWNFDFACQKF--NEIKSSVPAEAFA 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nxf2	NP_524111.3	leucine-rich repeat	434..474	CDD:275382	14/41 (34%)
		leucine-rich repeat	475..500	CDD:275382	6/25 (24%)
		leucine-rich repeat	501..524	CDD:275382	5/22 (23%)
		leucine-rich repeat	525..555	CDD:275382	4/29 (14%)
		TAP_C	779..841	CDD:197882	10/72 (14%)
nxf-1	NP_001129880.1	leucine-rich repeat	184..226	CDD:275382	14/41 (34%)
		leucine-rich repeat	227..252	CDD:275382	6/25 (24%)
		leucine-rich repeat	253..276	CDD:275382	5/22 (23%)
		leucine-rich repeat	277..307	CDD:275382	4/29 (14%)
		TAP_C	550..608	CDD:197882	9/59 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D442228at33208
OrthoFinder	1	1.000	-	-		FOG0000862
OrthoInspector	1	1.000	-	-		otm14486
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10662
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R710
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.050