Protein Alignment nxf2 and Nxf7

DIOPT Version :9

• Sequence 1: NP_524111.3
• Gene: nxf2 / 39843
• FlyBaseID: FBgn0036640
• Length: 841
• Species: Drosophila melanogaster
• Sequence 2: NP_570958.1
• Gene: Nxf7 / 170722
• MGIID: 2159343
• Length: 620
• Species: Mus musculus
• Alignment Length: 574
• Identity: 125/574 - (21%)
• Similarity: 224/574 - (39%)
• Gaps: 122/574 - (21%)

  Fly   286 NMLHKIFSPLDVEIDLEVDGARIDTNNMWKLPEFENSQHWHAFMIPDPSHEFNQEVFFDFFFIRL 350
            |.:|.:.|.....:|...|..||    .:.:|:|.     .|..:.|.|::.:.| :|....|.:
Mouse   140 NSIHSLCSVPFTPVDFHCDKHRI----QFFVPDFR-----IASALKDISYKIHNE-YFQKIPIFV 194

  Fly   351 DPTLSNFYPCYYKYINTEHVFLVRNCFDQIAHLVNNCNLEMTIPTGDRIFRYYLRMNVSTVKQHH 415
            :|:::              .:.|:|.|.:  ..:....|.|.       .||.:..:...:|:..
Mouse   195 NPSVA--------------PYSVQNRFTK--EEMEQLKLAMR-------KRYDVSQHALCLKKLR 236

  Fly   416 VDPEECIQKAVSQCYVAQNRMLNLERFHSRECLKDVM--VSLSSPKILTYVLSVASRKFMTTCSE 478
            .||:           :.:|.:..:  .:.|.|:...:  :..:.||:|:
Mouse   237 FDPD-----------LMKNNIHMI--LNHRSCMAATLQIIQENFPKLLS---------------- 272

  Fly   479 IRLCHNKVLVLDG-AHVLGMMGCLRAVDLSHNWVQDLSSIHSLGNLPLKSLVLHGNKLCRNYRLP 542
            :.|..||:..||. ..|:.....|:.::||.|.::.:..:..:..|.|:.|.|.||.||..:...
Mouse   273 LNLSSNKLFQLDSLIDVVKKAPQLKILNLSKNMLRTVWELEKMKGLKLEQLWLEGNPLCSTFPDR 337

  Fly   543 SEYVRAVKEVFPQLTTLDGVDLQTNPGQSLQKN---------FLCDTGAYELVGAFLENYLREFE 598
            |.|:|||.|.||:|:.|||..|......:.|:.         |:........|..||..|...::
Mouse   338 SSYIRAVLECFPELSYLDGRKLLLPTVMNTQERKLMKPCKDIFMGSEVIKNQVHRFLREYYLMYD 402

  Fly   599 NDEFRHNLYKYYSENSIFTLTCNYNVVQNHQTPKILQRLSKYNRHARNLRN-KDYSKASDGVFFG 662
            ::| |..|...|.:.:.|:||..:|     .....|..:..|.:...:::| |::......:.:.
Mouse   403 SEE-RQGLLNIYHDQACFSLTIPFN-----PNDPDLNSMYVYFKDENDMKNFKEFHIQRQLLKYT 461

  Fly   663 CTYIVEILLQLPRVTHDFHSLQTDVMHYNGKGAVIYVAGLLRDEPPSTRNGHGSKTDIGGVLLGF 727
            ...|||.|...|:..|.|.|.|.::...........|.||.::|        |:..:   .:..|
Mouse   462 KQDIVECLRGFPQTLHAFSSFQVNICFQMETMLCFSVCGLFKEE--------GTPKE---CVRAF 515

  Fly   728 SRQFVVTFDEANLGLGKRARRLKIANERLHITNPSKTAIRNAFSVNFPDPSERQAEEDSLDVKDH 792
            .|.|:.....:|         :.|.|::|.:.|||...|.:||.:  |.|:         ...:.
Mouse   516 MRIFIALLGSSN---------MYIVNDQLFVRNPSSEEINSAFVI--PSPT---------SYSNF 560

  Fly   793 KLLLFQE----------VTGLISTWVTSIVEEADWDFERALKLFIQKNADHEIP 836
            ||:|.||          .:|:...|....:|:..||:.||.::|.......:||
Mouse   561 KLVLSQEQQRMVQAFSTQSGMKLEWSQKCLEDNKWDYARAAEVFTMLQTKCKIP 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nxf2	NP_524111.3	leucine-rich repeat	434..474	CDD:275382	6/41 (15%)
		leucine-rich repeat	475..500	CDD:275382	6/25 (24%)
		leucine-rich repeat	501..524	CDD:275382	4/22 (18%)
		leucine-rich repeat	525..555	CDD:275382	14/29 (48%)
		TAP_C	779..841	CDD:197882	15/68 (22%)
Nxf7	NP_570958.1	Tap-RNA_bind	119..201	CDD:370331	16/84 (19%)
		leucine-rich repeat	227..269	CDD:275382	6/54 (11%)
		LRR_8	269..330	CDD:338972	18/76 (24%)
		leucine-rich repeat	270..295	CDD:275382	7/40 (18%)
		leucine-rich repeat	296..319	CDD:275382	4/22 (18%)
		leucine-rich repeat	320..350	CDD:275382	14/29 (48%)
		NTF2_like	393..539	CDD:385413	36/171 (21%)
		TAP_C	558..619	CDD:197882	15/57 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837911
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3763
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D442228at33208
OrthoFinder	1	1.000	-	-		FOG0000862
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.810