Protein Alignment mbf1 and EDF1

DIOPT Version :9

• Sequence 1: NP_001261952.1
• Gene: mbf1 / 39842
• FlyBaseID: FBgn0262732
• Length: 188
• Species: Drosophila melanogaster
• Sequence 2: NP_003783.1
• Gene: EDF1 / 8721
• HGNCID: 3164
• Length: 148
• Species: Homo sapiens
• Alignment Length: 138
• Identity: 91/138 - (65%)
• Similarity: 115/138 - (83%)
• Gaps: 0/138 - (0%)

  Fly     2 SDWDSVTVLRKKAPKSSTLKTESAVNQARRQGVAVDTQQKYGAGTNKQHVTTKNTAKLDRETEEL 66
            ||||:|||||||.|.::..|::.|:..|:|:|..|:|.:|:.||.||||..||||||||||||||
Human     4 SDWDTVTVLRKKGPTAAQAKSKQAILAAQRRGEDVETSKKWAAGQNKQHSITKNTAKLDRETEEL 68

  Fly    67 RHDKIPLDVGKLIQQGRQSKGLSQKDLATKICEKQQVVTDYEAGRGIPNNLILGKMERVLGIKLR 131
            .||::.|:|||:||||||||||:||||||||.||.||:.|||:||.||||.:|||:||.:|:|||
Human    69 HHDRVTLEVGKVIQQGRQSKGLTQKDLATKINEKPQVIADYESGRAIPNNQVLGKIERAIGLKLR 133

  Fly   132 GKERGQPI 139
            ||:.|:||
Human   134 GKDIGKPI 141

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mbf1	NP_001261952.1	MBF1	2..70	CDD:285695	41/67 (61%)
		aMBF1	12..144	CDD:224726	82/128 (64%)
		HTH_3	79..131	CDD:279690	38/51 (75%)
EDF1	NP_003783.1	MBF1	5..71	CDD:400707	39/65 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	33..66		21/32 (66%)
		Interaction with NR5A2, PPARG and NR1H3. /evidence=ECO:0000269|PubMed:12040021	37..113		54/75 (72%)
		aMBF1	<48..142	CDD:331548	69/94 (73%)
		Interaction with TBP and NR5A1. /evidence=ECO:0000269|PubMed:10567391	69..108		28/38 (74%)
		IQ motif	81..88		6/6 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160390
Domainoid	1	1.000	92	1.000	Domainoid score	I7657
eggNOG	1	0.900	-	-		E1_COG1813
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2809
Inparanoid	1	1.050	191	1.000	Inparanoid score	I3883
Isobase	1	0.950	-	0	Normalized mean entropy	S462
OMA	1	1.010	-	-		QHG54797
OrthoDB	1	1.010	-	-		D1571466at2759
OrthoFinder	1	1.000	-	-		FOG0003409
OrthoInspector	1	1.000	-	-		oto91533
orthoMCL	1	0.900	-	-		OOG6_102239
Panther	1	1.100	-	-	LDO	PTHR10245
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R686
SonicParanoid	1	1.000	-	-		X2304
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750