DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mbf1 and Edf1

DIOPT Version :9

Sequence 1:	NP_001261952.1	Gene:	mbf1 / 39842	FlyBaseID:	FBgn0262732	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	XP_030107780.1	Gene:	Edf1 / 59022	MGIID:	1891227	Length:	154	Species:	Mus musculus

Alignment Length:	178	Identity:	76/178 - (42%)
Similarity:	99/178 - (55%)	Gaps:	46/178 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SDWDSVTVLRKKAPKSSTLKTESAVNQARRQGVAVDTQQKYGAGTNKQHVTTKNTAKLDRETEEL 66
            ||||:|||||||.|.::..|::.|:..|:|:|..|:|.:|:.||.||||..||||||||||||||
Mouse     4 SDWDTVTVLRKKGPTAAQAKSKQAILAAQRRGEDVETSKKWAAGQNKQHSITKNTAKLDRETEEL 68

  Fly    67 RHDKIPLDVGKLIQQGRQSKGLSQKDLATKICEKQQVVTDYEAGRGIPNNLILGKMERVLGIKLR 131
            .||::.|:|||:||:|||||||:||||||         .....||      ..|.:.|      |
Mouse    69 HHDRVTLEVGKVIQRGRQSKGLTQKDLAT---------ASSSGGR------TSGSLSR------R 112

  Fly   132 GKERGQ-----PIAPPGKKXNDAAASAASGAPHTVTSGRSARQQNHQH 174
            |:.|.:     |:.|         |..:...|           |:|||
Mouse   113 GRRRNEHKASKPVVP---------AELSWLVP-----------QDHQH 140

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mbf1	NP_001261952.1	MBF1	2..70	CDD:285695	41/67 (61%)
		aMBF1	12..144	CDD:224726	61/136 (45%)
		HTH_3	79..131	CDD:279690	19/51 (37%)
Edf1	XP_030107780.1	MBF1	4..72	CDD:369924	41/67 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850745
Domainoid	1	1.000	92	1.000	Domainoid score	I7612
eggNOG	1	0.900	-	-		E1_COG1813
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2809
Inparanoid	1	1.050	190	1.000	Inparanoid score	I3874
Isobase	1	0.950	-	0	Normalized mean entropy	S462
OMA	1	1.010	-	-		QHG54797
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003409
OrthoInspector	1	1.000	-	-		oto95114
orthoMCL	1	0.900	-	-		OOG6_102239
Panther	1	1.100	-	-	LDO	PTHR10245
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R686
SonicParanoid	1	1.000	-	-		X2304
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740