DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mipp1 and PHO11

DIOPT Version :9

Sequence 1:	NP_001287082.1	Gene:	Mipp1 / 39841	FlyBaseID:	FBgn0026061	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_009434.1	Gene:	PHO11 / 851299	SGDID:	S000000094	Length:	467	Species:	Saccharomyces cerevisiae

Alignment Length:	487	Identity:	103/487 - (21%)
Similarity:	167/487 - (34%)	Gaps:	137/487 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 LQTRQFSSKTAYQIVKGT-------DIDK----------------QYLVPG-----------CQP 58
            |::..:|...|..:..||       ||||                .|..||           |:.
Yeast     2 LKSAVYSILAASLVNAGTIPLGKLSDIDKIGTQTEIFPFLGGSGPYYSFPGDYGISRDLPESCEM 66

  Fly    59 QKMWIFHRHGTRLPKKS-----------MINKASRVAELRDLIINNYQ--VARTKP-ETDALCQT 109
            :::.:..|||.|.|..|           :.|...:.:.....:.::|:  :..||. |.:.....
Yeast    67 KQVQMVGRHGERYPTVSKAKSIMTTWYKLSNYTGQFSGALSFLNDDYEFFIRDTKNLEMETTLAN 131

  Fly   110 DLIAIKLWKWNSSITPDMEEYLTAQGY--EDLRGTAKLYQRYYPTVLTANYN---DTYYQF---- 165
            .:..:..:....:......::|...||  |:....|         |.|:|.|   ||...|
Yeast   132 SVNVLNPYTGEMNAKRHARDFLAQYGYMVENQTSFA---------VFTSNSNRCHDTAQYFIDGL 187

  Fly   166 ---RHTDTQRTTESFKAFAEGLFGSQNAAHPVEIPKQDL---LLRPYD--YCSSF-KNVNYKDEG 221
               .:...|..:|:..|.|..|    :|.|.......|:   :|:.||  |.|.. |.:|.:::|
Yeast   188 GDKFNISLQTISEAESAGANTL----SAHHSCPAWDDDVNDDILKKYDTKYLSGIAKRLNKENKG 248

  Fly   222 SEYYKFHQSKLYNDTLADISTRLGFLYTLEEADIKLMYDMCRYEQAWNVDRNSVWCGAFLPEQIT 286
                                      ..|..:|....:..|.||  .|....|..|..|..:::.
Yeast   249 --------------------------LNLTSSDANTFFAWCAYE--INARGYSDICNIFTKDELV 285

  Fly   287 VFEYLEDLKYYYGSGYGFPENAHLNCRL------------VQDLLTHLSNPVSPHVVAHFGHSTG 339
            .|.|.:||:.||.:|.|:.....:...|            |||....||          |.|.|.
Yeast   286 RFSYGQDLETYYQTGPGYDVVRSVGANLFNASVKLLKESEVQDQKVWLS----------FTHDTD 340

  Fly   340 LLTLLTALGIQKDDIKLRADNYDSLTSRRWKSSLIDPFAANFVAVKYDCPADLDREKVVFFLNQQ 404
            :|..||.:||..|...|.|::...:.:...:|..: |..|.....|:.|..|   ..|.:.:|..
Yeast   341 ILNYLTTIGIIDDKNNLTAEHVPFMENTFHRSWYV-PQGARVYTEKFQCSND---TYVRYVINDA 401

  Fly   405 AVQLDWCSVG---LCKWSDVLE-KYKTIADAD 432
            .|.::.||.|   .|:.:|..: ..|.:|..|
Yeast   402 VVPIETCSTGPGFSCEINDFYDYAEKRVAGTD 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mipp1	NP_001287082.1	HP_HAP_like	129..402	CDD:132717	69/302 (23%)
PHO11	NP_009434.1	His_Phos_2	65..399	CDD:395259	80/388 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346144
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1382
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5846
OMA	1	1.010	-	-		QHG55377
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101372
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.600