DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mipp1 and RGD1564801

DIOPT Version :9

Sequence 1:	NP_001287082.1	Gene:	Mipp1 / 39841	FlyBaseID:	FBgn0026061	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_038956737.1	Gene:	RGD1564801 / 499084	RGDID:	1564801	Length:	481	Species:	Rattus norvegicus

Alignment Length:	442	Identity:	115/442 - (26%)
Similarity:	186/442 - (42%)	Gaps:	57/442 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 FSSKTAYQIVK----GTDI----DKQYLVPGCQPQKMWIFHRHGTRLPKKSMINKASRVAELRDL 89
            |.:||.|:.|.    |..:    |.:.|...|.|.::....|||||.|....|.|   :.:|:.|
  Rat    47 FGTKTRYEDVNPWLLGDPVAPRRDPELLAGTCTPVQLVALIRHGTRYPTTKQIRK---LRQLQGL 108

  Fly    90 IINNYQVARTKPETDALCQTDLIAIKLWKWNSSITPDMEEYLTAQGYEDLRGTAKLYQRYYPTVL 154
            :       :|:...|.   ...:|..|.:|.......|:..|..:|.:|:|..|......:|.:.
  Rat   109 L-------QTRESVDG---GSRVAAALDQWPLWYDDWMDGQLVEKGRQDMRQLALRLAALFPDLF 163

  Fly   155 TANYNDTYYQFR--HTDTQRTTESFKAFAEGLFGSQNAAHP--------VEIPK-QDLLLRPYDY 208
            .   .:.|.:.|  .:......:|..||.:||:...:...|        .:.|: .|.|:|.:|:
  Rat   164 C---QEKYGRLRLITSSKHHCVDSSAAFLQGLWQHYHPGLPPPDVSDMECDPPRVNDKLMRFFDH 225

  Fly   209 CSSFKNVNYKDEGSEYY--KFHQSKLYNDTLADISTRLGFLYTLEEAD-IKLMYDMCRYEQAWNV 270
            |..|.....::..:.|:  .|.........|..::..|........|| |::.:..|.::.|..
  Rat   226 CEKFLTEVERNATALYHVEAFKTGPEMQTVLKKVAATLQVPVNNLNADLIQVAFFTCSFDLAVQ- 289

  Fly   271 DRNSVWCGAFLPEQITVFEYLEDLKYYYGSGYGFPENAHLNCRLVQDLLTHL---------SNPV 326
            ..:|.||..|..:...|.|||.|||.|:...||:..|:..:|.|.||:..||         |.||
  Rat   290 GVHSPWCDVFDVDDAKVLEYLNDLKQYWKRSYGYAINSRSSCNLFQDIFLHLDKAVEQKQRSQPV 354

  Fly   327 SPHVVAHFGHSTGLLTLLTALGIQKDDIKLRADNYDSLTSRRWKSSLIDPFAANFVAVKYDC-PA 390
            |..|:..|||...||.||:.:|..||...|.|.|::....|.::|..|.|:|:|.:.|.|.| .|
  Rat   355 SSPVILQFGHEETLLPLLSLMGYFKDKEPLTAYNFEEQVHREFRSGHIVPYASNLIFVLYHCEDA 419

  Fly   391 DLDREK--VVFFLNQQAVQLDWCSVGLCKWSDVLEKYKTIADADCGEYYCRT 440
            ...:||  :...||::.:.|......:..:.|:...|:.|..:      |:|
  Rat   420 QTPQEKFQIQMLLNEKVLPLAHSQKTVALYEDLKNHYQDILQS------CQT 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mipp1	NP_001287082.1	HP_HAP_like	129..402	CDD:132717	81/298 (27%)
RGD1564801	XP_038956737.1	HP_HAP_like	82..429	CDD:132717	97/363 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352923
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55377
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004136
OrthoInspector	1	1.000	-	-		mtm8917
orthoMCL	1	0.900	-	-		OOG6_101372
Panther	1	1.100	-	-	O	PTHR20963
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3401
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.850