DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mipp1 and minpp1

DIOPT Version :9

Sequence 1:	NP_001287082.1	Gene:	Mipp1 / 39841	FlyBaseID:	FBgn0026061	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_002935472.2	Gene:	minpp1 / 100493648	XenbaseID:	XB-GENE-952972	Length:	483	Species:	Xenopus tropicalis

Alignment Length:	440	Identity:	127/440 - (28%)
Similarity:	195/440 - (44%)	Gaps:	58/440 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 TRQFSSKTAYQIVKGTDIDKQYLVPG--------CQPQKMWIFHRHGTRLPKKSMINKASRVAEL 86
            |..|.:||.|:.|....::...||.|        |.|.|:....|||||.|....|.|   :.::
Frog    42 TFYFGTKTRYEEVNPFLLENPLLVTGKQDLLPNMCTPIKIVSVIRHGTRYPTHKQIKK---MKKM 103

  Fly    87 RDLIINNYQVARTKPETDALCQTDLIAIKLWKWNSSITPDMEEYLTAQGYEDLRGTAKLYQRYYP 151
            .|||:....:           :::|:. :|.:|:......|:..|..:|.:|:...|......:|
Frog   104 HDLIVRQEGI-----------RSELVE-ELQRWDMWYEDWMDGQLVKKGEQDMSNLAYRLASLFP 156

  Fly   152 TVLTAN-YNDTYYQFRHTDTQRTTESFKAFAEGL----FGSQNAAHP-------VEIPKQDLLLR 204
            ::.|.: .......|..:...|..:|.|:|..||    ||...|...       :|....|.|:|
Frog   157 SLFTKDRLKQNNMTFTTSSKHRCVDSTKSFISGLVHDYFGFPQAPESELKDLPYMEPVINDHLMR 221

  Fly   205 PYDYCSSF-KNVNYKDEG-SEYYKFHQSKLYNDTLADISTRLGFLYTLEEAD-----IKLMYDMC 262
            .:|:|..| ..|...|.. .|..||.||......:..|:|    |..:.|.|     |::.:.:|
Frog   222 FFDHCPKFLAEVEDNDTALHEVDKFKQSPEMRKVINKIAT----LLDVPELDLSADLIQMAFFIC 282

  Fly   263 RYEQAWNVDRNSVWCGAFLPEQITVFEYLEDLKYYYGSGYGFPENAHLNCRLVQDLLTHL----- 322
            .:|.|.....:|.||..|..|...|.|||.|||.|:..|:|:..|:..:|.|.|.:..||
Frog   283 SFELAIKNITDSPWCNLFDQEDARVLEYLNDLKQYWKRGHGYDINSRSSCHLFQHIFQHLEAAVT 347

  Fly   323 ----SNPVSPHVVAHFGHSTGLLTLLTALGIQKDDIKLRADNYDSLTSRRWKSSLIDPFAANFVA 383
                |..||..||..|||:..||.||..||:.||:..|.|:|:.|.:.|:::|..|.|:|:|...
Frog   348 ESKSSQQVSMPVVMQFGHAETLLPLLALLGLFKDETPLTAENFISQSERKFRSGHIVPYASNLAF 412

  Fly   384 VKYDCP-ADLDREK--VVFFLNQQAVQLDWCSVGLCKWSDVLEKYKTIAD 430
            |.:.|. |:..||:  |...||:|.:........||.:.::.|:|..:.|
Frog   413 VLHRCDMAETPRERYQVQLLLNEQLLHFPHSHNSLCLFDEMKEQYGHLLD 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mipp1	NP_001287082.1	HP_HAP_like	129..402	CDD:132717	92/303 (30%)
minpp1	XP_002935472.2	HP	82..434	CDD:416258	107/370 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55377
OrthoDB	1	1.010	-	-		D1046588at2759
OrthoFinder	1	1.000	-	-		FOG0004136
OrthoInspector	1	1.000	-	-		otm47486
Panther	1	1.100	-	-	LDO	PTHR20963
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3401
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.030