Protein Alignment LIMK1 and Limk1

DIOPT Version :10

• Sequence 1: NP_002305.1
• Gene: LIMK1 / 3984
• HGNCID: 6613
• Length: 647
• Species: Homo sapiens
• Sequence 2: NP_113915.2
• Gene: Limk1 / 65172
• RGDID: 62055
• Length: 647
• Species: Rattus norvegicus
• Alignment Length: 647
• Identity: 617/647 - (95%)
• Similarity: 628/647 - (97%)
• Gaps: 0/647 - (0%)

Human     1 MRLTLLCCTWREERMGEEGSELPVCASCGQRIYDGQYLQALNADWHADCFRCCDCSASLSHQYYE 65
            ||||||||||||||||||||||||||||.|.||||||||||||||||||||||:||.||||||||
  Rat     1 MRLTLLCCTWREERMGEEGSELPVCASCSQSIYDGQYLQALNADWHADCFRCCECSTSLSHQYYE 65

Human    66 KDGQLFCKKDYWARYGESCHGCSEQITKGLVMVAGELKYHPECFICLTCGTFIGDGDTYTLVEHS 130
            ||||||||||||||||||||||||.||||||||||||||||||||||.||.||||||||||||||
  Rat    66 KDGQLFCKKDYWARYGESCHGCSEHITKGLVMVAGELKYHPECFICLACGNFIGDGDTYTLVEHS 130

Human   131 KLYCGHCYYQTVVTPVIEQILPDSPGSHLPHTVTLVSIPASSHGKRGLSVSIDPPHGPPGCGTEH 195
            |||||.|||||||||||||||||||||||||||||||||||:|||||||||||||||||||||||
  Rat   131 KLYCGQCYYQTVVTPVIEQILPDSPGSHLPHTVTLVSIPASAHGKRGLSVSIDPPHGPPGCGTEH 195

Human   196 SHTVRVQGVDPGCMSPDVKNSIHVGDRILEINGTPIRNVPLDEIDLLIQETSRLLQLTLEHDPHD 260
            |||||||||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||
  Rat   196 SHTVRVQGVDPGCMSPDVKNSIHIGDRILEINGTPIRNVPLDEIDLLIQETSRLLQLTLEHDPHD 260

Human   261 TLGHGLGPETSPLSSPAYTPSGEAGSSARQKPVLRSCSIDRSPGAGSLGSPASQRKDLGRSESLR 325
            :||||...:.|||:||.:||||:|||||||||||||||||.|||||||.||||||||||||||||
  Rat   261 SLGHGPVSDPSPLASPVHTPSGQAGSSARQKPVLRSCSIDTSPGAGSLVSPASQRKDLGRSESLR 325

Human   326 VVCRPHRIFRPSDLIHGEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRC 390
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   326 VVCRPHRIFRPSDLIHGEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRC 390

Human   391 LEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMN 455
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   391 LEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMN 455

Human   456 IIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEM 520
            ||||||||||||||||:|||||||||||||:|||.|.|.||||||||||||||||||||||||||
  Rat   456 IIHRDLNSHNCLVRENRNVVVADFGLARLMIDEKGQSEDLRSLKKPDRKKRYTVVGNPYWMAPEM 520

Human   521 INGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVR 585
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   521 INGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVR 585

Human   586 CCDLDPEKRPSFVKLEHWLETLRMHLAGHLPLGPQLEQLDRGFWETYRRGESGLPAHPEVPD 647
            ||||||||||||||||.||||||||||||||||||||||:||||||||||||.|||||||||
  Rat   586 CCDLDPEKRPSFVKLEQWLETLRMHLAGHLPLGPQLEQLERGFWETYRRGESSLPAHPEVPD 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LIMK1	NP_002305.1	LIM1_LIMK1	5..77	CDD:188846	67/71 (94%)
		LIM	84..138	CDD:413332	49/53 (92%)
		PDZ_LIMK-like	160..258	CDD:467236	95/97 (98%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	260..319		46/58 (79%)
		STKc_LIMK1	345..611	CDD:271123	259/265 (98%)
Limk1	NP_113915.2	LIM1_LIMK1	5..77	CDD:188846	67/71 (94%)
		LIM2_LIMK1	84..138	CDD:188848	49/53 (92%)
		PDZ_LIMK-like	160..258	CDD:467236	95/97 (98%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	256..316		47/59 (80%)
		STKc_LIMK1	345..611	CDD:271123	259/265 (98%)