Protein Alignment LIMK1 and Limk1

DIOPT Version :10

• Sequence 1: NP_002305.1
• Gene: LIMK1 / 3984
• HGNCID: 6613
• Length: 647
• Species: Homo sapiens
• Sequence 2: XP_036020724.1
• Gene: Limk1 / 16885
• MGIID: 104572
• Length: 702
• Species: Mus musculus
• Alignment Length: 702
• Identity: 616/702 - (87%)
• Similarity: 627/702 - (89%)
• Gaps: 55/702 - (7%)

Human     1 MRLTLLCCTWREERMGEEGSELPVCASCGQRIYDGQYLQALNADWHADCFRCCDCSASLSHQYYE 65
            |||||||||||||||||||||||||||||||||||||||||||||||||||||:||.||||||||
Mouse     1 MRLTLLCCTWREERMGEEGSELPVCASCGQRIYDGQYLQALNADWHADCFRCCECSVSLSHQYYE 65

Human    66 KDGQLFCKKDYWARYGESCHGCSEQITKGLVMVAGELKYHPECFICLTCGTFIGDGDTYTLVEHS 130
            ||||||||||||||||||||||||.||||||||||||||||||||||.||.||||||||||||||
Mouse    66 KDGQLFCKKDYWARYGESCHGCSEHITKGLVMVAGELKYHPECFICLACGNFIGDGDTYTLVEHS 130

Human   131 KLYCGHCYYQTVVTPVIEQILPDSPGSHLPHTVTLVSIPASSHGKRGLSVSIDPPHGPPGCGTEH 195
            |||||.|||||||||||||||||||||||||||||||||||:|||||||||||||||||||||||
Mouse   131 KLYCGQCYYQTVVTPVIEQILPDSPGSHLPHTVTLVSIPASAHGKRGLSVSIDPPHGPPGCGTEH 195

Human   196 SHTVRVQGVDPGCMSPDVKNSIHVGDRILEINGTPIRNVPLDEIDLLIQETSRLLQLTLEHDPHD 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   196 SHTVRVQGVDPGCMSPDVKNSIHVGDRILEINGTPIRNVPLDEIDLLIQETSRLLQLTLEHDPHD 260

Human   261 TLGHGLGPETSPLSSPAYTPSGEAGSSARQKPVLRSCSIDRSPGAGSLGSPASQRKDLGRSESLR 325
            :||||...:.||||||.:||||:|.|||||||||||||||.|||..||.||||||||||||||||
Mouse   261 SLGHGPVSDPSPLSSPVHTPSGQAASSARQKPVLRSCSIDTSPGTSSLASPASQRKDLGRSESLR 325

Human   326 VVCRPHRIFRPSDLIHGEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRC 390
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   326 VVCRPHRIFRPSDLIHGEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRC 390

Human   391 LEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMN 455
            ||||||||||||||||||||||||||||||||||||:||||||||||||||||||||||||||||
Mouse   391 LEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKNMDSQYPWSQRVSFAKDIASGMAYLHSMN 455

Human   456 IIHRDLNSHNCLVRE-------------------------------------------------- 470
            |||||||||||||||
Mouse   456 IIHRDLNSHNCLVREPSQTPPEVAQATQAAATTATVCGQGHLGRLLELETWQRHVRGGQEDKRQS 520

Human   471 -----NKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKV 530
                 |:|||||||||||||:|||.|.|.||||||||||||||||||||||||||||||||||||
Mouse   521 APSLQNRNVVVADFGLARLMIDEKNQSEDLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKV 585

Human   531 DVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRP 595
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   586 DVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRP 650

Human   596 SFVKLEHWLETLRMHLAGHLPLGPQLEQLDRGFWETYRRGESGLPAHPEVPD 647
            ||||||.|||||||||:||||||||||||:||||||||||||.|||||||||
Mouse   651 SFVKLEQWLETLRMHLSGHLPLGPQLEQLERGFWETYRRGESSLPAHPEVPD 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LIMK1	NP_002305.1	LIM1_LIMK1	5..77	CDD:188846	69/71 (97%)
		LIM	84..138	CDD:413332	49/53 (92%)
		PDZ_LIMK-like	160..258	CDD:467236	96/97 (99%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	260..319		44/58 (76%)
		STKc_LIMK1	345..611	CDD:271123	258/320 (81%)
Limk1	XP_036020724.1	LIM1_LIMK1	5..77	CDD:188846	69/71 (97%)
		LIM2_LIMK1	84..138	CDD:188848	49/53 (92%)
		PDZ_LIMK-like	160..258	CDD:467236	96/97 (99%)
		STKc_LIMK1	345..666	CDD:271123	258/320 (81%)