Protein Alignment st and PDR12

DIOPT Version :9

• Sequence 1: NP_524108.1
• Gene: st / 39836
• FlyBaseID: FBgn0003515
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_015267.1
• Gene: PDR12 / 856049
• SGDID: S000005979
• Length: 1511
• Species: Saccharomyces cerevisiae
• Alignment Length: 758
• Identity: 179/758 - (23%)
• Similarity: 294/758 - (38%)
• Gaps: 207/758 - (27%)

  Fly     1 MSDSDSKRIDVEAPERVEQHELQVMPVGSTIEVPSLDSTPKLSKR-----NSSERSLPLRSYSKW 60
            |.:..::..|.....|.|..|        .:..|::|....::::     |..:.::|.
Yeast   803 MPELGTENADARTASREEMME--------ALNGPNVDLEKVIAEKDVFTWNHLDYTIPY------ 853

  Fly    61 SPTEQGATLVWRDLCVYTNVGGSGQRMKRIINNSTGAIQPGTLMALMGSSGSGKTTLMSTLAFRQ 125
                .|||                   ::::::..|.::||.:.||||.||:|||||::.||.|.
Yeast   854 ----DGAT-------------------RKLLSDVFGYVKPGKMTALMGESGAGKTTLLNVLAQRI 895

  Fly   126 PAGTVVQGDILINGRRIGPFMHRISGYVYQDDLFLGSLTVLEHLNFMAHLRLDRRVSKEERRLII 190
            ..| |:.||:|:|.:.:....:|..|||.|.|..:..|:|.|.|.|.|.||....|..||:...:
Yeast   896 NMG-VITGDMLVNAKPLPASFNRSCGYVAQADNHMAELSVRESLRFAAELRQQSSVPLEEKYEYV 959

  Fly   191 KELLERTGLLSAAQTRIGSGDDKKVLSGGERKRLAFAVELLNNP-VILFCDEPTTGLDSYSAQQL 254
            ::::...|:.:.|:..:|.  ..:.|:..:||:|:..|||:..| ::||.||||:||||.||..:
Yeast   960 EKIITLLGMQNYAEALVGK--TGRGLNVEQRKKLSIGVELVAKPSLLLFLDEPTSGLDSQSAWSI 1022

  Fly   255 VATLYELAQKGTTILCTIHQPSSQLFDNFNNVMLL-ADGRVAFTG----SPQHALSFFANH-GYY 313
            |..:..||..|.:|||||||||:.||:.|:.::|| ..|::.:.|    :.:..|.:|... |..
Yeast  1023 VQFMRALADSGQSILCTIHQPSATLFEQFDRLLLLKKGGKMVYFGDIGPNSETLLKYFERQSGMK 1087

  Fly   314 CPEAYNPADFL---IGVLATDPGYEQASQRSAQHLCDQFAVS--SAAKQRDMLVNLEIHMAQSGN 373
            |..:.|||:::   ||..||      ||..|..|  |.:..|  .||.:.::   .|:|....|.
Yeast  1088 CGVSENPAEYILNCIGAGAT------ASVNSDWH--DLWLASPECAAARAEV---EELHRTLPGR 1141

  Fly   374 -FPFDTEVESFRGVAWYKRFHVVWLRASLTLLRDPTIQWLRFIQKIAMAFIIGACFAGTTEPSQL 437
             ...|.|:.:....::..:...|..|.:|...|.|.....:|.:.:|.|..:|..:.|.......
Yeast  1142 AVNDDPELATRFAASYMTQIKCVLRRTALQFWRSPVYIRAKFFECVACALFVGLSYVGVNHSVGG 1206

  Fly   438 GVQAVQGALFIMI-------------------------SENTYHPMYSVLNLFPQGFPLFMRETR 477
            .::|......:::                         :.||:|  :|||        |......
Yeast  1207 AIEAFSSIFMLLLIALAMINQLHVFAYDSRELYEVREAASNTFH--WSVL--------LLCHAAV 1261

  Fly   478 SGLYSTGQYYAANILALLPG----------------MIIEPLIFVIICYWL----------TGLR 516
            ...:||...:...|....|.                ::|.||.||....|:          :.:.
Yeast  1262 ENFWSTLCQFMCFICYYWPAQFSGRASHAGFFFFFYVLIFPLYFVTYGLWILYMSPDVPSASMIN 1326

  Fly   517 STFYA------------------------------FGVTAMCVVLVMNVATACGCFFSTAFNSVP 551
            |..:|                              :.|.|:...||.|....|.
Yeast  1327 SNLFAAMLLFCGILQPREKMPAFWRRLMYNVSPFTYVVQALVTPLVHNKKVVCN----------- 1380

  Fly   552 LAMAYLVPLDYIFMITSGIFIQVNSLPVAFWWTQFLSWMLYANEAMTAAQWSGVQNITCFQESAD 616
                   |.:|..|          ..|......:|||..:..|...       :.|.|..:....
Yeast  1381 -------PHEYNIM----------DPPSGKTCGEFLSTYMDNNTGY-------LVNPTATENCQY 1421

  Fly   617 LPCFHTGQD-VLDKYSFNESNVYRNLLAMVGLYFGFHLLGYYC 658
            .|  :|.|| |:.||:....:.:||        ||| :..|.|
Yeast  1422 CP--YTVQDQVVAKYNVKWDHRWRN--------FGF-MWAYIC 1453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	ABCG_EPDR	66..298	CDD:213180	85/233 (36%)
		3a01204	67..665	CDD:273361	169/687 (25%)
		ABC2_membrane	395..600	CDD:279410	44/285 (15%)
PDR12	NP_015267.1	3a01205	89..1468	CDD:273362	179/758 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341552
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13430
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
TreeFam	0	0.000	Not matched by this tool.
	4	3.840