DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment st and ABCG10

DIOPT Version :9

Sequence 1:	NP_524108.1	Gene:	st / 39836	FlyBaseID:	FBgn0003515	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_175734.1	Gene:	ABCG10 / 841761	AraportID:	AT1G53270	Length:	590	Species:	Arabidopsis thaliana

Alignment Length:	602	Identity:	165/602 - (27%)
Similarity:	278/602 - (46%)	Gaps:	68/602 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 YTNVGG--SGQRMKRIINNSTGAIQPGTLMALMGSSGSGKTTLMSTLAFRQPAGTVVQGDILING 139
            ::|:.|  |.:..|.|:.:.:...:...:.|:.|.||:|||||:..||.:...|. |.|.:|:||
plant    35 FSNLCGLLSEKEEKVILKDVSCDARSAEITAIAGPSGAGKTTLLEILAGKVSHGK-VSGQVLVNG 98

  Fly   140 RRI-GPFMHRISGYVYQDDLFLGSLTVLEHLNFMAHLRLDRRVSKEERRLIIKELLERTGLLSAA 203
            |.: ||...|:||:|.|:|.....|||.|.|.:.|.|||  :..:::....:|.|::..||...|
plant    99 RPMDGPEYRRVSGFVPQEDALFPFLTVQETLTYSALLRL--KTKRKDAAAKVKRLIQELGLEHVA 161

  Fly   204 QTRIGSGDDKKVLSGGERKRLAFAVELLNNPVILFCDEPTTGLDSYSAQQLVATLYELA-QKGTT 267
            .:|||.| .:..:|||||:|::..|||:::|.::..||||:||||.||.|:|..|.::. ::|.|
plant   162 DSRIGQG-SRSGISGGERRRVSIGVELVHDPNVILIDEPTSGLDSASALQVVTLLKDMTIKQGKT 225

  Fly   268 ILCTIHQPSSQLFDNFNNVMLLADGRVAFTGSPQHALSFFANHGYYCPEAYNPADFLIGVLATDP 332
            |:.|||||..::.:..:.::||::|.|...||...........|:..|...|..::.|.:..:
plant   226 IVLTIHQPGFRILEQIDRIVLLSNGMVVQNGSVYSLHQKIKFSGHQIPRRVNVLEYAIDIAGS-- 288

  Fly   333 GYEQASQRSAQHL-CDQFAVSSAAKQRDMLVNLEIHMAQSGNFPFDTEVESFRGVAWYKRFHVVW 396
             .|....:|.:.: |  :..|...|...:....|:|.:.|.:.....||:            ::.
plant   289 -LEPIRTQSCREISC--YGHSKTWKSCYISAGGELHQSDSHSNSVLEEVQ------------ILG 338

  Fly   397 LRASLTLLRDPTIQWLRFIQKIAMAFIIGACFAGTTEPSQLGVQAVQGALFIMISENTYHPMYSV 461
            .|:...:.|...:...|.:|......|:|:.:.......: ..:.::...|..|       :..:
plant   339 QRSCKNIFRTKQLFTTRALQASIAGLILGSIYLNVGNQKK-EAKVLRTGFFAFI-------LTFL 395

  Fly   462 LNLFPQGFPLF-------MRETRSGLYSTGQYYAANILALLPGMIIEPLIFVIICYWLTGLR--- 516
            |:...:|.|:|       ||||....|....|..|:.|..:|.::|..::|....|||.|||
plant   396 LSSTTEGLPIFLQDRRILMRETSRRAYRVLSYVLADTLIFIPFLLIISMLFATPVYWLVGLRREL 460

  Fly   517 STFYAFGVTAMCVVLVMNVATACGCFFSTAFNSVPLAMAYLVPLDYIFMITSGIFIQVNSLPVAF 581
            ..|..|.:....|:|:.|...||   ||....:..:..:.:..|...|.:.||.||..:.:||.:
plant   461 DGFLYFSLVIWIVLLMSNSFVAC---FSALVPNFIMGTSVISGLMGSFFLFSGYFIAKDRIPVYW 522

  Fly   582 WWTQFLSWMLYANEAMTAAQWSGVQNITCFQESADLPCFHTGQDV-LDKYSFNESNVYRNLLAMV 645
            .:..:||...|..|.:...::.|                    || |.:....||..:.||..|.
plant   523 EFMHYLSLFKYPFECLMINEYRG--------------------DVFLKQQDLKESQKWSNLGIMA 567

  Fly   646 GLYFGFHLLGYYCLWRR 662
            ....|:.:||::.||.|
plant   568 SFIVGYRVLGFFILWYR 584

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	ABCG_EPDR	66..298	CDD:213180	84/224 (38%)
		3a01204	67..665	CDD:273361	165/602 (27%)
		ABC2_membrane	395..600	CDD:279410	50/214 (23%)
ABCG10	NP_175734.1	3a01204	27..589	CDD:273361	165/602 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.880