DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment st and ABCG13

DIOPT Version :9

Sequence 1:	NP_524108.1	Gene:	st / 39836	FlyBaseID:	FBgn0003515	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_175557.1	Gene:	ABCG13 / 841571	AraportID:	AT1G51460	Length:	678	Species:	Arabidopsis thaliana

Alignment Length:	599	Identity:	167/599 - (27%)
Similarity:	278/599 - (46%)	Gaps:	101/599 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 TEQGATLV-WRDLCVYTNVGGSGQRMKRIINNSTGAIQPGTLMALMGSSGSGKTTLMSTLAFRQP 126
            |.:||..| |.||.|.....|.| ..||::|...|..:|..::|:||.|||||:||:..||.|..
plant     3 TPEGAMYVAWEDLTVVIPNFGEG-ATKRLLNGVNGCGEPNRILAIMGPSGSGKSTLLDALAGRLA 66

  Fly   127 AGTVVQGDILINGRRIGPFMHRI----SGYVYQDDLFLGSLTVLEHLNFMAHLRLDRRVSKEERR 187
            ...|:.|.:|:||::     .|:    :.||.|:|:.||:|||.|.:::.|||||..::::||..
plant    67 GNVVMSGKVLVNGKK-----RRLDFGAAAYVTQEDVLLGTLTVRESISYSAHLRLPSKLTREEIS 126

  Fly   188 LIIKELLERTGLLSAAQTRIGSGDDKKVLSGGERKRLAFAVELLNNPVILFCDEPTTGLDSYSAQ 252
            .|::..:...||...:...||:. ..:.:||||:|||:.|:|:|..|.:||.||||:||||.||.
plant   127 DIVEATITDMGLEECSDRTIGNW-HLRGISGGEKKRLSIALEVLTKPSLLFLDEPTSGLDSASAF 190

  Fly   253 QLVATLYELAQKGTTILCTIHQPSSQLFDNFNNVMLLADGRVAFTGSPQHALSFFANHGYYCPEA 317
            .:|..|..:|..|.|::.:|||||.::|..|::::||:.|...:.|..:.|..||...|:.||..
plant   191 FVVQILRNIASSGKTVVSSIHQPSGEVFALFDDLLLLSGGETVYFGEAESATKFFGEAGFPCPSR 255

  Fly   318 YNPADFLIGVLATD-------------------------------------PGYEQASQRSAQHL 345
            .||:|..:..:.:|                                     |..|..:....:..
plant   256 RNPSDHFLRCVNSDFDNVTAALVESRRINDSSFSLHQLHETTNTLDPLDDIPTAEIRTTLVRKFK 320

  Fly   346 CDQFAVSSAAKQRDM--LVNLEIHMAQSGNFPFDTEVESFRGVAWYKRFHVVWLRASLTLLRDPT 408
            |..:|.:|.|:.:::  :|.:.            ||.:......|:|:..::..|:.:.:.||..
plant   321 CSLYAAASRARIQEIASIVGIV------------TERKKGSQTNWWKQLRILTQRSFINMSRDLG 373

  Fly   409 IQWLRFIQKIAMAFIIGACF--AGTTEPSQLGVQAVQGAL-----FIMISENTYHPMYSVLNLFP 466
            ..|:|....|.::..:|:.|  .|....:.:...|..|.:     |:.|..         ...|.
plant   374 YYWMRIAVYIVLSICVGSIFFNVGRNHTNVMSTAACGGFMAGFMTFMSIGG---------FQSFI 429

  Fly   467 QGFPLFMRETRSGLYSTGQYYAANILALLPGMIIEPL----IFVIICYWLTGLRSTFYAFGVTAM 527
            :...:|.||..:|.|....|..:|:|:.||.:|:..|    |.:.:..:.:|....||      .
plant   430 EEMKVFSRERLNGHYGVAVYTVSNLLSSLPFIILMCLSTSSITIYMVRFQSGGSHFFY------N 488

  Fly   528 CVVLVMNVATACGCFFSTAFNSVP-LAMAYLVPLDY--IFMITSGIFIQVNSLPVAFW-----WT 584
            |:.|:..:.|...|....| :.|| ..|..::...|  |.::::|.|.....||:.||     :.
plant   489 CLDLICAITTVESCMMMIA-SVVPNFLMGVMLGAGYIGIMVLSAGFFRFFPDLPMVFWRYPVSYI 552

  Fly   585 QFLSWML---YANE 595
            .:.:|.|   |.||
plant   553 NYGAWALQGAYKNE 566

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	ABCG_EPDR	66..298	CDD:213180	93/236 (39%)
		3a01204	67..665	CDD:273361	165/595 (28%)
		ABC2_membrane	395..600	CDD:279410	51/223 (23%)
ABCG13	NP_175557.1	3a01204	27..627	CDD:273361	157/574 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53689
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.780