DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment st and ABCG11

DIOPT Version :9

Sequence 1:	NP_524108.1	Gene:	st / 39836	FlyBaseID:	FBgn0003515	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_173226.2	Gene:	ABCG11 / 838363	AraportID:	AT1G17840	Length:	703	Species:	Arabidopsis thaliana

Alignment Length:	595	Identity:	173/595 - (29%)
Similarity:	287/595 - (48%)	Gaps:	81/595 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 PLRSYSKW---SPTE----QGATLVWRDLCVYTNVGGSGQRMKRIINNSTGAIQPGTLMALMGSS 110
            || |.:.|   :|||    ..|.|.|:||.|...:|..  ..:.::...||..:||:|.||||.|
plant    28 PL-SEAIWREKAPTEFVGDVSARLTWQDLTVMVTMGDG--ETQNVLEGLTGYAEPGSLTALMGPS 89

  Fly   111 GSGKTTLMSTLAFRQPAGTVVQGDILINGRRIGPFMHRISGYVYQDDLFLGSLTVLEHLNFMAHL 175
            ||||:|::..||.|..|...:.|.:|:|||:. ......:.||.|||..:|:|||.|.:.:.|.:
plant    90 GSGKSTMLDALASRLAANAFLSGTVLLNGRKT-KLSFGTAAYVTQDDNLIGTLTVRETIWYSARV 153

  Fly   176 RLDRRVSKEERRLIIKELLERTGLLSAAQTRIGSGDDKKVLSGGERKRLAFAVELLNNPVILFCD 240
            ||..::.:.|:|.:::..:...||...|.|.||:. ..:.:||||::|::.|:|:|..|.:||.|
plant   154 RLPDKMLRSEKRALVERTIIEMGLQDCADTVIGNW-HLRGISGGEKRRVSIALEILMRPRLLFLD 217

  Fly   241 EPTTGLDSYSAQQLVATLYELAQKGTTILCTIHQPSSQLFDNFNNVMLLADGRVAFTGSPQHALS 305
            |||:||||.||..:..||..|::.|.|::.:||||||::|:.|:.:.||:.|:..:.|....|..
plant   218 EPTSGLDSASAFFVTQTLRALSRDGRTVIASIHQPSSEVFELFDRLYLLSGGKTVYFGQASDAYE 282

  Fly   306 FFANHGYYCPEAYNPADFLIGVLATDPGYEQASQRSAQHLCDQFAVSSAAKQR---DMLVNLEIH 367
            |||..|:.||...||:|..:..:.:|....:|:.:.:..|  :|..|....::   ...:.|.:.
plant   283 FFAQAGFPCPALRNPSDHFLRCINSDFDKVRATLKGSMKL--RFEASDDPLEKITTAEAIRLLVD 345

  Fly   368 MAQSGNFPFDT-----EVESFRG---------VAWYKRFHVVWLRASLTLLRDPTIQWLRFIQKI 418
            ...:.::.:..     |:..|:|         .::..:.:.:..|:.:.:.||....|||.:..|
plant   346 YYHTSDYYYTAKAKVEEISQFKGTILDSGGSQASFLLQTYTLTKRSFINMSRDFGYYWLRLLIYI 410

  Fly   419 AMAFIIGACF--AGTTEPSQLGVQAVQGALFIMISENTYHPMYSVLNLFP---QGFPLFMRETRS 478
            .:...||..:  .||:..:.|...:....:|..::       :..:..||   :...:|.||..:
plant   411 LVTVCIGTIYLNVGTSYSAILARGSCASFVFGFVT-------FMSIGGFPSFVEDMKVFQRERLN 468

  Fly   479 GLYSTGQYYAANILALLPGMIIEPLIFVIICYWLTGLRS--TFYAFGVTAMCVVLVMNVATACGC 541
            |.|....:..||.|:..|.:|:...|...|||::.||..  |.|.|.|.               |
plant   469 GHYGVAAFVIANTLSATPFLIMITFISGTICYFMVGLHPGFTHYLFFVL---------------C 518

  Fly   542 FFS--TAFNSVPLAMAYLVP-----------LDYIFMITSGIFIQVNSLPVAFW-----WTQFLS 588
            .::  |...|:.:|:|.:||           :..|||:.||.|...|.:|..||     :..|..
plant   519 LYASVTVVESLMMAIASIVPNFLMGIIIGAGIQGIFMLVSGFFRLPNDIPKPFWRYPMSYISFHF 583

  Fly   589 WML---YANE 595
            |.|   |.|:
plant   584 WALQGQYQND 593

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	ABCG_EPDR	66..298	CDD:213180	89/231 (39%)
		3a01204	67..665	CDD:273361	166/574 (29%)
		ABC2_membrane	395..600	CDD:279410	57/229 (25%)
ABCG11	NP_173226.2	3a01204	66..601	CDD:273361	159/554 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53689
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.780