DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment st and ABCG41

DIOPT Version :9

Sequence 1:	NP_524108.1	Gene:	st / 39836	FlyBaseID:	FBgn0003515	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_001329357.1	Gene:	ABCG41 / 827186	AraportID:	AT4G15215	Length:	1397	Species:	Arabidopsis thaliana

Alignment Length:	648	Identity:	164/648 - (25%)
Similarity:	300/648 - (46%)	Gaps:	110/648 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 TPKLSKRNSSERSLPLRSYSKWSP------------TEQGAT----LVWRDLCV-YTNV------ 80
            |..|:.||:.:||..:.|:.|.|.            |.:..|    |.::.|.| :.||
plant   752 TLALTYRNNPQRSRAIVSHGKNSQCSEEDFKPCPEITSRAKTGKVILPFKPLTVTFQNVQYYIET 816

  Fly    81 --GGSGQRMKRIINNSTGAIQPGTLMALMGSSGSGKTTLMSTLAFRQPAGTVVQGDILING-RRI 142
              |    :.::::.:.|||::||.|.:|||.||:|||||:..|:.|:..| :::|:|.:.| .::
plant   817 PQG----KTRQLLFDITGALKPGVLTSLMGVSGAGKTTLLDVLSGRKTRG-IIKGEIRVGGYPKV 876

  Fly   143 GPFMHRISGYVYQDDLFLGSLTVLEHLNFMAHLRLDRRVSKEERRLIIKELLERTGLLSAAQTRI 207
            .....|:|||..|.|:...::||.|.|.:.|.|||...:..:.:..::||:||...|.....:.:
plant   877 QETFARVSGYCEQFDIHSPNITVEESLKYSAWLRLPYNIDAKTKNELVKEVLETVELEDIKDSMV 941

  Fly   208 G----SGDDKKVLSGGERKRLAFAVELLNNPVILFCDEPTTGLDSYSAQQLVATLYELAQKGTTI 268
            |    ||     ||..:||||..||||::||.|:|.||||||||:.:|..::..:..:|:.|.|:
plant   942 GLPGISG-----LSTEQRKRLTIAVELVSNPSIIFLDEPTTGLDARAAAIVMRAVKNVAETGRTV 1001

  Fly   269 LCTIHQPSSQLFDNFNNVMLLAD-GRVAFTGS-PQHA---LSFFANHGYYCP------EAYNPAD 322
            :|||||||..:|:.|:.::|:.| |::.:.|. .:|:   :.:|.:    .|      :..|||.
plant  1002 VCTIHQPSIDIFETFDELILMKDGGQLVYYGPLGKHSSKVIKYFES----IPGVPKVQKNCNPAT 1062

  Fly   323 FLIGVLATDPGYEQASQRSAQHLCDQFAVSSAAKQRDMLVNLEIHMAQSG----NFPFDTEVESF 383
            :::.:..     :.|..|........:..|:..|:..|:|. ::..|..|    :||     ..:
plant  1063 WMLDITC-----KSAEHRLGMDFAQAYKDSTLYKENKMVVE-QLSSASLGSEALSFP-----SRY 1116

  Fly   384 RGVAWYKRFHVVWLRASLTLLRDPTIQWLRFIQKIAMAFIIGACFAGTTEP--SQLGVQAVQGAL 446
            ....|.:....:| :...:..|:|:....|.:..:..:.:....|....:.  :|..:.::.|::
plant  1117 SQTGWGQLKACLW-KQHCSYWRNPSHNLTRIVFILLNSLLCSLLFWQKAKDINNQQDLFSIFGSM 1180

  Fly   447 FIMISENTYHPMYSVLNLFPQGFPLFMRETRSGLYSTGQYYAANILALLPGMIIEPLIFVIICYW 511
            :.::..:..:...:|:|.......:|.||..:.:||:..|..:.:|..:|..:::.|:..||.|.
plant  1181 YTIVIFSGINNCATVMNFIATERNVFYRERFARMYSSWAYSFSQVLVEVPYSLLQSLLCTIIVYP 1245

  Fly   512 LTGLRSTFYAFG---VTAMCVVLVMNVATACGCFFSTAFNSVPLAMAYLVPLDYIFMITSGIFIQ 573
            :.|...:.|...   .:..|.:|:.|.   ||           :.|..|.|..::.:.....|..
plant  1246 MIGYHMSVYKMFWSLYSIFCSLLIFNY---CG-----------MLMVALTPNIHMALTLRSTFFS 1296

  Fly   574 VNSLPVAF---------WWTQFLSWMLYAN------EAMTAAQWSGVQ-NITCFQESADLPCF 620
            :.:|...|         ||.    ||.|.:      |.:.::|:..|: .||.|.|...:..|
plant  1297 MVNLFAGFVMPKQKIPKWWI----WMYYLSPTSWVLEGLLSSQYGDVEKEITVFGEKKSVSAF 1355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	ABCG_EPDR	66..298	CDD:213180	89/250 (36%)
		3a01204	67..665	CDD:273361	154/608 (25%)
		ABC2_membrane	395..600	CDD:279410	40/224 (18%)
ABCG41	NP_001329357.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.870