DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment st and ABCG19

DIOPT Version :9

Sequence 1:	NP_524108.1	Gene:	st / 39836	FlyBaseID:	FBgn0003515	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_191073.1	Gene:	ABCG19 / 824679	AraportID:	AT3G55130	Length:	725	Species:	Arabidopsis thaliana

Alignment Length:	732	Identity:	184/732 - (25%)
Similarity:	326/732 - (44%)	Gaps:	127/732 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 APERVEQHELQVMPVGSTIEVPSLDSTPK----LSKRNSSERSLPLRS-------------YSKW 60
            |..||......:.|:||    |:||...|    ..|.:|.:   .::|             |.|.
plant    11 AMTRVSAETQYITPIGS----PTLDELLKDCDSFRKGDSGD---GVKSDDPAHHIIDVEALYVKP 68

  Fly    61 SPTEQGATLVWRDLCVYTNVGGSGQR-MKRIINNSTGAIQPGTLMALMGSSGSGKTTLMSTLAFR 124
            .|.......:..|:.:....|.|.|. :|.::::.:|....|.::|::|:||:||:||:..||.|
plant    69 VPYVLNFNNLQYDVTLRRRFGFSRQNGVKTLLDDVSGEASDGDILAVLGASGAGKSTLIDALAGR 133

  Fly   125 QPAGTVVQGDILINGRRI--GPFMHRISGYVYQDDLFLGSLTVLEHLNFMAHLRLDRRVSKEERR 187
            ...|: ::|.:.:||.::  ...:..||.||.||||....|||.|.|.|.:..||.|.:||.::.
plant   134 VAEGS-LRGSVTLNGEKVLQSRLLKVISAYVMQDDLLFPMLTVKETLMFASEFRLPRSLSKSKKM 197

  Fly   188 LIIKELLERTGLLSAAQTRIGSGDDKKVLSGGERKRLAFAVELLNNPVILFCDEPTTGLDSYSAQ 252
            ..::.|:::.||.:||.|.||. :..:.:|||||:|::..::::::|::||.||||:||||.:|.
plant   198 ERVEALIDQLGLRNAANTVIGD-EGHRGVSGGERRRVSIGIDIIHDPIVLFLDEPTSGLDSTNAF 261

  Fly   253 QLVATLYELAQKGTTILCTIHQPSSQLFDNFNNVMLLADGRVAFTGSPQHALSFFANHGYYCPEA 317
            .:|..|..:||.|:.::.:|||||:::.:..:.:::|:.|:..|.|||.....||::.|...||.
plant   262 MVVQVLKRIAQSGSIVIMSIHQPSARIVELLDRLIILSRGKSVFNGSPASLPGFFSDFGRPIPEK 326

  Fly   318 YNPADFLIGVLATDPGYEQASQRSAQHLCD--------QFAVSSAAKQRDML-----------VN 363
            .|.::|.:.::....|    |....:.|.|        :.::..:|.|.:.|           :|
plant   327 ENISEFALDLVRELEG----SNEGTKALVDFNEKWQQNKISLIQSAPQTNKLDQDRSLSLKEAIN 387

  Fly   364 LEIHMAQ-----SGNFPFDTE-VESFRGVAWYKRFHVVWLRASLTLLRDPTIQWLRFIQ----KI 418
            ..:...:     |.:.|...| |.|:...:.::.|         .|.:.....|:|..:    :|
plant   388 ASVSRGKLVSGSSRSNPTSMETVSSYANPSLFETF---------ILAKRYMKNWIRMPELVGTRI 443

  Fly   419 AMAFIIGACFAGTT----EPSQLGVQAVQGALFIMISENTYHPMYSVLNLFPQGFPLFMRETRSG 479
            |...:.| |...|.    :.:..|.|. :..||..:....::.....:.:|.|...:|:|||...
plant   444 ATVMVTG-CLLATVYWKLDHTPRGAQE-RLTLFAFVVPTMFYCCLDNVPVFIQERYIFLRETTHN 506

  Fly   480 LYSTGQYYAANILALLPGMIIEPLIFVIICYWLTGLRSTFYAFGVTAMCVVLVMNVATACGCFFS 544
            .|.|..|..::.|..||.::...|:|..|.:|..||......|....:.:.......::...|.|
plant   507 AYRTSSYVISHSLVSLPQLLAPSLVFSAITFWTVGLSGGLEGFVFYCLLIYASFWSGSSVVTFIS 571

  Fly   545 TAFNSVP-LAMAYLVPLDYI--FMITSGIFIQVNSLPVAFWWTQFLSWMLYANEAMTAAQWSGVQ 606
               ..|| :.:.|:|.:.|:  .::.||.::..:.:|..:.|..::|.:.|..||:...::
plant   572 ---GVVPNIMLCYMVSITYLAYCLLLSGFYVNRDRIPFYWTWFHYISILKYPYEAVLINEF---- 629

  Fly   607 NITCFQESADLP--CFHTGQDVLD-----------------------KYSFNESNVYR---NLLA 643
                     |.|  ||..|..|.|                       :....||...|   :|||
plant   630 ---------DDPSRCFVRGVQVFDSTLLGGVSDSGKVKLLETLSKSLRTKITESTCLRTGSDLLA 685

  Fly   644 MVGLYFGFHLLGYYCLW 660
            ..|:   ..|..:.|||
plant   686 QQGI---TQLSKWDCLW 699

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	ABCG_EPDR	66..298	CDD:213180	80/234 (34%)
		3a01204	67..665	CDD:273361	168/661 (25%)
		ABC2_membrane	395..600	CDD:279410	46/215 (21%)
ABCG19	NP_191073.1	P-loop_NTPase	89..307	CDD:304359	79/219 (36%)
		3a01204	90..724	CDD:273361	166/646 (26%)
		ABC2_membrane	424..627	CDD:279410	46/207 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.880