DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment st and ABCG18

DIOPT Version :9

Sequence 1:	NP_524108.1	Gene:	st / 39836	FlyBaseID:	FBgn0003515	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_191071.1	Gene:	ABCG18 / 824677	AraportID:	AT3G55110	Length:	708	Species:	Arabidopsis thaliana

Alignment Length:	735	Identity:	191/735 - (25%)
Similarity:	319/735 - (43%)	Gaps:	142/735 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SDSDSKRIDVE-APERVEQHELQVMPVGSTIEVPSLDSTPKLSKRNSSERSLPLRSYSKWSPTEQ 65
            :||..|:...| ||   .||.|.:.|...|..||.|.|...||      .::.||....:|..:.
plant    30 NDSGRKKYPGENAP---TQHILDLAPAAETRSVPFLLSFNNLS------YNVVLRRRFDFSRRKT 85

  Fly    66 GATLVWRDLCVYTNVGGSGQRMKRIINNSTGAIQPGTLMALMGSSGSGKTTLMSTLAFRQPAGTV 130
            .:                   :|.::::.||..:.|.::|::|.||:||:||:..||.| .|...
plant    86 AS-------------------VKTLLDDITGEARDGEILAVLGGSGAGKSTLIDALAGR-VAEDS 130

  Fly   131 VQGDILINGRRI--GPFMHRISGYVYQDDLFLGSLTVLEHLNFMAHLRLDRRVSKEERRLIIKEL 193
            ::|.:.:||.::  ...:..||.||.||||....|||.|.|.|.:..||.|.:.|.::...::.|
plant   131 LKGTVTLNGEKVLQSRLLKVISAYVMQDDLLFPMLTVKETLMFASEFRLPRSLPKSKKMERVETL 195

  Fly   194 LERTGLLSAAQTRIGSGDDKKVLSGGERKRLAFAVELLNNPVILFCDEPTTGLDSYSAQQLVATL 258
            :::.||.:||.|.||. :..:.:|||||:|::..::::::|::||.||||:||||.:|..:|..|
plant   196 IDQLGLRNAADTVIGD-EGHRGVSGGERRRVSIGIDIIHDPILLFLDEPTSGLDSTNAFMVVQVL 259

  Fly   259 YELAQKGTTILCTIHQPSSQLFDNFNNVMLLADGRVAFTGSPQHALSFFANHGYYCPEAYNPADF 323
            ..:||.|:.::.:|||||:::....:.:::|:.|:..|.|||....|||::.|...||..|..:|
plant   260 KRIAQSGSVVIMSIHQPSARIIGLLDRLIILSHGKSVFNGSPVSLPSFFSSFGRPIPEKENITEF 324

  Fly   324 LIGVLATDPG-----------YEQASQRSAQHLCDQFAVS-----SAAKQRDMLVNLEIHMAQSG 372
            .:.|:....|           .|:..|........|..||     :|:..|..||:     ..||
plant   325 ALDVIRELEGSSEGTRDLVEFNEKWQQNQTARATTQSRVSLKEAIAASVSRGKLVS-----GSSG 384

  Fly   373 NFPFDTE-VESFRG------VAWYKRFHVVWLRASLTLLRDPTIQWLRFIQKIAMAFIIGACFAG 430
            ..|...| |.|:..      ....||:...|:|.       |.:..:|    |....:.|...|.
plant   385 ANPISMETVSSYANPPLAETFILAKRYIKNWIRT-------PELIGMR----IGTVMVTGLLLAT 438

  Fly   431 T---TEPSQLGVQAVQG-------ALFIMISENTYHPMYSVLNLFPQGFPLFMRETRSGLYSTGQ 485
            .   .:.:..|.|...|       .:|...::|        :.:|.|...:|:|||....|.|..
plant   439 VYWRLDNTPRGAQERMGFFAFGMSTMFYCCADN--------IPVFIQERYIFLRETTHNAYRTSS 495

  Fly   486 YYAANILALLPGMIIEPLIFVIICYWLT----GLRSTFYAFGVTAMCVVLVMNVATACGCFFSTA 546
            |..::.|..||.::...:.|....:|..    ||.|.||      .|  |::..|...|....|.
plant   496 YVISHALVSLPQLLALSIAFAATTFWTVGLSGGLESFFY------YC--LIIYAAFWSGSSIVTF 552

  Fly   547 FNS-VP-LAMAYLVPLDYI--FMITSGIFIQVNSLPVAFWWTQFLSWMLYANEAMTAAQW----- 602
            .:. :| :.|:|:|.:.|:  .::..|.:|..:.:|:.:.|..::|.:.|..||:...::
plant   553 ISGLIPNVMMSYMVTIAYLSYCLLLGGFYINRDRIPLYWIWFHYISLLKYPYEAVLINEFDDPSR 617

  Fly   603 ---SGVQNI-------------------------TCFQESADLPCFHTGQDVLDKYSFNESNVYR 639
               .|||..                         |...||.   |..||.|:|.:....:.:.:.
plant   618 CFVKGVQVFDGTLLAEVSHVMKVKLLDTLSGSLGTKITEST---CLRTGPDLLMQQGITQLSKWD 679

  Fly   640 NLLAMVGLYFGFHLLGYYCL 659
            .|...:.....|.:|.|..|
plant   680 CLWITLAWGLFFRILFYLSL 699

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	ABCG_EPDR	66..298	CDD:213180	76/233 (33%)
		3a01204	67..665	CDD:273361	171/669 (26%)
		ABC2_membrane	395..600	CDD:279410	49/222 (22%)
ABCG18	NP_191071.1	3a01204	57..707	CDD:273361	180/705 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.880