DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment st and ABCG17

DIOPT Version :9

Sequence 1:	NP_524108.1	Gene:	st / 39836	FlyBaseID:	FBgn0003515	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_001319754.1	Gene:	ABCG17 / 824676	AraportID:	AT3G55100	Length:	662	Species:	Arabidopsis thaliana

Alignment Length:	640	Identity:	162/640 - (25%)
Similarity:	294/640 - (45%)	Gaps:	89/640 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 GGSGQRMKRIINNSTGAIQPGTLMALMGSSGSGKTTLMSTLAFRQPAGTVVQGDILINGRRIGPF 145
            |.|..::|.::|..||..:.|.::|::|:||:||:||:..||.:...|: ::|.:.:||..:...
plant    42 GHSPAKIKTLLNGITGEAKEGEILAILGASGAGKSTLIDALAGQIAEGS-LKGTVTLNGEALQSR 105

  Fly   146 MHR-ISGYVYQDDLFLGSLTVLEHLNFMAHLRLDRRVSKEERRLIIKELLERTGLLSAAQTRIGS 209
            :.| ||.||.|:||....|||.|.|.|.|..||.|.:||.::|..::.|:::.||.:...|.||.
plant   106 LLRVISAYVMQEDLLFPMLTVEETLMFAAEFRLPRSLSKSKKRNRVETLIDQLGLTTVKNTVIGD 170

  Fly   210 GDDKKVLSGGERKRLAFAVELLNNPVILFCDEPTTGLDSYSAQQLVATLYELAQKGTTILCTIHQ 274
             :..:.:|||||:|::...:::::|::||.||||:||||.||..:|..|.::|:.|:.::.:|||
plant   171 -EGHRGVSGGERRRVSIGTDIIHDPIVLFLDEPTSGLDSTSAFMVVQVLKKIARSGSIVIMSIHQ 234

  Fly   275 PSSQLFDNFNNVMLLADGRVAFTGSPQHALSFFANHGYYCPEAYNPADFLIGVLATDPGYEQASQ 339
            ||.::.:..:.|::|:.|::.|:.||.....||:..|...||..|.|:|.:.::....|..:.::
plant   235 PSGRIMEFLDRVIVLSSGQIVFSDSPATLPLFFSEFGSPIPEKENIAEFTLDLIKDLEGSPEGTR 299

  Fly   340 ------RSAQHLCDQFAVSSAAKQRDMLVNLEIHMAQSG-NFPFDTEVE-------SFRGVAWY- 389
                  |:.||             |.:.|:.|.|...|. ....:..:.       |:|.:..|
plant   300 GLVEFNRNWQH-------------RKLRVSQEPHHNSSSLGEAINASISRGKLVSTSYRSIPSYV 351

  Fly   390 -----------KRFHVVWLRASLTLLRDPTIQWLRFIQKIAMAFIIGACFAGTTEPSQLGVQAVQ 443
                       ||:.:.|.|.       |.:...|....:...|::...: ...:.|..|||. :
plant   352 NPWWVETVILAKRYMINWTRT-------PELIGTRVFIVMMTGFLLATVY-WKVDDSPRGVQE-R 407

  Fly   444 GALFIMISENTYHPMYSVLNLFPQGFPLFMRETRSGLYSTGQYYAANILALLPGMIIEPLIFVII 508
            .:.|.......::.....|..|.|...:|:|||....|....|..::.|..||.:....:.|...
plant   408 LSFFSFAMATMFYSCADGLPAFIQERYIFLRETAHNAYRRSSYVISHSLVTLPHLFALSIGFAAT 472

  Fly   509 CYWLTGLRSTFYAFGVTAMCVVLVMNVATACGCFFSTAFNSV--PLAMAYLVPLDYI--FMITSG 569
            .:|..||......|    :..::::..:...||.|.|..:.|  .:.|:|:|...|:  .::.||
plant   473 TFWFVGLNGGLAGF----IYYLMIIFASFWSGCSFVTFVSGVIPNVMMSYMVTFGYLSYCLLFSG 533

  Fly   570 IFIQVNSLPVAFWWTQFLSWMLYANEAMTAAQW-------------------SGVQNIT------ 609
            .::..:.:.:.:.|..::|.:.|..||:...::                   .||...|
plant   534 FYVNRDRIHLYWIWIHYISLLKYPYEAVLHNEFDDPSRCFVRGNQVFDNTIMEGVSETTKAKLLE 598

  Fly   610 -----CFQESADLPCFHTGQDVLDKYSFNESNVYRNLLAMVGLYFGFHLLGYYCL 659
                 ...|..:..|..||.|:|.::...:.:.:..|...:...|.|.:|.|:.|
plant   599 TMSGYLGMELTESTCLTTGSDLLKQHGIEQLDKWGCLWVTLAWGFFFRILFYFSL 653

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	ABCG_EPDR	66..298	CDD:213180	80/217 (37%)
		3a01204	67..665	CDD:273361	162/640 (25%)
		ABC2_membrane	395..600	CDD:279410	43/208 (21%)
ABCG17	NP_001319754.1	3a01204	18..661	CDD:273361	162/640 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.880