DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment st and ABCG16

DIOPT Version :9

Sequence 1:	NP_524108.1	Gene:	st / 39836	FlyBaseID:	FBgn0003515	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_191069.2	Gene:	ABCG16 / 824675	AraportID:	AT3G55090	Length:	736	Species:	Arabidopsis thaliana

Alignment Length:	733	Identity:	199/733 - (27%)
Similarity:	321/733 - (43%)	Gaps:	116/733 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SDSKRIDV--EAPERVEQHELQVMPVGSTIE---------VPSLDSTPKLSKRNSSERSLPLRSY 57
            ||.::::|  |.|    .||..... ||:::         ||.:.|...|:...|..|.|.....
plant    34 SDVRKVEVGDETP----VHEFFDRD-GSSLDGDNDHLMRPVPFVLSFNNLTYNVSVRRKLDFHDL 93

  Fly    58 SKWSPTEQGATLVWRDLCVYTNVGGSGQRMKRIINNSTGAIQPGTLMALMGSSGSGKTTLMSTLA 122
            ..|..|                   |..:.|.:::|.:|..:.|.::|::|:|||||:||:..||
plant    94 VPWRRT-------------------SFSKTKTLLDNISGETRDGEILAVLGASGSGKSTLIDALA 139

  Fly   123 FRQPAGTVVQGDILINGRRIGPFMHR-ISGYVYQDDLFLGSLTVLEHLNFMAHLRLDRRVSKEER 186
            .|...|: ::|.:.:||..:...|.: ||.||.||||....|||.|.|.|.|..||.|.:.|.::
plant   140 NRIAKGS-LKGTVTLNGEALQSRMLKVISAYVMQDDLLFPMLTVEETLMFAAEFRLPRSLPKSKK 203

  Fly   187 RLIIKELLERTGLLSAAQTRIGSGDDKKVLSGGERKRLAFAVELLNNPVILFCDEPTTGLDSYSA 251
            :|.::.|:::.|:.:||:|.||. :..:.:|||||:|::..::::::|::||.||||:||||.||
plant   204 KLRVQALIDQLGIRNAAKTIIGD-EGHRGISGGERRRVSIGIDIIHDPIVLFLDEPTSGLDSTSA 267

  Fly   252 QQLVATLYELAQKGTTILCTIHQPSSQLFDNFNNVMLLADGRVAFTGSPQHALSFFANHGYYCPE 316
            ..:|..|..:|:.|:.|:.:|||||.::....:.::.|:.|...|:|||....||||..|...||
plant   268 FMVVKVLKRIAESGSIIIMSIHQPSHRVLSLLDRLIFLSRGHTVFSGSPASLPSFFAGFGNPIPE 332

  Fly   317 AYNPADFLIGVLATDPG---------------YEQASQRSAQHLCDQFAVS---------SAAKQ 357
            ..|..:|.:.::....|               .|...|.:.|.|....:.:         ||:..
plant   333 NENQTEFALDLIRELEGSAGGTRGLVEFNKKWQEMKKQSNPQTLTPPASPNPNLTLKEAISASIS 397

  Fly   358 RDMLVNLEIHMAQSG--------NFPFDT-EVESFRGVAWYKRFHVVWLRASLTLLRDPTIQWLR 413
            |..||        ||        |....| .|.:|....|.: ...:..|:.|...|.|.:..:|
plant   398 RGKLV--------SGGGGGSSVINHGGGTLAVPAFANPFWIE-IKTLTRRSILNSRRQPELLGMR 453

  Fly   414 FIQKIAMAFIIGACFAGTTEPSQLGVQAVQGALFIMISENTYHPMYSVLNLFPQGFPLFMRETRS 478
            ....|...||:...| ...:.|..|||...| .|.......::.....|.:|.|...:|||||..
plant   454 LATVIVTGFILATVF-WRLDNSPKGVQERLG-FFAFAMSTMFYTCADALPVFLQERYIFMRETAY 516

  Fly   479 GLYSTGQYYAANILALLPGMIIEPLIFVIICYWLTGLRSTFYAFGVTAMCVVLVMNV--ATACGC 541
            ..|....|..::.:...|.:|...|.|.:..:|..||....  .|....|::::.:.  .::...
plant   517 NAYRRSSYVLSHAIVTFPSLIFLSLAFAVTTFWAVGLEGGL--MGFLFYCLIILASFWSGSSFVT 579

  Fly   542 FFSTAFNSVPLAMAYLVPLDYIFMITSGIFIQVNSLPVAFWWTQFLSWMLYANEAMTAAQWSG-- 604
            |.|.....|.|....:|.:...|::.||.||..:.:|..:.|..:||.:.|..||:...::|.
plant   580 FLSGVVPHVMLGYTIVVAILAYFLLFSGFFINRDRIPQYWIWFHYLSLVKYPYEAVLQNEFSDPT 644

  Fly   605 ---VQNITCFQES-------------------------ADLPCFHTGQDVLDKYSFNESNVYRNL 641
               |:.:..|..|                         :...|..||.|||.:....:.:.:..|
plant   645 ECFVRGVQLFDNSPLGELTYGMKLRLLDSVSRSIGMRISSSTCLTTGADVLKQQGVTQLSKWNCL 709

  Fly   642 LAMVGLYFGFHLLGYYCL 659
            |..||..|.|.:|.|.||
plant   710 LITVGFGFLFRILFYLCL 727

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	ABCG_EPDR	66..298	CDD:213180	81/232 (35%)
		3a01204	67..665	CDD:273361	181/659 (27%)
		ABC2_membrane	395..600	CDD:279410	51/206 (25%)
ABCG16	NP_191069.2	3a01204	75..735	CDD:273361	187/687 (27%)
		P-loop_NTPase	85..314	CDD:304359	85/249 (34%)
		ABC2_membrane	435..638	CDD:279410	51/206 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.880