DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment st and ABCA8

DIOPT Version :9

Sequence 1:	NP_524108.1	Gene:	st / 39836	FlyBaseID:	FBgn0003515	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_190363.3	Gene:	ABCA8 / 823933	AraportID:	AT3G47790	Length:	901	Species:	Arabidopsis thaliana

Alignment Length:	311	Identity:	83/311 - (26%)
Similarity:	141/311 - (45%)	Gaps:	39/311 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VEAPERVEQH--ELQVMPVGSTIEVPSLDSTPKLSKRNSSERSLPLRSYSKWSPTEQGATLVWRD 73
            :::..:.:||  :.::..|...:|.|.:     ..:|...|:.| |:|      |...|.|....
plant   539 LQSTSKKKQHFSDNKISKVVVEMEKPDV-----CREREKVEQCL-LKS------TRDSAVLCNNL 591

  Fly    74 LCVYTNVGGSGQRMKRIINNSTGAIQPGTLMALMGSSGSGKTTL--MSTLAFRQPAGTV-VQG-D 134
            ..||:  |..|...|..:...:.|:..|....::|.:|:|||:.  |.|...:..:||. ||| |
plant   592 KKVYS--GKDGNPQKLAVRGLSLALPQGECFGMLGPNGAGKTSFINMMTGIIKPSSGTAFVQGLD 654

  Fly   135 ILINGRRIGPFMHRISGYVYQDDLFLGSLTVLEHLNFMAHLRLDRRVSKEERRLIIKELLERTGL 199
            ||.:..||    :...|...|.||....|:..|||.|...|       |..:..::.:.:|.:
plant   655 ILTDMDRI----YTTIGVCPQHDLLWEKLSGREHLLFYGRL-------KNLKGSVLTQAVEES-- 706

  Fly   200 LSAAQTRIGSGDDKKV--LSGGERKRLAFAVELLNNPVILFCDEPTTGLDSYSAQQLVATLYELA 262
            |.:.....|...||:|  .|||.::||:.|:.|:.:|.:::.|||:||||..|.:.|...:....
plant   707 LRSVNLFHGGIGDKQVSKYSGGMKRRLSVAISLIGSPKVVYMDEPSTGLDPASRKSLWDVVKRAK 771

  Fly   263 QKGTTILCTIHQPSSQLFDNFNNVMLLADGRVAFTGSPQHALSFFANHGYY 313
            :||..||.|.....:::.  .:.:.:..||.:...|:|:...|.:.  |.|
plant   772 RKGAIILTTHSMEEAEIL--CDRIGIFVDGSLQCIGNPKELKSRYG--GSY 818

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	ABCG_EPDR	66..298	CDD:213180	67/237 (28%)
		3a01204	67..665	CDD:273361	72/253 (28%)
		ABC2_membrane	395..600	CDD:279410
ABCA8	NP_190363.3	ABC2_membrane_3	<247..488	CDD:289468
		BI-1-like	367..>451	CDD:294323
		CcmA	585..897	CDD:224054	72/253 (28%)
		ABC_subfamily_A	590..811	CDD:213230	67/237 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910