DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment st and NAP12

DIOPT Version :9

Sequence 1:	NP_524108.1	Gene:	st / 39836	FlyBaseID:	FBgn0003515	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_001323430.1	Gene:	NAP12 / 818275	AraportID:	AT2G37010	Length:	1082	Species:	Arabidopsis thaliana

Alignment Length:	618	Identity:	171/618 - (27%)
Similarity:	282/618 - (45%)	Gaps:	85/618 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 KRIINNSTGAIQPGTLMALMGSSGSGKTTLMSTLAFRQPAGTVVQGDILINGRR--IGPFMHRIS 150
            |.|:.:.||.|.||.:.|:||.||:||||.:|.|| .:..|....|.||||||.  |..: .:|:
plant   498 KHILRSVTGKIMPGRVSAVMGPSGAGKTTFLSALA-GKATGCTRTGLILINGRNDSINSY-KKIT 560

  Fly   151 GYVYQDDLFLGSLTVLEHLNFMAHLRLDRRVSKEERRLIIKELLERTGLLSAAQTRIGSGDDKKV 215
            |:|.|||:..|:|||.|:|.|.|..||...:||.::.|||:.::|..||.....:.:|: .:|:.
plant   561 GFVPQDDVVHGNLTVEENLRFSARCRLSAYMSKADKVLIIERVIESLGLQHVRDSLVGT-IEKRG 624

  Fly   216 LSGGERKRLAFAVELLNNPVILFCDEPTTGLDSYSAQQLVATLYELAQKGTTILCTIHQPSSQLF 280
            :|||:|||:...||::..|.:|..|||||||||.|:|.|:..|...|.:|..|...:||||..::
plant   625 ISGGQRKRVNVGVEMVMEPSLLILDEPTTGLDSASSQLLLRALRREALEGVNICMVVHQPSYTMY 689

  Fly   281 DNFNNVMLLADGRV-AFTGSPQHALSFFANHGYYCPEAYNPADFLIGVLA------TDPGYEQAS 338
            ..|:::::||.|.: .:.||.:....:||:.|...|:..||.|..|.:|.      .|...||..
plant   690 KMFDDMIILAKGGLTVYHGSVKKIEEYFADIGITVPDRVNPPDHYIDILEGIVKPDGDITIEQLP 754

  Fly   339 QRSAQH-----------LCDQFAVSSAAKQ--------------RDMLVNLEIHMAQSGNFPFDT 378
            .|...|           .||....||....              :|:..|:||...|..:...::
plant   755 VRWMLHNGYPVPHDMLKFCDGLPSSSTGSAQEDSTHNSFSNDLWQDVKTNVEITKDQLQHNYSNS 819

  Fly   379 EVESFRGVAWYKRFHVVWL-RASLTLLRDPTIQWLRFIQKIAMAFIIGACFAGTTEPSQLGVQAV 442
            ...|.|......|.:..:: |.....||:..:|.|.|:    :..:.|||.....:.:...:..:
plant   820 HDNSNRVTPTVGRQYRYFVGRVGKQRLREARLQALDFL----ILLVAGACLGTLAKVNDETIDTL 880

  Fly   443 QGALFIMISENTYHPMYSVLNLFPQGFPLFMRETRSGLYSTGQYYAANILALLPGMIIEPLIFVI 507
             |..:.:|:.:....: |.|..|......:.||:.:|:.|...:.|.:.:..| ..|::||:::.
plant   881 -GYTYTIIAVSLLCKI-SALRSFSVDKLQYWRESAAGISSLAHFMAKDTMDHL-NTIMKPLVYLS 942

  Fly   508 ICYWLTGLRSTFYAFGVTAMCVVLVMNVATACGCFFSTAFNS---------VPLAMAYLVPLDYI 563
            :.|:....||:|....:..:|:|..:   |.....|:..::.         ||:.|..:...|..
plant   943 MFYFFNNPRSSFEDNYIVLVCLVYCV---TGMAYIFAILYSPSAAQLLSVLVPVVMTLIANQDKE 1004

  Fly   564 FMITS--GIFIQVNSLPVAFWWTQFLSWMLYANEAMTAAQWSGVQNITCFQESADLPCFHTGQDV 626
            .|:..  |.|.             :..|.|.|.....|.::|||..:|        .|....|
plant  1005 SMVLKYLGSFC-------------YPKWTLEAFVLSNAQRYSGVWVVT--------RCSSLSQ-- 1046

  Fly   627 LDKYSFNESNVYRNLLAMVGLYFGFHLLGYYCL 659
             :.|..::..:...:|.::||...|  :.|:|:
plant  1047 -NGYDLSDWILCLIVLVLMGLICRF--IAYFCM 1076

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	ABCG_EPDR	66..298	CDD:213180	88/212 (42%)
		3a01204	67..665	CDD:273361	171/618 (28%)
		ABC2_membrane	395..600	CDD:279410	41/216 (19%)
NAP12	NP_001323430.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.780