DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment st and ABCG7

DIOPT Version :9

Sequence 1:	NP_524108.1	Gene:	st / 39836	FlyBaseID:	FBgn0003515	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_849922.1	Gene:	ABCG7 / 814660	AraportID:	AT2G01320	Length:	728	Species:	Arabidopsis thaliana

Alignment Length:	632	Identity:	186/632 - (29%)
Similarity:	319/632 - (50%)	Gaps:	50/632 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 WSPTEQG-------ATLVWRDL-CVYTNVGGSGQRMKRIINNSTGAIQPGTLMALMGSSGSGKTT 116
            ::.||.|       .|:.||:: |..::  .|.:.::.::.|.:|..:||.|:|:||.|||||||
plant    54 YAETEDGGGDSIRPVTIRWRNITCSLSD--KSSKSVRFLLKNVSGEAKPGRLLAIMGPSGSGKTT 116

  Fly   117 LMSTLAFRQPAGTV-------VQGDILINGRRIGPFMHRISGYVYQDDLFLGSLTVLEHLNFMAH 174
            |::.|     ||.:       :.|.:.:||:......:::: :|.|:|||...|||.|.|:|.|.
plant   117 LLNVL-----AGQLSLSPRLHLSGLLEVNGKPSSSKAYKLA-FVRQEDLFFSQLTVRETLSFAAE 175

  Fly   175 LRLDRRVSKEERRLIIKELLERTGLLSAAQTRIGSGDDKKV--LSGGERKRLAFAVELLNNPVIL 237
            |:|....|.|||...:..||.:.||:|.|.:.:|   |.||  :||||:|||:.|.||:.:|.::
plant   176 LQLPEISSAEERDEYVNNLLLKLGLVSCADSCVG---DAKVRGISGGEKKRLSLACELIASPSVI 237

  Fly   238 FCDEPTTGLDSYSAQQLVATLYELAQKGTTILCTIHQPSSQLFDNFNNVMLLADGRVAFTG-SPQ 301
            |.||||||||::.|::::.||.:|||.|.|::|:||||...::..|::::||.:|.:.:.| :.:
plant   238 FADEPTTGLDAFQAEKVMETLQKLAQDGHTVICSIHQPRGSVYAKFDDIVLLTEGTLVYAGPAGK 302

  Fly   302 HALSFFANHGYYCPEAYNPADFLIGVLATDPGYEQ---ASQRSAQHLCDQFAVSSAAKQRDMLVN 363
            ..|::|.|.|:.|||..|||:||..:::.|....:   :||:....|.|.|:..|::    :|..
plant   303 EPLTYFGNFGFLCPEHVNPAEFLADLISVDYSSSETVYSSQKRVHALVDAFSQRSSS----VLYA 363

  Fly   364 LEIHM---AQSGNFPFDTEVESFRGVAWYKRFHVVWLRASLTLLRDPTIQWLRFIQKIAMAFIIG 425
            ..:.|   .::|..|....:.. |...|:::|.::..||.:...||.....:|....:|.|.|.|
plant   364 TPLSMKEETKNGMRPRRKAIVE-RTDGWWRQFFLLLKRAWMQASRDGPTNKVRARMSVASAVIFG 427

  Fly   426 ACFAGTTEPSQLGVQAVQGALFIMISENTYHPMYSVLNLFPQGFPLFMRETRSGLYSTGQYYAAN 490
            :.| .....||..:|...|.|.:.........:...:.:||:...:..||...|.||.|.|..:.
plant   428 SVF-WRMGKSQTSIQDRMGLLQVAAINTAMAALTKTVGVFPKERAIVDRERSKGSYSLGPYLLSK 491

  Fly   491 ILALLPGMIIEPLIFVIICYWLTGLRSTFYAFGVTAMCVVLVMNVATACGCFFSTAFNSVPLAMA 555
            .:|.:|.....||:|..:.|.:..|..|...||.....|.:....|:|.|........|...|||
plant   492 TIAEIPIGAAFPLMFGAVLYPMARLNPTLSRFGKFCGIVTVESFAASAMGLTVGAMVPSTEAAMA 556

  Fly   556 YLVPLDYIFMITSGIFIQVNSLPVAFWWTQFLSWMLYANEAMTAAQWSGVQNITCF--QESADLP 618
            ....|..:|::..|.::..::.|:.|.|....|.:.:|.:.:...::||::    |  |.:.|:
plant   557 VGPSLMTVFIVFGGYYVNADNTPIIFRWIPRASLIRWAFQGLCINEFSGLK----FDHQNTFDV- 616

  Fly   619 CFHTGQDVLDKYSFNESNVYRNLLAMVGLYFGFHLLGYYCLWRRARK 665
              .||:..|::.||....:...:.|...:...::...|..|.:...|
plant   617 --QTGEQALERLSFGGRRIRETIAAQSRILMFWYSATYLLLEKNKPK 661

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	ABCG_EPDR	66..298	CDD:213180	93/248 (38%)
		3a01204	67..665	CDD:273361	182/616 (30%)
		ABC2_membrane	395..600	CDD:279410	50/204 (25%)
ABCG7	NP_849922.1	ABCG_EPDR	67..298	CDD:213180	92/241 (38%)
		3a01204	90..655	CDD:273361	176/586 (30%)
		ABC2_membrane	397..601	CDD:279410	50/204 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	116	1.000	Domainoid score	I1972
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	304	1.000	Inparanoid score	I769
OMA	1	1.010	-	-		QHG53689
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	1	1.000	-	-		mtm1120
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.840