Protein Alignment st and Abcg8

DIOPT Version :9

• Sequence 1: NP_524108.1
• Gene: st / 39836
• FlyBaseID: FBgn0003515
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_080456.1
• Gene: Abcg8 / 67470
• MGIID: 1914720
• Length: 673
• Species: Mus musculus
• Alignment Length: 689
• Identity: 178/689 - (25%)
• Similarity: 297/689 - (43%)
• Gaps: 130/689 - (18%)

  Fly    29 STIEVPSLDSTPKLSKR-----NSSERSLPLRSYSKWSPTEQGATLVWRDLCVYTNVGGSGQRMK 88
            :|:||..|.....::.:     ..::..:|.||:|.....|.|
Mouse    46 NTLEVRDLTYQVDIASQVPWFEQLAQFKIPWRSHSSQDSCELG---------------------- 88

  Fly    89 RIINNSTGAIQPGTLMALMGSSGSGKTTLMSTLAFRQPAGTVVQGDILINGRRIGP-FMHRISGY 152
              |.|.:..::.|.::|::||||.|:.:|:..:..|...|.:..|.|.|||:...| .:.:...:
Mouse    89 --IRNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGHGGKMKSGQIWINGQPSTPQLVRKCVAH 151

  Fly   153 VYQDDLFLGSLTVLEHLNFMAHLRLDRRVSKEERRLIIKELLERTGLLSAAQTRIGSGDDKKVLS 217
            |.|.|..|.:|||.|.|.|:|.:||.|..|:.:|...:::::....|...|.||:|:...:.| |
Mouse   152 VRQHDQLLPNLTVRETLAFIAQMRLPRTFSQAQRDKRVEDVIAELRLRQCANTRVGNTYVRGV-S 215

  Fly   218 GGERKRLAFAVELLNNPVILFCDEPTTGLDSYSAQQLVATLYELAQKGTTILCTIHQPSSQLFDN 282
            ||||:|::..|:||.||.||..||||:||||::|..||.||..||:....:|.::|||.|.:|..
Mouse   216 GGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVTTLSRLAKGNRLVLISLHQPRSDIFRL 280

  Fly   283 FNNVMLLADGRVAFTGSPQHALSFFANHGYYCPEAYNPADFLIGVLATDPGYEQASQRSAQHLCD 347
            |:.|:|:..|...:.|:.|..:.:|.:.|:.||...|||||.:.:.:.|       :||
Mouse   281 FDLVLLMTSGTPIYLGAAQQMVQYFTSIGHPCPRYSNPADFYVDLTSID-------RRS------ 332

  Fly   348 QFAVSSAAKQRDMLVNLEIHMAQSGNFPFDTEVESFRGVAW---YKRFHVVWLRASLTLLRD--- 406
                    |:|::..   :..|||....|..:|:.|....|   .|..:......||||.:|
Mouse   333 --------KEREVAT---VEKAQSLAALFLEKVQGFDDFLWKAEAKELNTSTHTVSLTLTQDTDC 386

  Fly   407 ----------------------------PTIQWLRFIQKIAMAFIIGACFAGTTEPSQLGVQAVQ 443
                                        ||: .:...:...|:.|||..:.| ....||......
Mouse   387 GTAVELPGMIEQFSTLIRRQISNDFRDLPTL-LIHGSEACLMSLIIGFLYYG-HGAKQLSFMDTA 449

  Fly   444 GALFIMISENTYHPMYSVLNLFPQGFPLFMRETRSGLYSTGQYYAANILALLPGMIIEPLIFVII 508
            ..||::.:...::.:..|::.......:...|...|||:.|.|:.|.||..||......:|:.:.
Mouse   450 ALLFMIGALIPFNVILDVVSKCHSERSMLYYELEDGLYTAGPYFFAKILGELPEHCAYVIIYAMP 514

  Fly   509 CYWLTGLRSTFYAFGVTAMCVVLVMNVATACGCFFSTAFNSVPLAMAYLVPLDYI---------- 563
            .||||.||.....|   .:..:||..|...|        .::.||.:.::|..::
Mouse   515 IYWLTNLRPVPELF---LLHFLLVWLVVFCC--------RTMALAASAMLPTFHMSSFFCNALYN 568

  Fly   564 -FMITSGIFIQVNSLPVAFWWTQFLSWMLYANEAMTAAQWSG------VQNITCFQESADLPCFH 621
             |.:|:|..|.:::|.:...|...||::.:....:...|::|      :.|.|          |.
Mouse   569 SFYLTAGFMINLDNLWIVPAWISKLSFLRWCFSGLMQIQFNGHLYTTQIGNFT----------FS 623

  Fly   622 -TGQDVLDKYSFNESNVYRNLLAMVGLYFGFHLLGYYCL 659
             .|..::.....|...:|...|.::|:.:||..|.|..|
Mouse   624 ILGDTMISAMDLNSHPLYAIYLIVIGISYGFLFLYYLSL 662

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	ABCG_EPDR	66..298	CDD:213180	79/232 (34%)
		3a01204	67..665	CDD:273361	168/646 (26%)
		ABC2_membrane	395..600	CDD:279410	51/246 (21%)
Abcg8	NP_080456.1	ABCG_White	71..296	CDD:213201	84/249 (34%)
		3a01204	89..664	CDD:273361	168/622 (27%)
		ABC2_membrane	402..606	CDD:279410	46/216 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831364
Domainoid	1	1.000	90	1.000	Domainoid score	I7740
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53689
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.760