Protein Alignment st and abcg4a

DIOPT Version :9

• Sequence 1: NP_524108.1
• Gene: st / 39836
• FlyBaseID: FBgn0003515
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: XP_687685.2
• Gene: abcg4a / 564842
• ZFINID: ZDB-GENE-050517-39
• Length: 641
• Species: Danio rerio
• Alignment Length: 645
• Identity: 183/645 - (28%)
• Similarity: 310/645 - (48%)
• Gaps: 95/645 - (14%)

  Fly    52 LPLRSYSKWSPTEQGATL----VWRDLCVYTNVGGSGQRMKRIINNSTGAIQPGTLMALMGSSGS 112
            ||.||......||...|:    .||           .:..|.::...:|......|:.:||.||:
Zfish    47 LPRRSTVDLEFTELSYTIREGPCWR-----------RRGFKALLKCLSGKFCSRELIGIMGPSGA 100

  Fly   113 GKTTLMSTLA-FRQPAGTVVQGDILINGR-RIGPFMHRISGYVYQDDLFLGSLTVLEHLNFMAHL 175
            ||:|||:.|| :|:   |.::|.||:||| |......::|.|:.|||:.|..||..|.:...|:|
Zfish   101 GKSTLMNILAGYRE---TGMKGQILVNGRPRDLRTFRKMSCYIMQDDMLLPHLTTREAMMVSANL 162

  Fly   176 RLDRRVSKEERRLIIKELLERTGLLSAAQTRIGSGDDKKVLSGGERKRLAFAVELLNNPVILFCD 240
            :|:..:  |.::.::.|:|...||...||||..|      ||||:.||||.|:||:|||.::|.|
Zfish   163 KLNENM--EVKKELVNEILTALGLQECAQTRTIS------LSGGQCKRLAIALELVNNPPVMFFD 219

  Fly   241 EPTTGLDSYSAQQLVATLYELAQKGTTILCTIHQPSSQLFDNFNNVMLLADGRVAFTGSPQHALS 305
            |||:||||.|..|:|:.:..|||.|.||:|||||||::||:.|:.:.:|:.|:..:.|:..:.:.
Zfish   220 EPTSGLDSASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIYKGTVPYLIP 284

  Fly   306 FFANHGYYCPEAYNPADFLIGVLA-----TDPGYEQASQRSAQHLCDQFAVSSAAKQRDMLVNLE 365
            :..|.|.:||..:|||||:|.|.:     .:|...:|.|..   ||...:..:::.:.|...:
Zfish   285 YLKNLGLHCPTYHNPADFIIEVASGEYGDLNPVLFEAVQGG---LCSDDSKKNSSDKNDPTTS-- 344

  Fly   366 IHMAQSGNFPFDTEVESFR-GVAWYKRFHVVWLRASLTLLRDPTIQWLRFIQKIAMAFIIGACFA 429
               ..|..:|....:|... ..:...:|.:::.|..:|:.||..:..||.:..:.:..:||..:.
Zfish   345 ---CPSQCYPDSGYIEKHTFATSTLTQFCILFKRTFITICRDVVLTHLRVMSHLCIGVLIGLLYL 406

  Fly   430 GTTEPSQLGVQAVQGALFIMISENTYHPMYSVLNL-----------FPQGFPLFMRETRSGLYST 483
                  .:|..|.:      :..||....:|:|.|           ||....:|:||..:..||.
Zfish   407 ------NIGNDASK------VFNNTGFLFFSMLFLMFAALMPTVLTFPLEMGVFIREHLNYWYSL 459

  Fly   484 GQYYAANILALLPGMIIEPLIFVIICYWLT------GLRSTFYAFGV-TAMCVVLVMNVATACGC 541
            ..||.|..:|.:|..:|.|:::..|.||:|      |....|.|... ||:       ||.:.|.
Zfish   460 KAYYLAKTMADIPFQVICPIMYCSIVYWMTEQPPEAGRYLLFMALSTSTAL-------VAQSLGL 517

  Fly   542 FFSTAFNSVPLAMAYLVPLDYI-FMITSGIFIQVNSLPVAFWWTQFLSWMLYANEAMTAAQWSGV 605
            ....|..|:.:| .::.|:..| .::.||.|:..:::|....|:.::|::.|..|.:..:.:.
Zfish   518 LIGAASTSLQVA-TFVGPVSAIPVLLFSGFFVNFDTIPKYLQWSSYVSYVRYGFEGVILSIYG-- 579

  Fly   606 QNITCFQESADLPC------FHTGQDVLDKYSFNESNVYRNLLAMVGLYFGFHLLGYYCL 659
                  ...::|.|      |...::||......::.:|.:.:.:...:....|..|:.|
Zfish   580 ------MNRSELECPGIVCKFQKPEEVLQLLDVEDAKLYVDFMVLGVFFLVLRLATYFVL 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	ABCG_EPDR	66..298	CDD:213180	92/237 (39%)
		3a01204	67..665	CDD:273361	177/630 (28%)
		ABC2_membrane	395..600	CDD:279410	54/223 (24%)
abcg4a	XP_687685.2	3a01204	38..641	CDD:273361	183/645 (28%)
		ABCG_EPDR	53..277	CDD:213180	94/245 (38%)
		ABC2_membrane	372..574	CDD:279410	54/221 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574370
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.840