Protein Alignment st and abcg1

DIOPT Version :9

• Sequence 1: NP_524108.1
• Gene: st / 39836
• FlyBaseID: FBgn0003515
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_001103924.1
• Gene: abcg1 / 556979
• ZFINID: ZDB-GENE-070424-84
• Length: 673
• Species: Danio rerio
• Alignment Length: 683
• Identity: 196/683 - (28%)
• Similarity: 336/683 - (49%)
• Gaps: 77/683 - (11%)

  Fly     5 DSKRIDVEAPERVEQHELQVMPVGSTIEVPSLDSTPKLSKRNSSERSLPLRSYSKWSPTEQGATL 69
            |.:.:.|...|.:..|.       |:.:.|.|.:..|..:.|.:|    .:.:| :.|......:
Zfish    32 DPRTVCVSIDEMMSNHV-------SSQQTPLLHAHLKKVENNLTE----AQRFS-YLPRRPAVNI 84

  Fly    70 VWRDLCVYTNVG------GSGQRMKRIINNSTGAIQPGTLMALMGSSGSGKTTLMSTLA-FRQPA 127
            .::||......|      |....:|.|..|.||    |.|:|:||.||:||:|||:.|| :|:
Zfish    85 EFKDLSYSVPEGPWWRKKGYKTLLKGISGNFTG----GALVAIMGPSGAGKSTLMNILAGYRE-- 143

  Fly   128 GTVVQGDILING--RRIGPFMHRISGYVYQDDLFLGSLTVLEHLNFMAHLRLDRRVSKEERRLII 190
             |.::|:|||||  |.:..| .::|.|:.|||:.|..|||.|.:...|:|:|..:  .|.||.::
Zfish   144 -TGMKGEILINGHPRDLRSF-RKVSCYIMQDDMLLPHLTVQEAMMVSANLKLQEK--DEGRREMV 204

  Fly   191 KELLERTGLLSAAQTRIGSGDDKKVLSGGERKRLAFAVELLNNPVILFCDEPTTGLDSYSAQQLV 255
            :|:|...|||..|:||...      ||||:|||||.|:||:|||.::|.||||:||||.|..|:|
Zfish   205 REILTALGLLECAKTRTSH------LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSSSCFQVV 263

  Fly   256 ATLYELAQKGTTILCTIHQPSSQLFDNFNNVMLLADGRVAFTGSPQHALSFFANHGYYCPEAYNP 320
            :.:..|||.|.|::|||||||:::|:.|:.:.:|:.|:..:.|.....:.:..:.|..||..:||
Zfish   264 SLMKALAQGGRTVICTIHQPSAKVFELFDKLYVLSQGQCIYRGKVSSLIPYLRDLGLSCPTYHNP 328

  Fly   321 ADFLIGVLATDPGYEQASQRSA--QHLCDQFAVSSAAKQRDMLVNLE---IHMAQSGNFPFDTEV 380
            |||::.|.:.:.|.:.|....|  :|.|          ::|....:.   :|.....:.|.|.|.
Zfish   329 ADFIMEVASGEYGDQTARLVKAVQEHKC----------EKDYKTEMNGNGVHNPFLWHRPSDEES 383

  Fly   381 ESFRG-----VAWYKRFHVVWLRASLTLLRDPTIQWLRFIQKIAMAFIIGACFAGTTEPSQLGVQ 440
            .|..|     .:...:|.:::.|..|:::||..:..||.:..:.:..:||..:.|....:: .|.
Zfish   384 SSSEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRIMSHLGIGILIGLLYLGIGNEAK-KVL 447

  Fly   441 AVQGALFIMISENTYHPMYSVLNLFPQGFPLFMRETRSGLYSTGQYYAANILALLPGMIIEPLIF 505
            :..|.||..:....:..:...:..||....:|:||..:..||...||.|..:|.:|..|:.|:.:
Zfish   448 SNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMADVPFQIVFPVAY 512

  Fly   506 VIICYWLTGLRSTFYAFGVTAMCVVLVMNVATACGCFFSTAFNSVPLAMAYLVPLDYI-FMITSG 569
            ..|.||:|...|....|.:......|...||.:.|.....|..|:.:| .::.|:..| .::.||
Zfish   513 CSIVYWMTSQPSDAVRFILFLALGTLTSLVAQSLGLLIGAASTSLQVA-TFVGPVTAIPVLLFSG 576

  Fly   570 IFIQVNSLPVAFWWTQFLSWMLYANEAMTAAQWSGVQNITCFQESADLPC-------FHTGQDVL 627
            .|:..:::|....|..::|::.|..|.:..:.:.        .:..||.|       |...:.:|
Zfish   577 FFVSFDTIPKYLQWISYISYVRYGFEGVILSIYG--------LDREDLHCDKDETCHFQKSEAIL 633

  Fly   628 DKYSFNESNVYRNLLAMVGLYF-GFHLLGYYCL 659
            .:....::.:|.:.: ::|::| ...|:.|:.|
Zfish   634 KELDVEDAKLYMDFI-VLGIFFISLRLIAYFVL 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	ABCG_EPDR	66..298	CDD:213180	100/240 (42%)
		3a01204	67..665	CDD:273361	184/621 (30%)
		ABC2_membrane	395..600	CDD:279410	50/205 (24%)
abcg1	NP_001103924.1	3a01204	67..673	CDD:273361	187/641 (29%)
		ABCG_EPDR	81..306	CDD:213180	100/240 (42%)
		ABC2_membrane	403..605	CDD:279410	50/203 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574356
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.750