Protein Alignment st and Abcg4

DIOPT Version :10

• Sequence 1: NP_524108.1
• Gene: st / 39836
• FlyBaseID: FBgn0003515
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_001100286.2
• Gene: Abcg4 / 300664
• RGDID: 1305840
• Length: 646
• Species: Rattus norvegicus
• Alignment Length: 676
• Identity: 194/676 - (28%)
• Similarity: 331/676 - (48%)
• Gaps: 96/676 - (14%)

  Fly    15 ERVEQHELQVMPVGSTIEVPSLDSTPKLSKRNSSERSLPLRSYSKWSPTEQGATLVWRDLCVYTN 79
            ::||.|            :........|.||::.:......|||    ..:|.  .||.
  Rat    38 KKVENH------------ITEAQRFSHLPKRSAVDIEFVELSYS----VREGP--CWRK------ 78

  Fly    80 VGGSGQRMKRIINNSTGAIQPGTLMALMGSSGSGKTTLMSTLAFRQPAGTVVQGDILINGR-RIG 143
                 :..|.::...:|......|:.:||.||:||:|.|:.||..:.:|  ::|.||:||| |..
  Rat    79 -----RGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESG--MKGQILVNGRPRDL 136

  Fly   144 PFMHRISGYVYQDDLFLGSLTVLEHLNFMAHLRLDRRVSKEERRLIIKELLERTGLLSAAQTRIG 208
            ....::|.|:.|||:.|..|||||.:...|:|:|..:  :|.::.::.|:|...||:|.:.||..
  Rat   137 RTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEK--QEVKKELVTEILTALGLMSCSHTRTA 199

  Fly   209 SGDDKKVLSGGERKRLAFAVELLNNPVILFCDEPTTGLDSYSAQQLVATLYELAQKGTTILCTIH 273
                  :||||:|||||.|:||:|||.::|.||||:||||.|..|:|:.:..||..|.|::||||
  Rat   200 ------LLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAHGGRTVICTIH 258

  Fly   274 QPSSQLFDNFNNVMLLADGRVAFTGSPQHALSFFANHGYYCPEAYNPADFLIGVLATDPG-YEQA 337
            |||::||:.|:.:.:|:.|:..|.|...:.:.:....|.:||..:|||||:|.|.:.:.| ....
  Rat   259 QPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPADFIIEVASGEYGDLNPM 323

  Fly   338 SQRSAQH-LCDQFAVSSAAKQRDMLVNL-----EIHMAQSGNFPFDTEVESFRGVAWYKRFHVVW 396
            ..|:.|: ||......|:.::.::..:.     |:...:|..|...|          ..:|.:::
  Rat   324 LFRAVQNGLCTMAEKKSSPEKNEVPAHCPTCPPELDPIESHTFATST----------LTQFCILF 378

  Fly   397 LRASLTLLRDPTIQWLRFIQKIAMAFIIGACFAGTTEPSQLGVQAVQGALFIMISENTYHPMYSV 461
            .|..|::|||..:..|||:..:.:..:||..:.      .:|..|.:      :..||....:|:
  Rat   379 RRTFLSILRDTVLTHLRFMSHVLIGVLIGLLYL------HIGDDASK------VFNNTGFLFFSM 431

  Fly   462 LNL-----------FPQGFPLFMRETRSGLYSTGQYYAANILALLPGMIIEPLIFVIICYWLTGL 515
            |.|           ||....:||||..:..||...||.|..:|.:|..::.|:::..|.||:||.
  Rat   432 LFLMFAALMPTVLTFPLEMAVFMREHLNYWYSLKAYYLAKTMADVPFQVVCPVVYCSIVYWMTGQ 496

  Fly   516 ---RSTFYAFGVTAMCVVLVMNVATACGCFFSTAFNSVPLAMAYLVPLDYI-FMITSGIFIQVNS 576
               .|.|..|...::...|   ||.:.|.....|..|:.:| .::.|:..| .::.||.|:...:
  Rat   497 PAETSRFLLFSALSIATAL---VAQSLGLLIGAASTSLQVA-TFVGPVTAIPVLLFSGFFVSFKT 557

  Fly   577 LPVAFWWTQFLSWMLYANEAMTAAQWSGVQ--NITCFQESADLPCFHTGQDVLDKYSFNESNVYR 639
            :|....|:.:||::.|..|.:....: |::  ::||.::...   |...|.:|.:....|:.:|.
  Rat   558 IPTYLQWSSYLSYVRYGFEGLILTIY-GMERGHLTCLEDHCP---FRDPQIILHELDVEEAKLYM 618

  Fly   640 NLLAMVGLYF-GFHLLGYYCLWRRAR 664
            :.| ::|::| ...||.|..|..|.:
  Rat   619 DFL-VLGIFFLALRLLAYLVLRYRVK 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	3a01204	67..665	CDD:273361	184/624 (29%)
Abcg4	NP_001100286.2	3a01204	44..646	CDD:273361	191/658 (29%)