Protein Alignment st and Abcg5

DIOPT Version :9

• Sequence 1: NP_524108.1
• Gene: st / 39836
• FlyBaseID: FBgn0003515
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_114090.1
• Gene: Abcg5 / 27409
• MGIID: 1351659
• Length: 652
• Species: Mus musculus
• Alignment Length: 560
• Identity: 165/560 - (29%)
• Similarity: 268/560 - (47%)
• Gaps: 56/560 - (10%)

  Fly    79 NVGGSGQRMKR-IINNSTGAIQPGTLMALMGSSGSGKTTLMSTLAFRQPAGTVVQGDILING--R 140
            |:....|:..| |:.:.:..|:.|.:|.::||||||||||:..::.|......::|::.:||  .
Mouse    57 NIKSCQQKWDRQILKDVSLYIESGQIMCILGSSGSGKTTLLDAISGRLRRTGTLEGEVFVNGCEL 121

  Fly   141 RIGPFMHRISGYVYQDDLFLGSLTVLEHLNFMAHLRLDRRVSKEERRLIIKELLERTGLLSAAQT 205
            |...|....| ||.|.|:||.||||.|.|.:.|.|.|.|. |.:.....::.::....|...|..
Mouse   122 RRDQFQDCFS-YVLQSDVFLSSLTVRETLRYTAMLALCRS-SADFYNKKVEAVMTELSLSHVADQ 184

  Fly   206 RIGS---GDDKKVLSGGERKRLAFAVELLNNPVILFCDEPTTGLDSYSAQQLVATLYELAQKGTT 267
            .|||   |.    :|.|||:|::.|.:||.:|.::..||||||||..:|.|:|..|.|||::...
Mouse   185 MIGSYNFGG----ISSGERRRVSIAAQLLQDPKVMMLDEPTTGLDCMTANQIVLLLAELARRDRI 245

  Fly   268 ILCTIHQPSSQLFDNFNNVMLLADGRVAFTGSPQHALSFFANHGYYCPEAYNPADFLIGVLATDP 332
            ::.|||||.|:||.:|:.:.:|..|.:.|.|:|:..|.||.|.||.|||..||.||.:.:.:.|
Mouse   246 VIVTIHQPRSELFQHFDKIAILTYGELVFCGTPEEMLGFFNNCGYPCPEHSNPFDFYMDLTSVD- 309

  Fly   333 GYEQASQRSAQHLCDQFAVSSAAKQRD----MLVNLE--IHMAQSGNFPFDTEVESFRGVAWYKR 391
              .|:.:|..:.......:..|.|:.|    :|.|:|  .::......||.|:...    ..:.:
Mouse   310 --TQSREREIETYKRVQMLECAFKESDIYHKILENIERARYLKTLPTVPFKTKDPP----GMFGK 368

  Fly   392 FHVVWLRASLTLLRDPTIQWLRFIQKIAMA-FIIGACFAGTTEPSQLGVQAVQGALFIMISENTY 455
            ..|:..|.:..|:|:.....:|.:|.:.|. |:|...........:..||...|.|:.::....|
Mouse   369 LGVLLRRVTRNLMRNKQAVIMRLVQNLIMGLFLIFYLLRVQNNTLKGAVQDRVGLLYQLVGATPY 433

  Fly   456 HPMYSVLNLFPQGFPLFMRETRSGLYSTGQYYAANILALLPGMIIEPLIFVIICYWLTGLRSTFY 520
            ..|.:.:||||....:..:|::.|||...|...|.:|.:||..:|..:||..:|||..||.....
Mouse   434 TGMLNAVNLFPMLRAVSDQESQDGLYHKWQMLLAYVLHVLPFSVIATVIFSSVCYWTLGLYPEVA 498

  Fly   521 AFG---------------VTAMCVVLVMNVATACGCFFSTAFNSVPLAMAYLVPLDYIFMITSGI 570
            .||               :|.:.:.:|.|         ....||: :|:..:..|    :|.||.
Mouse   499 RFGYFSAALLAPHLIGEFLTLVLLGIVQN---------PNIVNSI-VALLSISGL----LIGSGF 549

  Fly   571 FIQVNSLPVAFWWTQFLSWMLYANEAMTAAQWSGVQNITC 610
            ...:..:|:......:.::..|..|.:...::.|: |.||
Mouse   550 IRNIQEMPIPLKILGYFTFQKYCCEILVVNEFYGL-NFTC 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	ABCG_EPDR	66..298	CDD:213180	83/224 (37%)
		3a01204	67..665	CDD:273361	165/560 (29%)
		ABC2_membrane	395..600	CDD:279410	50/220 (23%)
Abcg5	NP_114090.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25
		ABCG_White	50..276	CDD:213201	83/224 (37%)
		3a01204	61..646	CDD:273361	164/556 (29%)
		ABC2_membrane	372..579	CDD:279410	50/220 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	90	1.000	Domainoid score	I7740
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3467
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.870