Protein Alignment st and Abcg2

DIOPT Version :9

• Sequence 1: NP_524108.1
• Gene: st / 39836
• FlyBaseID: FBgn0003515
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_001342406.1
• Gene: Abcg2 / 26357
• MGIID: 1347061
• Length: 657
• Species: Mus musculus
• Alignment Length: 600
• Identity: 174/600 - (28%)
• Similarity: 299/600 - (49%)
• Gaps: 43/600 - (7%)

  Fly    88 KRIINNSTGAIQPGTLMALMGSSGSGKTTLMSTLAFRQ-PAGTVVQGDILINGRRIGPFMHRISG 151
            |.|:::..|.::|| |.|::|.:|.||::|:..||.|: |.|  :.||:||||..........||
Mouse    60 KEILSDINGIMKPG-LNAILGPTGGGKSSLLDVLAARKDPKG--LSGDVLINGAPQPAHFKCCSG 121

  Fly   152 YVYQDDLFLGSLTVLEHLNFMAHLRLDRRVSKEERRLIIKELLERTGLLSAAQTRIGSGDDKKVL 216
            ||.|||:.:|:|||.|:|.|.|.|||...:...|:...|..:::..||...|.:::|: ...:.:
Mouse   122 YVVQDDVVMGTLTVRENLQFSAALRLPTTMKNHEKNERINTIIKELGLEKVADSKVGT-QFIRGI 185

  Fly   217 SGGERKRLAFAVELLNNPVILFCDEPTTGLDSYSAQQLVATLYELAQKGTTILCTIHQPSSQLFD 281
            |||||||.:..:||:.:|.|||.|||||||||.:|..::..|..::::|.||:.:||||...:|.
Mouse   186 SGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFK 250

  Fly   282 NFNNVMLLADGRVAFTGSPQHALSFFANHGYYCPEAYNPADFLIGVLATDPGYEQASQRSAQHLC 346
            .|:::.|||.|::.|.|..|.||.:||:.||:|....|||||.:.|:..|......::....:..
Mouse   251 LFDSLTLLASGKLVFHGPAQKALEYFASAGYHCEPYNNPADFFLDVINGDSSAVMLNREEQDNEA 315

  Fly   347 DQFAVSSAAKQRDMLVNLE---IHMAQSGNFPFDTE----VESFRGVAWYKR--------FHVVW 396
            ::....|.. ::.::.||.   |:.|..|....:.:    .:..:|.:.:|.        ..:.|
Mouse   316 NKTEEPSKG-EKPVIENLSEFYINSAIYGETKAELDQLPGAQEKKGTSAFKEPVYVTSFCHQLRW 379

  Fly   397 L--RASLTLLRDPTIQWLRFIQKIAMAFIIGACFAGTTEPSQLGVQAVQGALFIMISENTYHPMY 459
            :  |:...||.:|.....:.|..:.:..||||.:. ..:....|:|...|.||.:.:...:..:
Mouse   380 IARRSFKNLLGNPQASVAQLIVTVILGLIIGAIYF-DLKYDAAGMQNRAGVLFFLTTNQCFSSV- 442

  Fly   460 SVLNLFPQGFPLFMRETRSGLYSTGQYYAANILA-LLPGMIIEPLIFVIICYWLTGLRSTFYAFG 523
            |.:.||.....||:.|..||.|....|:...::: |||...:..:||..|.|::.||:.|..||.
Mouse   443 SAVELFVVEKKLFIHEYISGYYRVSSYFFGKVMSDLLPMRFLPSVIFTCILYFMLGLKKTVDAFF 507

  Fly   524 VTAMCVVLVMNVATACGCFFSTAFNSVPLAMAYLVPLDYIF-MITSGIFIQVNSLPVAFWWTQFL 587
            :....:::|...|::.....:|..:.|.:| ..|:.:.::| |:.||:.:.:.::.....|.|:.
Mouse   508 IMMFTLIMVAYTASSMALAIATGQSVVSVA-TLLMTIAFVFMMLFSGLLVNLRTIGPWLSWLQYF 571

  Fly   588 SWMLYANEAMTAAQWSG---------VQNITCFQESADLPCFHTGQDVLDKYSFNES--NVYRNL 641
            |...|...|:...::.|         ..|.||....|    ..||.:.|.......|  .:::|.
Mouse   572 SIPRYGFTALQYNEFLGQEFCPGFNVTDNSTCVNSYA----ICTGNEYLINQGIELSPWGLWKNH 632

  Fly   642 LAMVGLYFGFHLLGY 656
            :|:..:...|..:.|
Mouse   633 VALACMIIIFLTIAY 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	ABCG_EPDR	66..298	CDD:213180	85/210 (40%)
		3a01204	67..665	CDD:273361	173/599 (29%)
		ABC2_membrane	395..600	CDD:279410	52/208 (25%)
Abcg2	NP_001342406.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24
		3a01204	46..651	CDD:273361	173/599 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831366
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.750