Protein Alignment st and ABCA3

DIOPT Version :9

• Sequence 1: NP_524108.1
• Gene: st / 39836
• FlyBaseID: FBgn0003515
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_001080.2
• Gene: ABCA3 / 21
• HGNCID: 33
• Length: 1704
• Species: Homo sapiens
• Alignment Length: 530
• Identity: 123/530 - (23%)
• Similarity: 206/530 - (38%)
• Gaps: 107/530 - (20%)

  Fly    37 DSTPKLSKRNSSERSLPLRSYSKWSPTEQGATLVWRDLCVYTNVGGSGQRMKRIINNSTGAIQPG 101
            ||.|:.:.||         .|.:..|.:..|.:..:.|.....||...:...|.:|.:   :..|
Human   507 DSDPEKALRN---------EYFEAEPEDLVAGIKIKHLSKVFRVGNKDRAAVRDLNLN---LYEG 559

  Fly   102 TLMALMGSSGSGKTTLMSTLAFRQPAGTVVQGDILINGRRIGPFMHRIS---GYVYQDDLFLGSL 163
            .:..|:|.:|:||||.:|.|....|.   ..|...|:|..|...|.:|.   |...|.|:...:|
Human   560 QITVLLGHNGAGKTTTLSMLTGLFPP---TSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDNL 621

  Fly   164 TVLEHLNFMAHLR-LDRRVSKEERRLIIKELLERTGLLSAAQTRIGSGDDKKVLSGGERKRLAFA 227
            ||.|||.|.|.|: |.|:...||    :|::|...||.....:|      .:.||||.|::|:..
Human   622 TVAEHLYFYAQLKGLSRQKCPEE----VKQMLHIIGLEDKWNSR------SRFLSGGMRRKLSIG 676

  Fly   228 VELLNNPVILFCDEPTTGLDSYSAQQLVATLYELAQKGTTILCTIHQPSSQLFDNFNNVMLLADG 292
            :.|:....:|..||||:|:|:.|.:.:...|.......|.:|.|.....:.|..  :.:.::|.|
Human   677 IALIAGSKVLILDEPTSGMDAISRRAIWDLLQRQKSDRTIVLTTHFMDEADLLG--DRIAIMAKG 739

  Fly   293 RVAFTGSPQHALSFFANHGY------------YCPEAYNPADFLIGVLATDPGYEQASQRSAQHL 345
            .:...||     |.|....|            :|    ||.|.              ||....|:
Human   740 ELQCCGS-----SLFLKQKYGAGYHMTLVKEPHC----NPEDI--------------SQLVHHHV 781

  Fly   346 CDQFAVSSAAKQRDMLVNLEIHMAQSGNFPFDTEVESFRGVAWY----KRFHVVWLRA------- 399
            .:....|||..:...::..|......|.|....:.:...|:|.:    .....|:||.
Human   782 PNATLESSAGAELSFILPRESTHRFEGLFAKLEKKQKELGIASFGASITTMEEVFLRVGKLVDSS 846

  Fly   400 -SLTLLRDPTIQWLRFIQKIAMAFIIGACFAGTTEPSQLGVQAVQGALFIMISENTYHPMYSVLN 463
             .:..::.|.:|:..  ::.|..:.:.:...|..:||. |:    |||  :..|.|...:.:.|.
Human   847 MDIQAIQLPALQYQH--ERRASDWAVDSNLCGAMDPSD-GI----GAL--IEEERTAVKLNTGLA 902

  Fly   464 LFPQGF-PLFMRETRSGLYSTGQYYAANILALLPGMIIEPLIFVIICYWLTG----------LRS 517
            |..|.| .:|:::   ..||..::      .::...::.||..|.:......          ||.
Human   903 LHCQQFWAMFLKK---AAYSWREW------KMVAAQVLVPLTCVTLALLAINYSSELFDDPMLRL 958

  Fly   518 TFYAFGVTAM 527
            |...:|.|.:
Human   959 TLGEYGRTVV 968

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	ABCG_EPDR	66..298	CDD:213180	66/235 (28%)
		3a01204	67..665	CDD:273361	116/500 (23%)
		ABC2_membrane	395..600	CDD:279410	30/152 (20%)
ABCA3	NP_001080.2	ABC2_membrane_3	<271..469	CDD:289468
		CcmA	530..839	CDD:224054	87/349 (25%)
		ABC_subfamily_A	530..751	CDD:213230	69/243 (28%)
		ABC2_membrane_3	923..1261	CDD:289468	8/52 (15%)
		ABC_subfamily_A	1381..1602	CDD:213230
		drrA	1397..1692	CDD:130256

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910