Protein Alignment st and Abcg4

DIOPT Version :9

• Sequence 1: NP_524108.1
• Gene: st / 39836
• FlyBaseID: FBgn0003515
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_620405.3
• Gene: Abcg4 / 192663
• MGIID: 1890594
• Length: 646
• Species: Mus musculus
• Alignment Length: 677
• Identity: 195/677 - (28%)
• Similarity: 330/677 - (48%)
• Gaps: 98/677 - (14%)

  Fly    15 ERVEQHELQVMPVGSTIEVPSLDSTPKLSKRNSSERSLPLRSYSKWSPTEQGATLVWRDLCVYTN 79
            ::||.|            :........|.||::.:......|||    ..:|.  .||.
Mouse    38 KKVENH------------ITEAQRFSHLPKRSAVDIEFVELSYS----VREGP--CWRK------ 78

  Fly    80 VGGSGQRMKRIINNSTGAIQPGTLMALMGSSGSGKTTLMSTLAFRQPAGTVVQGDILING--RRI 142
                 :..|.::...:|......|:.:||.||:||:|.|:.||..:.:|  ::|.||:||  |.:
Mouse    79 -----RGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESG--MKGQILVNGRPREL 136

  Fly   143 GPFMHRISGYVYQDDLFLGSLTVLEHLNFMAHLRLDRRVSKEERRLIIKELLERTGLLSAAQTRI 207
            ..| .::|.|:.|||:.|..|||||.:...|:|:|..:  :|.::.::.|:|...||:|.:.||.
Mouse   137 RTF-RKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEK--QEVKKELVTEILTALGLMSCSHTRT 198

  Fly   208 GSGDDKKVLSGGERKRLAFAVELLNNPVILFCDEPTTGLDSYSAQQLVATLYELAQKGTTILCTI 272
            .      :||||:|||||.|:||:|||.::|.||||:||||.|..|:|:.:..||..|.|::|||
Mouse   199 A------LLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAHGGRTVICTI 257

  Fly   273 HQPSSQLFDNFNNVMLLADGRVAFTGSPQHALSFFANHGYYCPEAYNPADFLIGVLATDPG-YEQ 336
            ||||::||:.|:.:.:|:.|:..|.|...:.:.:....|.:||..:|||||:|.|.:.:.| ...
Mouse   258 HQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPADFIIEVASGEYGDLNP 322

  Fly   337 ASQRSAQH-LCDQFAVSSAAKQRDMLVNL-----EIHMAQSGNFPFDTEVESFRGVAWYKRFHVV 395
            ...|:.|: ||......|:..:.::..:.     |:...:|..|...|          ..:|.::
Mouse   323 MLFRAVQNGLCTMAEKKSSPGKNELPAHCPTCPPELDPIESHTFATST----------LTQFCIL 377

  Fly   396 WLRASLTLLRDPTIQWLRFIQKIAMAFIIGACFAGTTEPSQLGVQAVQGALFIMISENTYHPMYS 460
            :.|..|::|||..:..|||:..:.:..:||..:.      .:|..|.:      :..||....:|
Mouse   378 FRRTFLSILRDTVLTHLRFMSHVLIGVLIGLLYL------HIGDDASK------VFNNTGFLFFS 430

  Fly   461 VLNL-----------FPQGFPLFMRETRSGLYSTGQYYAANILALLPGMIIEPLIFVIICYWLTG 514
            :|.|           ||....:||||..:..|:...||.|..:|.:|..::.|:::..|.||:||
Mouse   431 MLFLMFAALMPTVLTFPLEMAVFMREHLNYWYTLKAYYLAKTMADVPFQVVCPVVYCSIVYWMTG 495

  Fly   515 L---RSTFYAFGVTAMCVVLVMNVATACGCFFSTAFNSVPLAMAYLVPLDYI-FMITSGIFIQVN 575
            .   .|.|..|...|:...|   ||.:.|.....|..|:.:| .::.|:..| .::.||.|:...
Mouse   496 QPAETSRFLLFSALAIATAL---VAQSLGLLIGAASTSLQVA-TFVGPVTAIPVLLFSGFFVSFK 556

  Fly   576 SLPVAFWWTQFLSWMLYANEAMTAAQWSGVQ--NITCFQESADLPCFHTGQDVLDKYSFNESNVY 638
            ::|....|:.:||::.|..|.:....: |::  ::||..|...   |...|.:|.:....|:.:|
Mouse   557 TIPTYLQWSSYLSYVRYGFEGLILTIY-GMERGHLTCLDEQCP---FRDPQIILRELDVEEAKLY 617

  Fly   639 RNLLAMVGLYF-GFHLLGYYCLWRRAR 664
            .:.| ::|::| ...||.|..|..|.:
Mouse   618 MDFL-VLGIFFLALRLLAYLVLRYRVK 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	ABCG_EPDR	66..298	CDD:213180	90/233 (39%)
		3a01204	67..665	CDD:273361	185/625 (30%)
		ABC2_membrane	395..600	CDD:279410	57/219 (26%)
Abcg4	NP_620405.3	3a01204	44..646	CDD:273361	192/659 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831362
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.740