Protein Alignment st and ABCA1

DIOPT Version :9

• Sequence 1: NP_524108.1
• Gene: st / 39836
• FlyBaseID: FBgn0003515
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_005493.2
• Gene: ABCA1 / 19
• HGNCID: 29
• Length: 2261
• Species: Homo sapiens
• Alignment Length: 359
• Identity: 86/359 - (23%)
• Similarity: 158/359 - (44%)
• Gaps: 57/359 - (15%)

  Fly    85 QRMKRIINNSTGAIQPGTLMALMGSSGSGKTTLMSTLAFRQPAG--TVVQGDILINGRRIGPFMH 147
            ::.|..::.....|.||....|:|.:|:||::     .|:...|  ||.:||..:|...|...:|
Human  1923 RKRKPAVDRICVGIPPGECFGLLGVNGAGKSS-----TFKMLTGDTTVTRGDAFLNKNSILSNIH 1982

  Fly   148 RI---SGYVYQDDLFLGSLTVLEHLNFMAHLRLDRRVSKEERRLIIKELLERTGLLSAAQTRIGS 209
            .:   .||..|.|.....||..||:.|.|.|   |.|.::|...:.:..:.:.||:...:...|:
Human  1983 EVHQNMGYCPQFDAITELLTGREHVEFFALL---RGVPEKEVGKVGEWAIRKLGLVKYGEKYAGN 2044

  Fly   210 GDDKKVLSGGERKRLAFAVELLNNPVILFCDEPTTGLDSYSAQQLVATLYELAQKGTTILCTIHQ 274
                  .|||.:::|:.|:.|:..|.::|.||||||:|..:.:.|......:.::|.:::.|.|.
Human  2045 ------YSGGNKRKLSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALSVVKEGRSVVLTSHS 2103

  Fly   275 PSSQLFDNFNNVMLLADGRVAFTGSPQHALSFFANHGYYC--------PEAYNPADFLIGVLATD 331
             ..:.......:.::.:||....||.||..:.|.: ||..        |:.....|| .|:  ..
Human  2104 -MEECEALCTRMAIMVNGRFRCLGSVQHLKNRFGD-GYTIVVRIAGSNPDLKPVQDF-FGL--AF 2163

  Fly   332 PG------------YEQASQRSAQHLCDQFAVSSAAKQRDMLVNLEIHMAQSG-------NFPFD 377
            ||            |:..|..|:  |...|::.|.:|:|   :::|.:.....       ||..|
Human  2164 PGSVLKEKHRNMLQYQLPSSLSS--LARIFSILSQSKKR---LHIEDYSVSQTTLDQVFVNFAKD 2223

  Fly   378 -TEVESFRGVAWYKRFHVVWLRASLTLLRDPTIQ 410
             ::.:..:.::.:|...||.:....:.|:|..::
Human  2224 QSDDDHLKDLSLHKNQTVVDVAVLTSFLQDEKVK 2257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	ABCG_EPDR	66..298	CDD:213180	56/217 (26%)
		3a01204	67..665	CDD:273361	86/359 (24%)
		ABC2_membrane	395..600	CDD:279410	3/16 (19%)
ABCA1	NP_005493.2	rim_protein	6..2236	CDD:130324	81/336 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1283..1312

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910