Protein Alignment st and wht-6

DIOPT Version :9

• Sequence 1: NP_524108.1
• Gene: st / 39836
• FlyBaseID: FBgn0003515
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_498425.2
• Gene: wht-6 / 188911
• WormBaseID: WBGene00007060
• Length: 613
• Species: Caenorhabditis elegans
• Alignment Length: 620
• Identity: 203/620 - (32%)
• Similarity: 325/620 - (52%)
• Gaps: 63/620 - (10%)

  Fly    68 TLVWRDLCVYTNVGGSGQRMKRIINNSTGAIQPGTLMALMGSSGSGKTTLMSTLAFRQPAGTVVQ 132
            :|.|.::.|.|.     :..:.::.|.:|..:.|.|:||||:||:|||||::.|..|...|...:
 Worm    33 SLHWNNITVTTI-----KEKRLLLKNVSGYAKSGELLALMGASGAGKTTLLNMLMCRNLKGLSTE 92

  Fly   133 GDILINGRRIGPFMHRISGYVYQDDLFLGSLTVLEHLNFMAHLRLDRRVSKEERRLIIKELLERT 197
            |.|.:||..:...:..|||:..|::||:|:|||.|:|...|.||::.  ||:.|...:.::|.:.
 Worm    93 GTITVNGNEMAHKISSISGFAQQEELFVGTLTVKEYLMIQAKLRING--SKKLREDRVTDVLHQL 155

  Fly   198 GLLSAAQTRIGSGDDKKVLSGGERKRLAFAVELLNNPVILFCDEPTTGLDSYSAQQLVATLYELA 262
            .|.....::||...:||.:||||.:||.||.|:|:||.:||.|||||||||:.|:.::..|..:|
 Worm   156 KLWKCRDSKIGVIGEKKGISGGEARRLTFACEMLSNPSLLFADEPTTGLDSFMAESVIQILKGIA 220

  Fly   263 QKGTTILCTIHQPSSQLFDNFNNVMLLADGRVAFTGSPQHALSFFANHGYYCPEAYNPADFLIGV 327
            :.|.||:||||||||||:..|:.|:.||:|..||.|:||.::|||...|:..|:.|||::::|..
 Worm   221 KTGRTIICTIHQPSSQLYQMFHRVIYLANGSTAFQGTPQESISFFEKCGHRVPDEYNPSEWIIYK 285

  Fly   328 LATDPGYEQASQRSAQHLCDQFAVSSAAKQ-RDMLVNL-------EIHMAQSGNFPFDTEVESFR 384
            ||..||.|:.|....|.:.:|:..|...|: .:.|.::       |:|.|..
 Worm   286 LAVQPGQEKQSNDRIQKIVEQYEDSDHQKRVMEQLSDVSEKIPPPEMHRANV------------- 337

  Fly   385 GVAWYKRFHVVWLRASLTLLRDPTIQWLRFIQKIAMAFIIGACFAGTTEPSQLGVQAVQGALFIM 449
                :.:...:..|..:.:.|.|.:...:.||||.....||..:..|...:: |:..:.||||.:
 Worm   338 ----FTQIFALSTRCGIDVWRAPQLTLAKVIQKILFGLFIGLLYLRTPYDAR-GIHNINGALFFL 397

  Fly   450 ISENTYHPMYSVLNLFPQGFPLFMRETRSGLYSTGQYYAANILALLPGMIIEPLIFVIICYWLTG 514
            ..|..|...|:::......|||..||...|||:...||.|..::|:|....:.||.:.|.|||.|
 Worm   398 AGEYIYSTAYAIMFFLNNEFPLVAREYHDGLYNLWTYYFARCISLIPLFSTDGLILLFIVYWLIG 462

  Fly   515 LRSTFYAFGVTAMCVVLVMNVATACG----CFFSTAFNSVPLAMAYLVPLDYIFMITSGIFIQVN 575
            |.::.....|.::..||....|:|.|    |.|.||..:..:|...||    :|.:..|::...|
 Worm   463 LNTSVMQVIVASIITVLASQAASAFGIAMSCIFPTAQMTAVMASPPLV----LFRLFGGLYGNTN 523

  Fly   576 SLPVAFWWTQFLSWMLYANEAMTAAQWSGVQNITCFQESADLPCFH----------TGQDVLDKY 630
            :.|.|..|.|::|...:|.|.:...|||.:.:            ||          |..||||.:
 Worm   524 TFPAAIRWLQWISMYRFAFEGLVVNQWSEIDD------------FHSNAKNNWTNSTTNDVLDYF 576

  Fly   631 SFNESNVYRNLLAMVGLYFGFHLLGYYCLWRRARK 665
            :|:||.:..:::.::.:...|:|:|:..|..|.:|
 Worm   577 AFSESAIPLDIIGLILISLAFYLIGFIALVHRMKK 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	ABCG_EPDR	66..298	CDD:213180	96/229 (42%)
		3a01204	67..665	CDD:273361	202/618 (33%)
		ABC2_membrane	395..600	CDD:279410	62/208 (30%)
wht-6	NP_498425.2	P-loop_NTPase	<3..>81	CDD:393306	19/52 (37%)
		3a01204	50..613	CDD:273361	199/598 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H104214
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3467
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.730