DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment st and AgaP_AGAP013384

DIOPT Version :9

Sequence 1:	NP_524108.1	Gene:	st / 39836	FlyBaseID:	FBgn0003515	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	XP_003436017.1	Gene:	AgaP_AGAP013384 / 11175676	VectorBaseID:	AGAP013384	Length:	791	Species:	Anopheles gambiae

Alignment Length:	481	Identity:	94/481 - (19%)
Similarity:	158/481 - (32%)	Gaps:	128/481 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 GGSGQRMKRIINNSTGAIQPGTLMALMGSSGSGKTTLMSTLAFRQPAGTVVQGDILINGRRIGPF 145
            ||||.      .:|:....|.::.:  .:|||..:|..   |...||  ||.|.        .|.
Mosquito    36 GGSGS------ESSSSPSAPSSISS--STSGSSASTCE---AASPPA--VVTGQ--------PPS 79

  Fly   146 MHRISGYVYQDDLFLGSLTVLEHLNFMAHLRLDRRVSKEERRLIIKELLERTGLLSA------AQ 204
            :.::   :|..   :|...:.|.|. ...::.|..:|.||...:: ::||.|....|      .:
Mosquito    80 VAQV---LYMP---VGLANIKEELP-EPEIQADSELSLEEGHALV-QVLEDTPNDEAPPPEPEVE 136

  Fly   205 TRIGSGDD--KKVLSGG--------------------ERKRLAFAVELLNNPVILFCDEPTTGL- 246
            .|.|..|.  :|:.|.|                    ::...:.|:..::||::|..|:....:
Mosquito   137 IRAGKADKSFRKLTSDGYPAKGAVVRLQMGKVTYQLTDQMLKSGALAAMHNPLLLTKDQLERMIS 201

  Fly   247 ------------DSYSAQQLVATLYELAQKGTTILC------TIHQPSS---QLFDNFNNVMLLA 290
                        ::.|..|....:|....|...:.|      .:|:.|:   .|..:...:.|.:
Mosquito   202 DKDPELEYRKHHNNNSTWQRYMPMYYKGIKQNYVRCLECGWLVLHKASTGTGSLLRHRCKIKLPS 266

  Fly   291 DGRVAFTGSPQHALSFFANHGYYCPEAYNPADFLIGVLATDPGYEQASQRSAQHLCDQFAVSSAA 355
            ...|..  .|:.:.|:.::.|...|.|...|..:.......|....:|.          ||::..
Mosquito   267 GVEVKL--EPKVSSSWNSSQGGKAPAAPKSATAIGAAKVVQPAAPPSST----------AVTTTP 319

  Fly   356 KQRDMLVNLEIHMAQSGNFPFDTEVESFRGVA--WYKRFHVVWLRASLTLLRDPTIQWLRFIQKI 418
            .|.         :...|..|.:.:.|..|..|  .||..      .|..|...|:.:.|     .
Mosquito   320 PQM---------VKYGGVLPQNVKDELVRQQACVLYKDI------VSADLFDQPSFRTL-----A 364

  Fly   419 AMAFIIGACFAGTTEPSQLGVQAVQGALFIMISENTYHPMYSVLNL------FPQGFPLFMRETR 477
            .|...|||.:.  .:|.  |:.|.:.||...:....||.....||.      ....|.||..|
Mosquito   365 QMLVNIGAFYG--QQPD--GLLASRDALLETVLPAMYHEAKGQLNKVLSDCDLTFSFSLFRHE-- 423

  Fly   478 SGLYSTGQYYAANILALLPGMIIEPL 503
               :....|.|.|...:.......||
Mosquito   424 ---HERRTYVAINAYTVASDYYFRPL 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	ABCG_EPDR	66..298	CDD:213180	50/266 (19%)
		3a01204	67..665	CDD:273361	94/481 (20%)
		ABC2_membrane	395..600	CDD:279410	26/115 (23%)
AgaP_AGAP013384	XP_003436017.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910