Protein Alignment st and abcg8

DIOPT Version :9

• Sequence 1: NP_524108.1
• Gene: st / 39836
• FlyBaseID: FBgn0003515
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: XP_031758486.1
• Gene: abcg8 / 100498405
• XenbaseID: XB-GENE-981625
• Length: 682
• Species: Xenopus tropicalis
• Alignment Length: 704
• Identity: 185/704 - (26%)
• Similarity: 318/704 - (45%)
• Gaps: 108/704 - (15%)

  Fly    18 EQHELQVMPVGSTIEVPSLDSTPKLSKRNSSERSLPLRSYSKWSPTEQGA--TLVWRDLCVYTNV 80
            :|.:.|::|       |||        |.:.:..||....|.:. |..||  .|..:||....|:
 Frog    14 KQDQFQMLP-------PSL--------RRNDDLYLPEEDNSLYF-TYSGAPNVLEVKDLTYQVNL 62

  Fly    81 G---------------------GSGQRMKRIINNSTGAIQPGTLMALMGSSGSGKTTLMSTLAFR 124
            .                     |....||    |....:..|.::|::|::|.|||:|:..:..:
 Frog    63 NAQIPWYEKLAEFKMPWEWNKDGQISAMK----NINVKVTSGQMLAVIGNTGCGKTSLLDIITCK 123

  Fly   125 QPAGTVVQGDILINGRRIGPFMHRIS---GYVYQDDLFLGSLTVLEHLNFMAHLRLDRRVSKEER 186
            ...|.:..|.|||||:  ....||:.   .:|.|||..|..|||.|.|.|:|.|||.:..|:|:|
 Frog   124 DEGGKIKSGQILINGK--VSTKHRVKKCVAHVRQDDQLLPHLTVRETLTFIAKLRLPKSYSEEQR 186

  Fly   187 RLIIKELLERTGLLSAAQTRIGSGDDKKVLSGGERKRLAFAVELLNNPVILFCDEPTTGLDSYSA 251
            |..:::::....|...|.|::|:...:.| |||||:|::..|:||.||.||..||||:||||::|
 Frog   187 RRQVEDVIAELRLRQCANTKVGNTYTRGV-SGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTA 250

  Fly   252 QQLVATLYELAQKGTTILCTIHQPSSQLFDNFNNVMLLADGRVAFTGSPQHALSFFANHGYYCPE 316
            ..||.||..||:....:|.:||||.|.:|..|:.|:||:.|...::|:.:..:.:|::.||.||.
 Frog   251 HNLVITLSRLARGNRLVLLSIHQPRSDIFQLFDLVLLLSSGATIYSGTAKDMVEYFSSIGYPCPR 315

  Fly   317 AYNPADFLIGVLATDPGYEQASQRSAQHL----------------CDQFAVSSAAKQRDML---- 361
            ..|||||.:.:.:.|   ::..:|..:.|                .|.|......:....:
 Frog   316 YSNPADFYVDLTSID---QRNKERETESLERTRSLAEIFWEKVKDSDDFLWKPPGEANKNITPTN 377

  Fly   362 --VNLEIHMAQSGNFPFDTEVESF-RGVAWYKRFHVVWLRASLTLLRDPTIQWLRFIQKIAMAFI 423
              :||.:...:......:::::.. ||:   .:|.|:..|.....|||.:...:...:.:.||.:
 Frog   378 TSINLPVSAHEKAIKIKNSDMDQLPRGL---HQFSVLLRRHVSNDLRDLSTLLIHGFEALVMALL 439

  Fly   424 IGACFAGTTEPSQLGVQAVQGALFIMISENTYHPMYSVLNLFPQGFPLFMRETRSGLYSTGQYYA 488
            ||..:.|... :||.:|.....||:..|...:..:..|:........:...:...||||...|:.
 Frog   440 IGFLYYGQGN-NQLSIQDSIALLFMKGSLTPFAVVLDVVAKCHSERAMLYHDLEDGLYSVTPYFF 503

  Fly   489 ANILALLPGMIIEPLIFVII----CYWLTGLRSTFYAFGVTAMCVVLVMNVATACGCFFSTAFNS 549
            |.::..||    |...|||.    .|||..|......|.:....::|::..:.|...:.|....:
 Frog   504 AKVIGELP----EHFAFVIFYGVPIYWLANLNPHPECFLLNFALLLLIVYCSRAMALWMSALLPT 564

  Fly   550 VPLAMAYLVPLDYIF---MITSGIFIQVNSLPVAFWWTQFLSWMLYANEAMTAAQWSG------V 605
            :.:: ::|  .:.||   .:|.|..|::.:|....:|..::|::.:..|.:...|::.      |
 Frog   565 LQMS-SFL--SNAIFTSSYLTGGFIIRLENLWTVPYWISYVSFLRWGFEGLMQVQFTDLSYKVPV 626

  Fly   606 QNITCFQESADLPCFHTGQDVLDKYSFNESNVYRNLLAMVGLYFGFHLLGYYCL 659
            .|||     ..:|    |..::.....:...:|.:.|.::|:..||.:|.|..|
 Frog   627 GNIT-----ITIP----GTAIISNMEMDSHPLYASYLVLIGIIAGFLVLYYLSL 671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	ABCG_EPDR	66..298	CDD:213180	91/257 (35%)
		3a01204	67..665	CDD:273361	173/655 (26%)
		ABC2_membrane	395..600	CDD:279410	46/211 (22%)
abcg8	XP_031758486.1	3a01204	61..672	CDD:273361	169/641 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010