Protein Alignment CG43373 and gucy1a1

DIOPT Version :9

• Sequence 1: NP_001097622.2
• Gene: CG43373 / 39835
• FlyBaseID: FBgn0263131
• Length: 1854
• Species: Drosophila melanogaster
• Sequence 2: NP_001296458.1
• Gene: gucy1a1 / 550420
• ZFINID: ZDB-GENE-050417-230
• Length: 679
• Species: Danio rerio
• Alignment Length: 474
• Identity: 114/474 - (24%)
• Similarity: 190/474 - (40%)
• Gaps: 139/474 - (29%)

  Fly   460 GGRSAGS------KHITYTPRVRDYNQI------SHAERDEVLNTSSNAGVATDNSDPPLGYGQL 512
            ||:.:|:      .|:.|:..|||...:      :|...|
Zfish   239 GGKDSGALQADHQPHLLYSVVVRDGRSLTPSPMRTHTSGD------------------------- 278

  Fly   513 IPLILMQVDESVLVFLIVM--------LICGIVYAFLLCI--LSKPAMNEIFLVLVSYV------ 561
            |||.|:.   |...|.|::        :..|:......|.  ..:||.||.|.::...:
Zfish   279 IPLSLLY---STFPFHILLDQEMGLLQIGDGLRRRLGRCRDGQRRPAFNEHFAIVSPEIRASFQD 340

  Fly   562 ---ILGTFLAIEV---AVSYAMQPSKS-----------------FNGSACCIVLIYMTYTMLPLR 603
               :|.|...:.|   ..|.|..|.|.                 |.||.|...|
Zfish   341 ILTMLNTQFLLRVKQHGASSADSPGKHMDLKGQMIFMSEMSALLFLGSPCVDKL----------- 394

  Fly   604 LREALIG-GILLSVVHLYTCLRLNAMQDEAVEMIHWEELLCTLVALLLANLTGVYTHWPKEKAQR 667
              |.|.| |:.||.:.::     ||::|                .:|:...|.......|...:.
Zfish   395 --EELTGRGLYLSDIPIH-----NALRD----------------VVLVGEQTKAQDGLKKRLGKA 436

  Fly   668 KAFIETRQCIEARLRTQRENQQQERLLLSVLPRHVAMEMKDDIAGQPRDTQFHKIYIQRHENVSI 732
            ||.:|     :|....:.|.::...||.::.|.:||..:..   |.|       :..::.::|::
Zfish   437 KAALE-----QAHQALEEEKRRTVELLFTIFPGNVAQRLWQ---GLP-------VQAKKFDHVTV 486

  Fly   733 LFADICGFTSLSDQCTAEELVRLLNELFARFDRLAAEHHC-----LRIKLLGDCYYCVSGLPEPR 792
            ||:||.|||::..:||..::|.:|:||:.|||     |||     .:::.:||.|....||.:..
Zfish   487 LFSDIVGFTAICSRCTPMQVVNMLSELYTRFD-----HHCGELDVYKVETIGDAYCVAGGLHKES 546

  Fly   793 PDHAHCAVEMGLDMIDAIALVREVMAVNVNMRVGIHTGRVHCGVLGLVKWQFDVWSNDVTLANHM 857
            |.||.....|.|.|::....|...|...:.||:|||:|.|..||:|:...::.::.|:|||||..
Zfish   547 PTHAVQIALMALKMMELSDEVTTPMGEVIRMRIGIHSGSVLAGVVGVKMPRYCLFGNNVTLANKF 611

  Fly   858 ESGGIPGRVHITKETLKCL 876
            ||..:|.:::::..|.:.|
Zfish   612 ESCSLPRKINVSPTTYRLL 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43373	NP_001097622.2	AC_N	<523..720	CDD:292831	46/236 (19%)
		CYCc	686..881	CDD:214485	62/196 (32%)
		Guanylate_cyc	722..895	CDD:278633	54/160 (34%)
		DUF1053	<949..1005	CDD:283888
		CYCc	1259..1455	CDD:214485
		Guanylate_cyc	1285..1479	CDD:278633
gucy1a1	NP_001296458.1	HNOBA	279..470	CDD:285003	48/232 (21%)
		CYCc	449..635	CDD:214485	62/197 (31%)
		Guanylate_cyc	476..647	CDD:278633	54/160 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810