DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43373 and Gyc89Da

DIOPT Version :9

Sequence 1:	NP_001097622.2	Gene:	CG43373 / 39835	FlyBaseID:	FBgn0263131	Length:	1854	Species:	Drosophila melanogaster
Sequence 2:	NP_001036718.1	Gene:	Gyc89Da / 42001	FlyBaseID:	FBgn0038435	Length:	667	Species:	Drosophila melanogaster

Alignment Length:	282	Identity:	81/282 - (28%)
Similarity:	136/282 - (48%)	Gaps:	40/282 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly  1203 NEEALLRYIIDSIFLFAFMLALIF-----HSHQTEATYRLDFIWKLQATEEKEDMEHLQAYNRKL 1262
            |...|.|.::.:.:.....|.::|     .|.:.|.:..|...||.|..|              |
  Fly   413 NPHGLSRELVMAGWQHCSKLEIMFEKEEQRSDELEKSLELADSWKRQGDE--------------L 463

  Fly  1263 LENILPVHVAEHFLSREKHLDDLYHEQCDSVCILFASIPN-FSEFYVELEGNNEGVECLRLLNEI 1326
            |.:::|..:||.....|:.:...:.|    |.::|..:.| :.|....::|   .::.:..||::
  Fly   464 LYSMIPRPIAERMRLSEEQVCQSFEE----VSVIFLEVMNVYDEGLNSIQG---AMQTVNTLNKV 521

  Fly  1327 IADFD-ELLSEERFRCIEKIKSTGATYMAASGLTANTCDRVNFSHVTAMADYALQLFDKIEEVNM 1390
            .:..| |::|.    .:.|:::.|..|||.||     ...||..|.....|.||::..|.:   .
  Fly   522 FSALDEEIISP----FVYKVETVGMVYMAVSG-----APDVNPLHAEHACDLALRVMKKFK---A 574

  Fly  1391 HSFNNFRMRIGINIGPVVAGVIGACKPQYDIWGNAVNVASRMDSTGLVDHIQVTQEMQQILEGRG 1455
            |...:..:|:|||.|||||||:|...|:|.::|:.||.||||:|:.....||:::.....:...|
  Fly   575 HDMGDVAIRVGINSGPVVAGVVGQKVPRYCLFGDTVNTASRMESSSDPWKIQLSKYTGDKVRQVG 639

  Fly  1456 FELTCRGSVDVKGKGSMITYFL 1477
            :::..||:|.|||||.|.||:|
  Fly   640 YKVESRGTVQVKGKGDMETYWL 661

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43373	NP_001097622.2	AC_N	<523..720	CDD:292831
		CYCc	686..881	CDD:214485
		Guanylate_cyc	722..895	CDD:278633
		DUF1053	<949..1005	CDD:283888
		CYCc	1259..1455	CDD:214485	56/197 (28%)
		Guanylate_cyc	1285..1479	CDD:278633	63/195 (32%)
Gyc89Da	NP_001036718.1	HNOB	2..161	CDD:285002
		HNOBA	218..476	CDD:285003	17/76 (22%)
		CYCc	457..643	CDD:214485	60/218 (28%)
		Guanylate_cyc	485..662	CDD:278633	63/196 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453949
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740